Infectious disease
MONDO:0005550A disorder directly resulting from the presence and activity of a microbial, viral, or parasitic agent in humans. It can be transmitted by direct or indirect contact.
Also known as: communicable disease, infection, infectious, infectious disease, infectious diseases and manifestations, infectious disorder, transmissible disease, clinical infection
8226 clinical trials for this condition and its sub-types, 298 tagged with Infectious disease itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Infectious disease
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Viral infectious disease 134 trials · 4,446 incl. sub-types
42 sub-types
- Primary viral infectious disease 0 trials · 4,251 incl. sub-types Sub-types →
- Viral respiratory tract infection 47 trials · 566 incl. sub-types Sub-types →
- Coronavinae infectious disease 136 trials
- Disease arising from reactivation of latent virus 4 trials · 89 incl. sub-types Sub-types →
- Viral infection of central nervous system 3 trials · 58 incl. sub-types Sub-types →
- Viral hemorrhagic fever 10 trials · 51 incl. sub-types Sub-types →
- Arbovirus fever 0 trials · 46 incl. sub-types Sub-types →
- Kaposi's sarcoma 45 trials Sub-types →
- Human T-lymphotropic virus 1 infectious disease 5 trials · 34 incl. sub-types Sub-types →
- Rabies 27 trials
- Common wart 26 trials
- Vaccinia 17 trials
- Virus-associated trichodysplasia spinulosa 10 trials
- Immunodeficiency 32B 9 trials
- Arbovirus infection 8 trials
- Viral eye infection 0 trials · 8 incl. sub-types Sub-types →
- COVID-19–associated multisystem inflammatory syndrome in children 7 trials
- Human infection by orthopoxvirus 5 trials
- Herpangina 3 trials
- Milker's nodule 3 trials
- Human betaherpesvirus 5 infectious disease 2 trials
- Parvoviridae infectious disease 1 trial Sub-types →
- Zika virus congenital syndrome 1 trial
- Molluscum contagiosum 1 trial
- Pharyngoconjunctival fever 1 trial
- Newcastle disease 0 trials
- Reoviridae infectious disease 0 trials
- Whitewater Arroyo hemorrhagic fever 0 trials
- Congenital Epstein-Barr virus infection 0 trials
- Congenital varicella syndrome 0 trials
- Contagious pustular dermatitis 0 trials
- Epidemic pleurodynia 0 trials
- Exanthema subitum 0 trials
- Focal epithelial hyperplasia 0 trials
- Infective dermatitis associated with HTLV-1 0 trials
- Lumpy skin disease 0 trials
- Neurolymphomatosis 0 trials
- Pseudorabies 0 trials
- Viral esophagitis 0 trials
- Viral gastritis 0 trials Sub-types →
- Viral labyrinthitis 0 trials
- Viral myositis 0 trials
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Bacterial infectious disease 96 trials · 2,078 incl. sub-types
52 sub-types
- Primary bacterial infectious disease 0 trials · 592 incl. sub-types Sub-types →
- Mycobacterial infectious disease 23 trials · 361 incl. sub-types Sub-types →
- Gram-negative bacterial infections 33 trials · 301 incl. sub-types Sub-types →
- Commensal bacterial infectious disease 0 trials · 273 incl. sub-types Sub-types →
- Gram-positive bacterial infections 7 trials · 253 incl. sub-types Sub-types →
- Pulpitis 191 trials
- Bacterial sexually transmitted disease 8 trials · 114 incl. sub-types Sub-types →
- Bacterial infectious disease with sepsis 78 trials · 113 incl. sub-types Sub-types →
- Anaerobic bacteria infectious disease 2 trials · 100 incl. sub-types Sub-types →
- Spirochaetales infections 1 trial · 98 incl. sub-types Sub-types →
- Bacterial arthritis 24 trials · 94 incl. sub-types Sub-types →
- Staphylococcal infection 41 trials · 84 incl. sub-types Sub-types →
- Bacterial urinary tract infection 55 trials · 81 incl. sub-types Sub-types →
- Clostridium difficile colitis 69 trials
- Bacterial pneumonia 28 trials · 65 incl. sub-types Sub-types →
- Skin disease caused by bacterial infection 13 trials · 57 incl. sub-types Sub-types →
- Meningococcal infection 47 trials · 55 incl. sub-types Sub-types →
- Bifidobacteriales infectious disease 0 trials · 44 incl. sub-types Sub-types →
- Bacterial meningitis 12 trials · 37 incl. sub-types Sub-types →
- Pseudomonas infection 25 trials · 29 incl. sub-types Sub-types →
- Escherichia coli infection 26 trials Sub-types →
- Vibrio infectious disease 0 trials · 16 incl. sub-types Sub-types →
- Mycoplasmoides infection 7 trials · 15 incl. sub-types Sub-types →
- Bacterial endocarditis 15 trials
- Haemophilus infectious disease 14 trials Sub-types →
- Necrotizing soft tissue infection 13 trials Sub-types →
- Empyema 10 trials · 11 incl. sub-types Sub-types →
- Chorioamnionitis 10 trials
- Klebsiella infectious disease 5 trials · 9 incl. sub-types Sub-types →
- Rickettsiosis 2 trials · 7 incl. sub-types Sub-types →
- Tracheitis 2 trials · 7 incl. sub-types Sub-types →
- Enterococcus infectious disease 1 trial · 4 incl. sub-types Sub-types →
