Stem cells and 3D printing join forces to mend broken bones and arthritic knees
NCT ID NCT07628010
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a combination of a patient's own stem cells and platelet-rich plasma to help heal broken bones that won't mend on their own and to treat knee arthritis. For people needing a knee replacement, doctors use custom 3D-printed guides made from the patient's scans to improve surgical precision. The goal is to see if these approaches are safe and can speed healing, reduce pain, and improve mobility.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Autologous mesenchymal stromal cells combined with platelet-rich plasma (MSC-PRP)
- What this could lead to
- If it works, this could offer a way to heal stubborn bone fractures and ease knee arthritis without major surgery, and make knee replacements more precise with faster recovery.
- What could go wrong
- This is an early-stage study with only 100 participants, so results may not apply to everyone. There is also a small risk of infection or reaction at the injection or surgical site.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Zaporizhzhia State Medical and Pharamaceutical University
Zaporizhzhya, Ukraine
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