Could a sprinkle of antibiotic powder in joint surgery stop infections?
NCT ID NCT04399642
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at whether putting vancomycin powder directly into the joint during hip or knee replacement surgery can prevent infections better than standard IV antibiotics alone. About 1,800 adults having primary or revision joint replacement are being followed for two years. The goal is to see if the extra powder reduces infection rates after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- vancomycin powder
- What this could lead to
- If it works, this could provide a simple, low-cost way to reduce infections after joint replacement surgery, potentially improving recovery and reducing complications.
- What could go wrong
- This is a single study with results not yet reported. The added antibiotic may not lower infection rates and could carry risks like allergic reactions or antibiotic resistance.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hopital Sacré-Coeur de Montreal
Montreal, Quebec, H4J 1C5, Canada
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