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One-Shot knee injection could ease arthritis pain

NCT ID NCT07225829

Ongoing Symptom relief Sponsor: 4Moving Biotech Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 28, 2026 · Updated 2 times

Summary

This study tests a single injection called 4P004 for people with knee osteoarthritis and synovitis (inflammation). About 129 adults aged 40-80 will receive either the injection or a placebo. The goal is to see if it reduces daily knee pain and improves function over 12 weeks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee synovitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KNEE OSTEOARTHRITIS SYNOVITIS OF KNEE

Contacts and locations

Locations

  • CHU Montpellier

    Montpellier, France

  • Care Access Kraków

    Krakow, Poland

  • Centre Hospitalier Universitaire CHU de Reims - Hopital Maison Blanche

    Reims, France

  • Centrum Medyczne Reuma Park

    Warsaw, Poland

  • ChU de Nice

    Nice, France

  • Clinica Nuestra Senora de la Esperanza

    Santiago de Compostela, Spain

  • Clínica Gaias Santiago

    A Coruña, 15702, Spain

  • Complejo Hospitalario Universitario de A Coruna - Hospital Universitario de A Coruna

    A Coruña, Spain

  • Corporacio Sanitaria Parc Tauli - Hospital de Sabadell

    Sabadell, Spain

  • Durham Bone and Joint Specialists

    Ajax, Canada

  • G.R.M.O. (Groupe de recherche en maladies osseuses) Inc

    Québec, Canada

  • HLA Clínica Vistahermosa

    Alicante, Spain

  • Hospital Quirónsalud Sagrado Corazón

    Seville, Spain

  • Hôpital Cochin

    Paris, France

  • Hôpital Lariboisière

    Paris, France

  • MICS Centrum Medyczne Warszawa

    Warsaw, Poland

  • Northwestern University Feinberg School of Medicine

    Chicago, Illinois, 60611, United States

  • Parker Institute Bispebjerg, Frederiksberg Hospital

    Frederiksberg, Denmark

  • SJHC London Rheumatology Centre

    London, Canada

  • Sanos Clinic Herlev

    Herlev, Denmark

  • Skylight Health Research Burlington

    Burlington, Massachusetts, 01803, United States

  • Tucson Orthopaedic Institute

    Tucson, Arizona, 85712-2805, United States

More trials for these conditions

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