Could donor cells ease knee pain without surgery?
NCT ID NCT06208241
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase trial tests the safety of Allocetra-OTS, a cell therapy made from donor immune cells, injected into the knee joint of 18 people with end-stage osteoarthritis who are candidates for surgery. Researchers will monitor side effects and measure pain relief using a standard pain scale. The study is not yet recruiting and focuses on safety first.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Allocetra-OTS (a cell therapy made from donor immune cells)
- What this could lead to
- If safe and effective, this could point toward a new non-surgical option for severe knee osteoarthritis pain.
- What could go wrong
- This is a very early, small pilot study with only 18 people, so results may not apply widely. The main goal is safety, not proof of effectiveness.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
Kaplan Medical Center
Rehovot, Israel
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