Could donor stem cells ease knee pain? new trial aims to find out
NCT ID NCT05526001
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 3 trial tests whether a single injection of ELIXCYTE, made from donor stem cells, can reduce knee pain better than a placebo (saline). About 165 adults aged 40-80 with moderate knee osteoarthritis who haven't gotten relief from standard treatments are participating. The study is double-blind, meaning neither patients nor doctors know who gets the real treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ELIXCYTE (adipose-derived stem cells from donors)
- What this could lead to
- If it works, this could provide a new, non-surgical option to reduce knee pain and improve function in people with osteoarthritis.
- What could go wrong
- This is a Phase 3 trial, but it's still experimental. The stem cells may not work better than a placebo, and there could be side effects like joint pain or infection.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Chang Gung Memorial Hospital, Linkou
Taoyuan, 333, Taiwan
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National Taiwan University Hospital
Taipei, Taiwan
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Taipei Medical University Shuang-Ho Hospital
New Taipei City, Taiwan, 23561, Taiwan
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Taipei Veterans General Hospital
Taipei, 112, Taiwan
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Other studies related to the condition(s) this trial covers.
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- Blocking knee blood vessels may offer new pain relief for severe osteoarthritis
- Which knee implant lasts longer? a Head-to-Head test
- Can cutting carbs curb knee pain? a diet trial puts it to the test
- Can virtual reality make knee pain therapy more engaging?
- Can a stem cell shot rebuild Worn-Out knees?