Effects of Low-Load blood flow restriction resistance with and without hip abductor strength training on pain, range of motion, strength and function in patients with knee osteoarthritis.

NCT ID NCT07892144

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

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Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
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Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
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The treatment has been approved, so it is available normally rather than through this programme.

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First seen Oct 23, 2026 · Last updated Oct 23, 2026

Summary

This study aims to compare the effects of low-load Blood Flow Restriction (BFR) resistance training with and without hip abductor strengthening in patients with knee osteoarthritis. It will evaluate the effectiveness of both treatment approaches in reducing knee pain, improving range of motion, increasing muscle strength, and enhancing functional ability. The study will determine which intervention provides better clinical outcomes in patients with knee osteoarthritis.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 44 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Both genders. Age 40-60 years. BMI (kg/m 2 ) \< 30 Have unilateral or bilateral knee OA. Have radiographic OA severity of Kellgren-Lawrence Grade I-II. Knee pain ≥3 months. Report pain intensity of ≥4-6/1 0 on Numeric Pain rating scale. Be able to walk independently without assistive devices Exclusion Criteria: * Total Knee replacement Deep venous thrombosis. Severe Cardiovascular disorders.(such as Acute myocardial infarction, peripheral arterial disease) Uncontrolled hypertension and diabetes. Acute knee injury within the last 6 months. Significant ligament tears (ACL, PCL, MCL, LCL). Knee surgery within the last 6-1 2 months. Lower limb Fractures

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

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  3. A doctor treating you

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Contacts and locations

Locations

  • University of Management & Technology

    Lahore, Punjab Province, 54000, Pakistan

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