- Yersinia infectious disease 0 trials · 4 incl. sub-types Sub-types →
- Peritonsillar abscess 4 trials
- Bacterial conjunctivitis 3 trials Sub-types →
- Bacterial hemorrhagic fever 0 trials · 3 incl. sub-types Sub-types →
- Bacterial gastritis 2 trials
- Fournier gangrene 2 trials
- Septic peritonitis 2 trials
- Opportunistic bacterial infectious disease 0 trials · 1 incl. sub-types Sub-types →
- Actinobacillus infectious disease 0 trials
- Aeromonas hydrophila infectious disease 0 trials Sub-types →
- Pectobacterium carotovorum infection 0 trials
- Proteus infectious disease 0 trials
- Whipple disease 0 trials
- Bacterial myositis 0 trials Sub-types →
- Botryomycosis 0 trials Sub-types →
- Idiopathic severe pneumococcemia 0 trials
- Noma 0 trials
- Pasteurellosis 0 trials Sub-types →
- Pneumonic pasteurellosis 0 trials
- Rat-bite fever 0 trials Sub-types →
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Sexually transmitted disease 127 trials · 1,708 incl. sub-types
3 sub-types
- Viral sexually transmitted disease 5 trials · 1,593 incl. sub-types Sub-types →
- Bacterial sexually transmitted disease 8 trials · 114 incl. sub-types Sub-types →
- Trichomonas vaginitis urogenital infection 7 trials Sub-types →
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Respiratory tract infectious disorder 176 trials · 1,333 incl. sub-types
14 sub-types
- Pneumonia 326 trials · 610 incl. sub-types Sub-types →
- Viral respiratory tract infection 47 trials · 566 incl. sub-types Sub-types →
- Fungal lung infectious disease 6 trials · 57 incl. sub-types Sub-types →
- Pulmonary non-tuberculous mycobacterial infection 48 trials
- Streptococcal sore throat 8 trials
- Pleural tuberculosis 7 trials Sub-types →
- Tracheitis 2 trials · 7 incl. sub-types Sub-types →
- Lung abscess 3 trials
- Pneumonic plague 3 trials
- Tuberculous fibrosis of lung 3 trials
- Laryngeal diphtheria 0 trials
- Laryngeal tuberculosis 0 trials
- Nasopharyngeal diphtheria 0 trials
- Silicotuberculosis 0 trials
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Digestive system infectious disorder 4 trials · 605 incl. sub-types
22 sub-types
- Viral hepatitis 12 trials · 443 incl. sub-types Sub-types →
- Infectious colitis 0 trials · 69 incl. sub-types Sub-types →
- Intestinal infectious disease 3 trials · 49 incl. sub-types Sub-types →
- Small intestinal bacterial overgrowth 18 trials
- Parasitic intestinal disorder 0 trials · 16 incl. sub-types Sub-types →
- Liver abscess (disease) 4 trials
- Campylobacteriosis 3 trials Sub-types →
- Bacterial gastritis 2 trials
- Gastrointestinal tuberculosis 0 trials · 2 incl. sub-types Sub-types →
- Aeromonas hydrophila intestinal disease 0 trials
- Salmonella gastroenteritis 0 trials
- Whipple disease 0 trials
- Anal verrucous carcinoma 0 trials
- Bacterial esophagitis 0 trials
- Colorectal Kaposi sarcoma 0 trials Sub-types →
- Fungal esophagitis 0 trials Sub-types →
- Fungal gastritis 0 trials
- Internal hirudiniasis 0 trials
- Oropharyngeal anthrax 0 trials
- Polycystic echinococcosis 0 trials
- Viral esophagitis 0 trials
- Viral gastritis 0 trials Sub-types →
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Infectious disease with sepsis 382 trials · 474 incl. sub-types
1 sub-type
- Bacterial infectious disease with sepsis 78 trials · 113 incl. sub-types Sub-types →
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Vector-borne disease 9 trials · 450 incl. sub-types
49 sub-types
- Malaria 135 trials · 170 incl. sub-types Sub-types →
- Dengue disease 75 trials Sub-types →
- Tick-borne infectious disease 9 trials · 41 incl. sub-types Sub-types →
- Chikungunya 31 trials
- Leishmaniasis 8 trials · 27 incl. sub-types Sub-types →
- Mycobacterium avium complex disease 22 trials
- Schistosomiasis 15 trials · 17 incl. sub-types Sub-types →
- Yellow fever 16 trials
- Zika virus infectious disease 15 trials
- Chagas disease 12 trials
- Filarial elephantiasis 9 trials
- Onchocerciasis 9 trials Sub-types →
- Arbovirus infection 8 trials
- Lassa fever 6 trials
- Crimean-Congo hemorrhagic fever 5 trials
- Mosquito-borne viral encephalitis 0 trials · 5 incl. sub-types Sub-types →
- Listeriosis 4 trials Sub-types →
- Plague 2 trials · 4 incl. sub-types Sub-types →
- Q fever 3 trials
- Rift valley fever 3 trials
- Human African trypanosomiasis 2 trials · 3 incl. sub-types Sub-types →
- Typhus 0 trials · 3 incl. sub-types Sub-types →
- Hantavirus hemorrhagic fever with renal syndrome, Puumala virus type 2 trials
- Hantavirus pulmonary syndrome 2 trials
- Relapsing fever 2 trials Sub-types →
- Oropouche fever 1 trial
- Venezuelan equine encephalitis 1 trial
- West Nile fever 1 trial Sub-types →
- Zika virus congenital syndrome 1 trial
- Lymphocytic choriomeningitis 1 trial
- Spotted fever 0 trials · 1 incl. sub-types Sub-types →
- Tungiasis 1 trial
