Protein-Packed breast milk could help tiny preemies grow stronger

NCT ID NCT04325308

First seen Jun 26, 2026 · Last updated Jun 30, 2026 · Updated 2 times

Summary

This study tests whether adding extra protein to breast milk during the first two weeks of life helps extremely preterm infants (born at 28 weeks or earlier) gain more lean body mass and develop a healthier gut microbiome. About 150 babies will be randomly assigned to receive either protein-enriched human milk or standard human milk. The goal is to see if the extra protein improves growth and gut bacteria diversity by the time they reach their original due date.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

human-based protein supplement added to human milk

What this could lead to

If it works, this could improve growth and gut health in extremely preterm infants, reducing long-term health problems.

What could go wrong

This is an early-stage trial with only 150 infants, so results may not apply to all preterm babies. Adding protein may also cause digestive issues or other side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Breast Milk Expression Failure to Thrive infectious disease Premature Birth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35233, United States