Ancient ejiao paste put to the test for aching knees

NCT ID NCT07504562

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This Phase 2 trial tests whether a paste made with ejiao (a traditional Chinese ingredient) can reduce knee pain in people with osteoarthritis. Sixty adults with knee pain will use either the ejiao paste, a similar paste without ejiao, or a synthetic control. The study aims to see if the ejiao paste provides extra pain relief over 12 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Knee Pain Ejiao Paste (contains Colla Corii Asini, also known as ejiao)

What this could lead to

If it works, this could provide a new option for easing knee pain in people with osteoarthritis.

What could go wrong

This is a small, early-phase trial with only 60 participants. The treatment may not prove more effective than the placebo-like control paste.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Shanghai Municipal Hospital of Traditional Chinese Medicine

    Shanghai, Shanghai Municipality, 201801, China

  • Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine

    Shanghai, Shanghai Municipality, 201203, China