- Alkhurma hemorrhagic fever 0 trials
- Argentine hemorrhagic fever 0 trials
- Bolivian hemorrhagic fever 0 trials
- Colorado tick fever 0 trials
- Hantavirus hemorrhagic fever with renal syndrome, Dobrava-Belgrade virus type 0 trials
- Hantavirus hemorrhagic fever with renal syndrome, Seoul virus type 0 trials
- Murray valley encephalitis 0 trials
- O'nyong'nyong fever 0 trials
- Ross river fever 0 trials
- Venezuelan hemorrhagic fever 0 trials
- Whitewater Arroyo hemorrhagic fever 0 trials
- Bacterial esophagitis 0 trials
- Fungal esophagitis 0 trials Sub-types →
- Phlebotomus fever 0 trials
- Rat-bite fever 0 trials Sub-types →
- Trench fever 0 trials
- Tularemia 0 trials Sub-types →
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Skin disorder caused by infection 3 trials · 349 incl. sub-types
15 sub-types
- Skin infection 12 trials · 152 incl. sub-types Sub-types →
- Herpes zoster 73 trials Sub-types →
- Skin disease caused by bacterial infection 13 trials · 57 incl. sub-types Sub-types →
- Parasitic skin disorder 1 trial · 37 incl. sub-types Sub-types →
- Chickenpox 26 trials
- Common wart 26 trials
- Virus-associated trichodysplasia spinulosa 10 trials
- Plantar wart 9 trials
- Hand, foot and mouth disease 7 trials
- Viral exanthem 0 trials · 3 incl. sub-types Sub-types →
- Epstein-Barr virus hepatitis 0 trials
- Exanthema subitum 0 trials
- Herpetic whitlow 0 trials
- Infective dermatitis associated with HTLV-1 0 trials
- Variola major infectious disease 0 trials
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Parasitic infectious disease 12 trials · 343 incl. sub-types
17 sub-types
- Protozoa infectious disease 3 trials · 242 incl. sub-types Sub-types →
- Helminthiasis 13 trials · 67 incl. sub-types Sub-types →
- Parasitic skin disorder 1 trial · 37 incl. sub-types Sub-types →
- Parasitic eye infection 0 trials · 16 incl. sub-types Sub-types →
- Parasitic intestinal disorder 0 trials · 16 incl. sub-types Sub-types →
- Cryptococcosis 5 trials · 10 incl. sub-types Sub-types →
- Demodicidosis 5 trials · 6 incl. sub-types Sub-types →
- Parasitemia 5 trials
- Coccidioidomycosis 4 trials
- Amoebiasis due to Entamoeba histolytica 1 trial
- Amoebiasis due to free-living amoebae 1 trial
- Strongylida infectious disease 0 trials
- Cutaneous larva migrans 0 trials Sub-types →
- Distomatosis 0 trials
- Microsporidiosis 0 trials Sub-types →
- Parasitic Ichthyosporea infectious disease 0 trials Sub-types →
- Parasitic myositis 0 trials Sub-types →
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Fungal infectious disease 38 trials · 293 incl. sub-types
18 sub-types
- Opportunistic mycosis 0 trials · 147 incl. sub-types Sub-types →
- Cutaneous mycosis 1 trial · 118 incl. sub-types Sub-types →
- Fungal lung infectious disease 6 trials · 57 incl. sub-types Sub-types →
- Systemic mycosis 27 trials · 54 incl. sub-types Sub-types →
- Pneumocystis infectious disease 4 trials · 19 incl. sub-types Sub-types →
- Fungal meningitis 3 trials · 10 incl. sub-types Sub-types →
- Fungal infection of eye 0 trials · 7 incl. sub-types Sub-types →
- Scedosporiosis 2 trials
- Sporotrichosis 1 trial Sub-types →
- Alternariosis 0 trials Sub-types →
- Emergomycosis 0 trials
- Fungal discitis 0 trials
- Fungal esophagitis 0 trials Sub-types →
- Fungal gastritis 0 trials
- Fungal myositis 0 trials
- Invasive scopulariopsis infection 0 trials
- Mycotic endocarditis 0 trials
- Mycotoxicosis 0 trials Sub-types →
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Urinary tract infection 156 trials · 250 incl. sub-types
5 sub-types
- Bacterial urinary tract infection 55 trials · 81 incl. sub-types Sub-types →
- Renal infectious disease 16 trials · 64 incl. sub-types Sub-types →
- Trichomonas vaginitis urogenital infection 7 trials Sub-types →
- Urinary schistosomiasis 3 trials
- Pyoureter 0 trials
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Infectious disorder of the nervous system 4 trials · 232 incl. sub-types
10 sub-types
- Central nervous system infectious disorder 10 trials · 163 incl. sub-types Sub-types →
- Tetanus 44 trials Sub-types →
- Rabies 27 trials
- Tropical spastic paraparesis 3 trials
- Cytomegalovirus retinitis 2 trials
- Tabes dorsalis 2 trials
- Histoplasmosis retinitis 1 trial
- Ophthalmic herpes zoster 0 trials
- Postinfectious cerebellitis 0 trials
- Tick paralysis 0 trials
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Nosocomial infection 115 trials · 116 incl. sub-types
3 sub-types
- Iatrogenic Kaposi's sarcoma 1 trial
- Iatrogenic Creutzfeldt-Jakob disease 0 trials
- Iatrogenic botulism 0 trials
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Infective arthritis 25 trials · 100 incl. sub-types
2 sub-types
- Bacterial arthritis 24 trials · 94 incl. sub-types Sub-types →
- Infectious discitis 4 trials Sub-types →
