Could donor stem cells ease knee pain? new trial aims to find out

NCT ID NCT05526001

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 3 trial tests whether a single injection of ELIXCYTE, made from donor stem cells, can reduce knee pain better than a placebo (saline). About 165 adults aged 40-80 with moderate knee osteoarthritis who haven't gotten relief from standard treatments are participating. The study is double-blind, meaning neither patients nor doctors know who gets the real treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ELIXCYTE (adipose-derived stem cells from donors)

What this could lead to

If it works, this could provide a new, non-surgical option to reduce knee pain and improve function in people with osteoarthritis.

What could go wrong

This is a Phase 3 trial, but it's still experimental. The stem cells may not work better than a placebo, and there could be side effects like joint pain or infection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for KNEE OSTEOARTHRITIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chang Gung Memorial Hospital, Linkou

    Taoyuan, 333, Taiwan

  • National Taiwan University Hospital

    Taipei, Taiwan

  • Taipei Medical University Shuang-Ho Hospital

    New Taipei City, Taiwan, 23561, Taiwan

  • Taipei Veterans General Hospital

    Taipei, 112, Taiwan