Freezing nerves before knee replacement may cut opioid use
NCT ID NCT05840276
First seen Jan 07, 2026 · Last updated May 13, 2026 · Updated 15 times
Summary
This study tests a treatment called cryoneurolysis, which uses cold to temporarily freeze nerves around the knee before replacement surgery. The goal is to see if it reduces pain and the need for strong painkillers (opioids) after surgery. About 100 adults scheduled for knee replacement will either get the real freezing treatment or a fake (sham) one. Researchers will compare opioid use and pain levels for up to 6 months after surgery.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Hospital of Southwest Jutland
Esbjerg, Region Syddanmark, 6700, Denmark
Conditions
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