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Could simple mouth care prevent lung infections in preemies?

NCT ID NCT05167318

Ongoing Disease control Sponsor: University of Florida Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether cleaning the mouth of very premature infants every 3-4 hours can reduce harmful bacteria and lower the risk of pneumonia and other breathing problems. Researchers will follow 40 infants born before 32 weeks and weighing less than 1500 grams, comparing two different schedules of oral care. The goal is to see if more frequent care is feasible and improves health outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
standardized oral care
What this could lead to
If it works, this could lead to a simple, low-cost way to reduce pneumonia and chronic lung disease in premature infants.
What could go wrong
This is a small, early feasibility study with only 40 infants, so results may not be conclusive or apply to all hospitals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

infectious disease Pneumonia, Ventilator-Associated

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MICROBIAL COLONIZATION VENTILATOR ASSOCIATED PNEUMONIA

Contacts and locations

Locations

  • University of Florida

    Gainesville, Florida, 32610, United States

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