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Eye infectious disorder 4 trials · 61 incl. sub-types
10 sub-types
- Endophthalmitis 9 trials · 38 incl. sub-types Sub-types →
- Parasitic eye infection 0 trials · 16 incl. sub-types Sub-types →
- Viral eye infection 0 trials · 8 incl. sub-types Sub-types →
- Fungal infection of eye 0 trials · 7 incl. sub-types Sub-types →
- Hordeolum 1 trial · 7 incl. sub-types Sub-types →
- Bacterial conjunctivitis 3 trials Sub-types →
- Infectious panuveitis 1 trial
- Chronic canaliculitis 0 trials
- Infectious scleritis 0 trials
- Ocular tuberculosis 0 trials
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Infective vaginitis 1 trial · 61 incl. sub-types
4 sub-types
- Bacterial vaginosis 44 trials
- Vulvovaginal candidiasis 25 trials
- Trichomonal vulvovaginitis 1 trial
- Herpetic vulvovaginitis 0 trials
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Hemorrhagic fever 4 trials · 54 incl. sub-types
2 sub-types
- Viral hemorrhagic fever 10 trials · 51 incl. sub-types Sub-types →
- Bacterial hemorrhagic fever 0 trials · 3 incl. sub-types Sub-types →
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Infective endocarditis 46 trials · 52 incl. sub-types
3 sub-types
- Bacterial endocarditis 15 trials
- Subacute bacterial endocarditis 4 trials
- Mycotic endocarditis 0 trials
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Prosthesis-related infectious disease 49 trials
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Ear infection 9 trials · 40 incl. sub-types
5 sub-types
- Infectious otitis media 24 trials
- Otitis externa 3 trials · 12 incl. sub-types Sub-types →
- Geniculate herpes zoster 0 trials
- Infectious otitis interna 0 trials
- Viral labyrinthitis 0 trials
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Abscess 10 trials · 34 incl. sub-types
11 sub-types
- Breast abscess 5 trials
- Epidural abscess 5 trials
- Liver abscess (disease) 4 trials
- Peritonsillar abscess 4 trials
- Intracranial abscess 3 trials
- Lung abscess 3 trials
- Corneal abscess 1 trial
- Intersphincteric abscess 0 trials
- Pyoureter 0 trials
- Splenic abscess 0 trials
- Vitreous abscess 0 trials
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Infectious embryofetopathy 2 trials · 25 incl. sub-types
10 sub-types
- Congenital herpes virus infection 0 trials · 15 incl. sub-types Sub-types →
- Congenital syphilis 7 trials Sub-types →
- Congenital toxoplasmosis 2 trials
- Congenital Epstein-Barr virus infection 0 trials
- Congenital enterovirus infection 0 trials
- Congenital rubella syndrome 0 trials
- Congenital varicella syndrome 0 trials
- Fetal enterovirus syndrome 0 trials
- Fetal parainfluenza virus type 3 syndrome 0 trials
- Fetal parvovirus syndrome 0 trials
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Infectious peritonitis 22 trials · 23 incl. sub-types
3 sub-types
- Septic peritonitis 2 trials
- Diphtheritic peritonitis 0 trials
- Tuberculous peritonitis 0 trials
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Nail infection 0 trials · 14 incl. sub-types
3 sub-types
- Tinea unguium 14 trials
- Fungal infection of the toenail 4 trials
- Herpetic whitlow 0 trials
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Coinfection 12 trials
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Hookworm infectious disease 10 trials
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Puerperal infection 9 trials
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Acanthamoeba infectious disease 0 trials · 5 incl. sub-types
2 sub-types
- Acanthamoeba keratitis 5 trials
- Granulomatous amebic encephalitis 0 trials
-
Epididymitis 2 trials
2 sub-types
- Epididymo-orchitis 0 trials Sub-types →
- Tuberculous epididymitis 0 trials
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Mycetoma 1 trial
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Ciliophora infectious disease 0 trials
1 sub-type
- Balantidiasis 0 trials
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Hirudiniasis 0 trials
2 sub-types
- External hirudiniasis 0 trials
- Internal hirudiniasis 0 trials
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Infectious myositis 0 trials
1 sub-type
- Parasitic myositis 0 trials Sub-types →
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Protothecosis 0 trials
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Pythiosis 0 trials
Most studied deeper sub-types
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Booster shot for Moms-to-Be could shield newborns from deadly infections
Vaccine OngoingThis study follows women who previously received the GBS-NN/NN2 vaccine during pregnancy to see how long their immune protection lasts. It also tests whether a booster dose given in a new pregnancy is safe and boosts immunity, aiming to protect newborns from group B strep infecti…
Phase 2/3 • Sponsor: Minervax ApS • Aim: Vaccine
Last updated Sep 06, 2026 00:00 UTC
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New shingles vaccine shows promise in Head-to-Head trial
Vaccine OngoingThis study tests a new shingles vaccine called JCXH-105 in healthy adults aged 50 and older. It compares the new vaccine to the current standard, Shingrix, to see if it is safe and triggers a strong immune response. About 467 participants will receive either JCXH-105 or Shingrix,…
Phase 2 • Sponsor: Immorna Biotherapeutics, Inc. • Aim: Vaccine
Last updated Jun 27, 2026 12:23 UTC
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New mRNA vaccine aims to shield older adults from RSV
Vaccine OngoingThis early-stage study tests an experimental mRNA vaccine called JCXH-108 to see if it is safe and triggers an immune response against RSV, a common respiratory virus. About 75 healthy volunteers, split into two age groups (18-45 and 60+), will receive either the vaccine or a pla…
Phase 1 • Sponsor: Immorna Biotherapeutics, Inc. • Aim: Vaccine
Last updated Jun 27, 2026 12:23 UTC
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Could a double-dose flu vaccine protect vulnerable transplant patients better?
Vaccine OngoingThis study compares high-dose and standard-dose flu vaccines in 396 adults who received a kidney, heart, or liver transplant within the past year. The goal is to see if a higher dose or two doses provide better protection against the flu. Results will help improve vaccine recomme…
Phase 2 • Sponsor: Vanderbilt University Medical Center • Aim: Vaccine
Last updated Jun 27, 2026 08:13 UTC
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MRNA HIV vaccine trial launches in healthy volunteers
Vaccine OngoingThis early-stage trial tests whether three experimental mRNA vaccines can safely teach the immune system to recognize and fight HIV. About 108 healthy, HIV-negative adults aged 18-55 will receive one of the vaccines. The main goal is to check for side effects and see if the vacci…
Phase 1 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Vaccine
Last updated Jun 27, 2026 07:54 UTC
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Protein-Packed breast milk could help tiny preemies grow stronger
Disease control OngoingThis study tests whether adding extra protein to breast milk during the first two weeks of life helps extremely preterm infants (born at 28 weeks or earlier) gain more lean body mass and develop a healthier gut microbiome. About 150 babies will be randomly assigned to receive eit…
Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Sep 21, 2026 13:01 UTC
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Drug could slash surgeries for rare airway disease
Disease control OngoingThis phase II trial tests whether bevacizumab, a drug that blocks blood vessel growth, can lengthen the time between surgeries for adults with recurrent respiratory papillomatosis (RRP), a rare condition causing wart-like growths in the airways. Participants receive 11 doses of t…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Sep 18, 2026 00:00 UTC
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Lung transplant patients may get better flu protection with high-dose vaccine
Disease control OngoingThis study compares a high-dose flu vaccine to the standard dose in 270 lung transplant recipients who are 1 to 35 months post-transplant. The goal is to see if the high-dose vaccine triggers a stronger immune response and provides better protection against influenza. Participant…
Phase 2 • Sponsor: Vanderbilt University Medical Center • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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Could a Parent's nose bacteria protect newborns from infection?
Disease control OngoingThis study tests whether giving a newborn a nasal microbiome transplant from their parent can increase the diversity of bacteria in the baby's nose. The goal is to see if this can help prevent infections like those caused by Staphylococcus aureus. The study involves 175 premature…
Phase 1 • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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Could a poop pill save lives? new trial targets superbug lung infections in ICU patients
Disease control CancelledThis study tests whether fecal microbiota transplantation (FMT) — transferring healthy donor stool into the gut — can lower the risk of death in ventilated ICU patients with multidrug-resistant lung infections. The idea is that restoring gut bacteria may help fight lung infection…
Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology • Aim: Disease control
Last updated Sep 04, 2026 00:00 UTC
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Can telemedicine bring IV antibiotics home?
