Tetanus
MONDO:0005526A serious infectious disorder that follows wound contamination by the Gram-positive bacterium Clostridium tetani. The bacteria produce a neurotoxin called tetanospasmin, which causes muscle spasm in the jaw and other anatomic sites.
Also known as: Clostridium tetani caused infectious disease of the nervous system, Clostridium tetani infectious disease of the nervous system, lockjaw
37 clinical trials for this condition and its sub-types.
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Broader categories
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One shot to rule them all? new combo vaccine trial for kids begins
⭐️ VACCINE ⭐️ Recruiting nowThis early-stage trial is testing a new vaccine that combines protection against several serious childhood diseases: diphtheria, tetanus, whooping cough, meningitis, and Hib. The study involves 260 children aged 2 months to 6 years to check the vaccine's safety and immune respons…
Phase: PHASE1 • Sponsor: CanSino Biologics Inc. • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 08:07 UTC
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One shot in pregnancy could shield babies from whooping cough
Prevention Recruiting nowThis phase 3 trial will give a single dose of the dTpa vaccine (Boostrix) to 95 healthy Japanese pregnant women between 27 and 37 weeks of pregnancy. The goal is to see if the vaccine triggers strong immunity in the mothers and passes protective antibodies to their babies at birt…
Phase: PHASE3 • Sponsor: GlaxoSmithKline • Aim: Prevention
Last updated Jul 30, 2026 00:00 UTC
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New shot aims to block tetanus after cuts and wounds
Prevention Recruiting nowThis study tests a new medicine called siltartoxatug to prevent tetanus in people who have been injured. About 6,000 adults in China will receive either the new drug or a standard tetanus shot. Researchers will check how well each treatment prevents tetanus over 90 days and monit…
Sponsor: Zhuhai Trinomab Pharmaceutical Co., Ltd. • Aim: Prevention
Last updated Jul 29, 2026 00:00 UTC
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New tetanus shot under study in 10,000 people
Prevention Recruiting nowThis large real-world study is testing an injection called siltartoxatug (Sintetol®) to prevent tetanus in people who have been injured. Researchers will follow 10,000 participants for 90 days to see if the shot prevents tetanus and to track any side effects. The goal is to learn…
Sponsor: Zhuhai Trinomab Pharmaceutical Co., Ltd. • Aim: Prevention
Last updated Jun 27, 2026 08:09 UTC
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Can we better predict tetanus death risk?
Knowledge-focused Recruiting nowThis study looks at three different scoring systems to see which one best predicts the risk of death in patients with severe tetanus in the intensive care unit. Researchers will follow 115 adults with tetanus for up to 90 days. The goal is to find the most accurate tool to help d…
Sponsor: Ain Shams University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:39 UTC
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Web lessons aim to boost vaccine knowledge in pregnant women
Knowledge-focused Recruiting nowThis study tests whether a web-based educational program can improve pregnant women's knowledge about influenza and Tdap vaccines and increase their intention to get vaccinated. Researchers will compare the program to standard antenatal care in 351 pregnant women in Malaysia. Par…
Phase: NA • Sponsor: Universiti Putra Malaysia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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10,000 people tested: Cambodia's massive disease hunt begins
Knowledge-focused Recruiting nowThis study will test 10,000 people in Cambodia for 57 different infectious diseases, including dengue, flu, and malaria. Researchers want to understand how these diseases spread and who is at risk. The goal is to give local health authorities the information they need to create b…
Sponsor: Institut Pasteur du Cambodge • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC