New shingles vaccine shows promise in Head-to-Head trial

NCT ID NCT06581575

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new shingles vaccine called JCXH-105 in healthy adults aged 50 and older. It compares the new vaccine to the current standard, Shingrix, to see if it is safe and triggers a strong immune response. About 467 participants will receive either JCXH-105 or Shingrix, and researchers will monitor side effects and immune markers over several months.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • DM Clinical Research - Chicago

    Chicago, Illinois, 60652, United States

  • DM Clinical Research - New Jersey

    Jersey City, New Jersey, 07306, United States

  • DM Clinical Research - Sugarland

    Sugar Land, Texas, 77478, United States

  • Delricht Research

    Charleston, South Carolina, 29407, United States

  • Delricht Research

    Prosper, Texas, 75078, United States

  • Long Beach Research Institute

    Long Beach, California, 90805, United States

  • Noble Clinical Research

    Tucson, Arizona, 85704, United States

  • Quality Clinical Research

    Omaha, Nebraska, 68114, United States

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