Disease control OngoingThis trial tests a new model where patients with infections receive intravenous antibiotics at home instead of staying in the hospital. Nurses from a municipal response team visit the patient, while hospital doctors oversee the treatment remotely using telemedicine and welfare te…
Sponsor: Helse Møre og Romsdal HF • Aim: Disease control
Last updated Aug 26, 2026 00:00 UTC
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A new strategy aims to plug gaps in HIV care for people who inject drugs
Disease control OngoingThis trial tests whether a structured improvement strategy, called SAIA, can help syringe service programs in the U.S. deliver more HIV testing and referrals to prevention and treatment services. The study will compare programs using SAIA with those continuing their usual practic…
Sponsor: University of California, San Diego • Aim: Disease control
Last updated Aug 26, 2026 00:00 UTC
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Hospital at home: new study tests home care for infections
Disease control OngoingThis study looks at whether a special team of doctors and nurses can treat adults with suspected infections at home, instead of sending them to the hospital. About 500 people will be randomly assigned to either standard hospital care or home-based care from a mobile response team…
Sponsor: Copenhagen University Hospital at Herlev • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
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Could donor milk give late preterm babies a healthier start than formula?
Disease control PausedThis study compares banked donor breast milk to preterm formula for late preterm infants (born at 34–36 weeks) who need extra nutrition while their mothers' milk supply increases. Researchers will track the babies' weight gain and analyze their gut bacteria to see which supplemen…
Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Could one dose beat days of antibiotics for pancreatic surgery patients?
Disease control By invitation onlyThis study compares two antibiotic plans for adults having pancreatic surgery. One group gets a single dose of cefazolin before surgery, while the other gets a longer regimen. The goal is to see if the single dose works just as well to prevent infections. 558 participants will be…
Sponsor: Asan Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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Could simple mouth care prevent lung infections in preemies?
Disease control OngoingThis study looks at whether cleaning the mouth of very premature infants every 3-4 hours can reduce harmful bacteria and lower the risk of pneumonia and other breathing problems. Researchers will follow 40 infants born before 32 weeks and weighing less than 1500 grams, comparing …
Sponsor: University of Florida • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Can a sticky shield stop heart device infections?
Disease control OngoingThis study tests whether an iodine-coated barrier dressing applied before surgery can reduce bacteria around heart devices like pacemakers. About 390 adults having a device replacement or upgrade are randomly assigned to get the dressing before or after the incision. Researchers …
Sponsor: Ottawa Heart Institute Research Corporation • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
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Bringing the hospital to your living room: a massive study tests home care for common illnesses
Disease control By invitation onlyThis study looks at whether treating patients at home for conditions like infections, heart failure, diabetes, and COPD can lead to better health outcomes and satisfaction compared to traditional hospital stays. Nearly 10,000 adults will receive hospital-level care at home, inclu…
Sponsor: OSF Healthcare System • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Gut bacteria cocktail aimed at superbug infections – trial pulled before start
Disease control CancelledThis study planned to test a treatment called MET-2, a mix of gut bacteria, to help clear antibiotic-resistant germs from the body after a bloodstream infection. It was designed for adults not in intensive care who had a resistant infection. The trial was withdrawn before enrolli…
Phase 2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Can a common drug stop infections before they start?
Disease control OngoingThis pilot study tests whether the drug rapamycin (sirolimus) can help prevent infections or make them less severe. Fifteen adults will take the drug for 6 months while researchers monitor their health through blood tests, heart checks, and surveys. The goal is to see if rapamyci…
Sponsor: Hoskinson Health and Wellness Clinic • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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Baby formula with extra ingredients may cut infections and boost growth
Disease control OngoingThis study tests whether infant formula with added bioactive ingredients helps healthy babies grow well, tolerate the formula, and have fewer infections. About 456 full-term infants will receive either the test formula or a standard formula. Parents will report any infection symp…
Sponsor: FrieslandCampina • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Could a Parent's nose bacteria shield newborns from staph?
Disease control OngoingThis early study tests whether transferring a parent's healthy nasal bacteria to their newborn can help prevent staph infections. Researchers will give the baby a nasal spray containing the parent's bacteria or a placebo, then monitor the baby's nose bacteria and safety. The stud…
Phase 1 • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Can shorter antibiotic courses prevent infections in Kids' broken bones?
Disease control By invitation onlyThis study looks at 800 children with mild open fractures to see how much antibiotic is needed to prevent infections. Some kids get one dose, some get 24 hours, and some get 24 hours plus five days of pills. The goal is to find the best balance between preventing infection and av…
Phase 4 • Sponsor: St. Louis University • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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New antibiotic combo tested against superbugs in hospitals
Disease control By invitation onlyThis study tracks 100 hospital patients with hard-to-treat bacterial infections who receive the antibiotic combination aztreonam-avibactam. Researchers will measure how often the infection clears up without needing more antibiotics. The goal is to see how well this drug works in …
Sponsor: French Society for Intensive Care • Aim: Disease control
Last updated Jun 26, 2026 17:34 UTC
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Probiotics tested as infection shield for ICU patients
Disease control By invitation onlyThis study tests whether giving probiotics (Bacillus clausii) to critically ill adults can reduce serious infections like pneumonia and bloodstream infections. One hundred ICU patients will receive either the probiotic or a sugar pill, and researchers will track infection rates a…
Sponsor: Benha University • Aim: Disease control
Last updated Jun 26, 2026 16:10 UTC
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New finger clip could replace needles for sepsis monitoring
Diagnosis OngoingThis study tests a finger-clasp device called Lab Clasp that measures lactate from fluid just under the skin, similar to a pulse oximeter. Researchers want to see if it matches standard blood tests in 6 healthy adults. If it works, it could make sepsis monitoring easier and less …
Sponsor: Brigham and Women's Hospital • Aim: Diagnosis
Last updated Jul 18, 2026 00:00 UTC
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School staff trained to fight flu: will it work?
Prevention By invitation onlyThis study tests whether training school personnel in vaccine communication and providing promotional materials can increase flu vaccination rates among students. About 6,000 students from participating schools will be tracked. The goal is to see if these simple steps lead to mor…
Sponsor: University of Rochester • Aim: Prevention
Last updated Aug 27, 2026 00:00 UTC
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Hospital study aims to slash surgical infections by 88%
Prevention OngoingThis study tests different methods to stop the spread of dangerous bacteria in operating rooms and reduce infections after surgery. About 6,000 people having hip, knee, or spine surgery will take part. The goal is to find the best way to keep patients safe from infections.
Sponsor: Trustees of Dartmouth College • Aim: Prevention
Last updated Jul 10, 2026 00:00 UTC
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Could a sprinkle of antibiotic powder in joint surgery stop infections?
Prevention OngoingThis study looks at whether putting vancomycin powder directly into the joint during hip or knee replacement surgery can prevent infections better than standard IV antibiotics alone. About 1,800 adults having primary or revision joint replacement are being followed for two years.…
Sponsor: Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal • Aim: Prevention
Last updated Jun 26, 2026 16:38 UTC
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Do childhood infections shape a lifetime of immunity?
Knowledge-focused OngoingResearchers follow newborns in a German region to see how infections, the microbiome, and vaccinations interact as children's immune systems develop. The study tracks health data over time to understand why some children develop allergies or asthma. It aims to reveal patterns tha…
Sponsor: Helmholtz Centre for Infection Research • Aim: Knowledge-focused
Last updated Sep 21, 2026 13:00 UTC
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Bird flu rechallenge: scientists Re-Infect volunteers to unlock immune secrets
Knowledge-focused By invitation onlyThis study aims to understand how the immune system responds to a second infection with a mild bird flu virus (H10N7). Healthy adults who were infected with H10N7 in a previous study will be infected again and monitored closely in the hospital for 9 days. The goal is to learn mor…
Phase 1 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Sep 11, 2026 00:00 UTC
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AI toolkit aims to speed up epidemic response for diseases like COVID-19 and mpox
Knowledge-focused By invitation onlyThis study tests a new AI-powered toolkit designed to help public health officials at local CDC offices respond more quickly to emerging infectious diseases such as COVID-19, mpox, influenza, and dengue. The toolkit combines data analysis, risk assessment, decision support, and e…
Sponsor: Peking University • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC
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New drug zavicefta under Real-World watch for sepsis and kidney patients
Knowledge-focused OngoingThis study will observe how safe and effective the antibiotic Zavicefta is when used in everyday medical practice in Japan. It includes 59 patients with sepsis (a severe blood infection) or reduced kidney function who are receiving Zavicefta for the first time. Researchers will t…
Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Aug 19, 2026 00:00 UTC
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Can we finally outsmart recurrent yeast infections? a new study investigates
Knowledge-focused OngoingThis study aims to understand why some women get recurrent vaginal yeast infections (vulvovaginal candidiasis) and others don't. Researchers will compare the vaginal microbiome, immune markers, and metabolic profiles of women with and without the infection. By identifying key dif…
Sponsor: University Hospital, Antwerp • Aim: Knowledge-focused
Last updated Aug 15, 2026 00:00 UTC
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Leftover blood samples could unlock new medical discoveries
Knowledge-focused By invitation onlyThis study collects leftover blood or tissue samples and related health data from people who have already had lab tests at LabCorp. The goal is to build a large, de-identified resource that scientists can use for future research on pregnancy, cancer, and infectious diseases. Some…
Sponsor: Sequenom, Inc. • Aim: Knowledge-focused
Last updated Jul 23, 2026 00:00 UTC
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Genetic test could shorten hospital stays for fungal infection patients
Knowledge-focused CancelledThis study explores whether a genetic test (CYP2C19) can help doctors choose the right dose of the antifungal drug voriconazole more quickly. Patients starting voriconazole for an infection will give a blood sample for genotyping. The goal is to see if this personalized dosing re…
Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC
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Parenting program aims to boost health in latino kids
Knowledge-focused OngoingThis study tests if a special parenting program (Attachment Biobehavioral Catch-Up) can help low-income Latino children have fewer common illnesses, better sleep, and healthier weight. About 260 mothers and their 9-month-old babies will take part. The program focuses on strengthe…
Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Toronto study links Mom's gut bugs to Baby's future health
Knowledge-focused OngoingThis study looks at how the bacteria in a pregnant woman's gut (her microbiome) and her nutrition affect her baby's growth and health. Researchers are following 800 young pregnant women (28 and under) in Toronto throughout pregnancy and for a year after birth. They collect stool,…
Sponsor: The Hospital for Sick Children • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Gut bacteria may forecast surgery risks in pancreatic cancer patients
Knowledge-focused By invitation onlyThis study is collecting saliva, stool, blood, bile, and tumor samples from 200 people undergoing surgery for pancreatic or related cancers. Researchers want to see if the types of bacteria in these samples can help predict who will have complications after surgery and how the ca…
