Effects of Low-Load blood flow restriction resistance with and without hip abductor strength training on pain, range of motion, strength and function in patients with knee osteoarthritis.
NCT ID NCT07892144
First seen Oct 23, 2026 · Last updated Oct 23, 2026
Summary
This study aims to compare the effects of low-load Blood Flow Restriction (BFR) resistance training with and without hip abductor strengthening in patients with knee osteoarthritis. It will evaluate the effectiveness of both treatment approaches in reducing knee pain, improving range of motion, increasing muscle strength, and enhancing functional ability. The study will determine which intervention provides better clinical outcomes in patients with knee osteoarthritis.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 44 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Both genders. Age 40-60 years. BMI (kg/m 2 ) \< 30 Have unilateral or bilateral knee OA. Have radiographic OA severity of Kellgren-Lawrence Grade I-II. Knee pain ≥3 months. Report pain intensity of ≥4-6/1 0 on Numeric Pain rating scale. Be able to walk independently without assistive devices Exclusion Criteria: * Total Knee replacement Deep venous thrombosis. Severe Cardiovascular disorders.(such as Acute myocardial infarction, peripheral arterial disease) Uncontrolled hypertension and diabetes. Acute knee injury within the last 6 months. Significant ligament tears (ACL, PCL, MCL, LCL). Knee surgery within the last 6-1 2 months. Lower limb Fractures
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Management & Technology
Lahore, Punjab Province, 54000, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Efficacy and safety study of the fixed-dose combination of Celecoxib/Acetaminophen compared to celecoxib for the treatment of pain in patients diagnosed with osteoarthritis in acute exacerbation
- Effects of visual and vestibular rehabilitation on postural stability, pain, functional status, and lower extremity biomechanics in individuals with knee osteoarthritis: a randomized controlled trial
- Low-Dose radiotherapy for painful knee osteoarthritis: a multicenter, interdisciplinary, prospective Single-Arm study
- Multiple health conditions may slow knee replacement recovery
- Can Bone-Protecting drugs shield knee cartilage from Walk-Induced breakdown?
- Knee braces put to the test in large Real-World registry