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Multiple health conditions may slow knee replacement recovery

NCT ID NCT07882316

Knowledge-focused Sponsor: Balikesir Ataturk City Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Oct 20, 2026 · Last updated Oct 21, 2026 · Updated 1 time

Summary

Researchers are studying whether having more other health conditions before knee replacement surgery is linked to poorer physical function afterward. About 230 adults with knee osteoarthritis who are scheduled for a first knee replacement at one hospital in Türkiye will take part. The study measures health conditions before surgery and tracks function, pain, anxiety, and depression before surgery and at 6 and 12 months after. All patients receive routine care; the study adds no experimental treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If researchers find a link, doctors could better predict which patients need extra support after knee replacement and tailor rehabilitation plans.
What could go wrong
This is an observational study at a single hospital, so it can show associations but not prove cause and effect. Findings may not apply to other hospitals or patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 230 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Aug 2028

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of adult patients aged 18 years or older with primary knee osteoarthritis who are scheduled to undergo elective unilateral primary total knee arthroplasty at the Department of Orthopedics and Traumatology, Balikesir Ataturk City Hospital, Türkiye. Eligible patients will be consecutively recruited during the study enrollment period. All participants will receive standard surgical treatment and postoperative rehabilitation according to routine institutional practice. Participants will be followed prospectively, with clinical and patient-reported outcome assessments performed preoperatively and at 6 and 12 months after surgery.

Ages

18 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older. * Scheduled for elective unilateral primary total knee arthroplasty due to primary knee osteoarthritis. * Sufficient cognitive and communication abilities to understand and complete the study questionnaires. * Provision of written informed consent for study participation. Exclusion Criteria: * Patients scheduled for revision total knee arthroplasty. * Patients scheduled for simultaneous bilateral total knee arthroplasty. * Arthroplasty indicated for inflammatory arthritis, tumor, infection, or post-traumatic conditions. * Severe cognitive impairment, advanced dementia, or communication difficulties preventing valid completion of the study questionnaires. * Significant logistical or legal circumstances preventing completion of the planned follow-up assessments.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee osteoarthritis Multimorbidity

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Güneş Sarikaya

    RECRUITING

    Balıkesir, +90(543)673-3113, Turkey (Türkiye)

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