Sponsor: St. Antonius Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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AI sepsis predictor study pulled before it even started
Knowledge-focused CancelledThis study aimed to see if an artificial intelligence system could predict sepsis—a serious infection—in people recovering from abdominal surgery. Researchers planned to use wearable sensors and hospital data to spot early warning signs. However, the study was withdrawn before en…
Sponsor: Aisthesis Medical P.C. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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AI-Powered ECG could spot dangerous potassium shifts without blood draws
Knowledge-focused CancelledThis study planned to use a machine learning algorithm to estimate blood potassium levels from a single-lead ECG in hospitalized patients. It was designed as a retrospective analysis of existing data from a home hospital program. However, the study was withdrawn before enrolling …
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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AI predicts hospital stays, but study never started
Knowledge-focused CancelledThis study aimed to see if a computer could learn to predict how long a patient would stay in a home hospital program. Researchers planned to use data from past patients to train the computer. However, the study was withdrawn before any patients were enrolled, so no results are a…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Swiss study aims to unlock secrets of pandemic spread
Knowledge-focused OngoingThis study follows over 2,000 people and their pets in the Canton of Bern to learn how infections like COVID-19 spread and what social and environmental factors influence transmission. Participants provide samples and answer questionnaires over time. The goal is to improve pandem…
Sponsor: University of Bern • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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New digital tool aims to cut medical errors during hospital transfers
Knowledge-focused By invitation onlyThis study tests a new digital platform that helps doctors and nurses share important patient information when a person is moved from one hospital to another. About 1,000 adults being transferred to a major hospital will take part. The goal is to see if better information sharing…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Massive review of viral meningitis cases aims to sharpen diagnosis
Knowledge-focused OngoingThis study looks back at 4000 patients who had a suspected viral infection of the brain or spinal cord. Researchers will analyze which viruses were found and how the illness progressed in different groups, including children, adults, and people with weakened immune systems. The g…
Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Can listening to mothers prevent sepsis deaths? new study aims to find out.
Knowledge-focused By invitation onlyThis study looks at how social factors like poverty and race affect care for mothers with sepsis, a leading cause of death after childbirth in the U.S. Researchers will interview 200 Spanish- or English-speaking women who recently gave birth and had infection warning signs, plus …
Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Can we predict maternal sepsis? massive study targets racial disparities
Knowledge-focused By invitation onlyThis observational study looks at 400,000 birthing people to better predict maternal sepsis, a leading cause of death in the U.S. The goal is to improve risk prediction by considering social factors like poverty and race, and to create a care model that reduces death and disabili…
Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Pulse power: beans and lentils may reshape your gut bacteria
Knowledge-focused OngoingThis study looks at how eating a diet rich in pulses—like beans, lentils, and peas—affects the gut microbiome, feelings of fullness, and appetite hormones. Researchers are enrolling 44 overweight or obese adults who will follow a high-pulse diet for four weeks. The goal is to see…
Sponsor: University of Missouri-Columbia • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Sweet potato vs. pear: which first food shapes Baby's gut best?
Knowledge-focused OngoingThis study looks at how introducing solid foods like sweet potato or pear changes the gut bacteria of breastfed babies. Researchers will track 102 infants and their mothers to see how these first foods affect digestion, health, and early brain development. The goal is to learn ho…
Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Can a smartphone app unlock the link between infections and FMF attacks?
Knowledge-focused By invitation onlyThis study will enroll 40 children aged 8-18 with Familial Mediterranean Fever (FMF) to see if infections trigger disease flares. Participants will use a mobile app to log symptoms like fever, cough, or sore throat in real time. The goal is to better understand the infection-flar…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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LVAD Patients' infection risks under the microscope
Knowledge-focused OngoingThis study looks at 120 adults getting a left ventricular assist device (LVAD) to see how often infections happen and how their immune system changes after surgery. The goal is to find what makes some patients more likely to get infections. This research does not test a new treat…
Sponsor: China National Center for Cardiovascular Diseases • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Immune cell showdown: autoimmune vs. infection vs. healthy
Knowledge-focused By invitation onlyThis study looks at immune cells from people with autoimmune diseases (like lupus), people with infections, and healthy volunteers. Researchers want to understand how these cells differ and what makes them attack the body in autoimmune conditions. The study involves blood and bon…
Sponsor: Emory University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Can daily supplements ward off infections? huge trial investigates
Knowledge-focused OngoingThis study looks at whether taking vitamin D and omega-3 (fish oil) supplements can lower the risk of infections like colds, flu, and urinary tract infections in healthy adults. It also measures a protein called hCAP18, which is part of the body's natural defense against germs. O…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC