SARCOPENIA

This study is testing a new clinic designed to find and treat muscle loss (sarcopenia) in people with COPD. About 80 adults who have been hospitalized for COPD will join. The clinic uses CT scans to check muscle mass and offers a team approach with a lung doctor, pharmacist, and …

This study tests a 12-week exercise program for adults aged 45 to 85 who have both type 2 diabetes and sarcopenia (age-related muscle loss). The program combines supervised and home-based exercises with digital support to improve muscle function, physical performance, and blood s…

This study tests whether adding a blood-filtering device called CytoSorb to standard care helps people with acute-on-chronic liver failure. It involves 20 adults whose liver suddenly worsens, causing high bilirubin and confusion. The device aims to remove toxins from the blood ov…

This study looks at whether adding electrical muscle stimulation (EMS) to lower-body resistance training helps postmenopausal women more than exercise alone. About 39 women aged 50–70 who don't currently exercise will be split into three groups: EMS plus exercise, exercise only, …

This study looks at whether taking creatine supplements while doing supervised resistance training for 12 weeks can help men with prostate cancer who are on hormone therapy (ADT) maintain or improve muscle mass, strength, and physical function. ADT often causes muscle loss and we…

This study looks at whether taking vitamin D supplements after surgery can help keep muscles healthy. Vitamin D is important for bone and muscle health, and low levels can slow muscle recovery. The trial will enroll 100 adults aged 21-65 who have low vitamin D after surgery and w…

This study tests whether a traditional Chinese medicine (TCM) formula can improve muscle strength and bone health in older adults who are starting to become frail. 90 people aged 65 and older who are pre-frail will be randomly assigned to take either the TCM formula or a nutritio…

This study looks at 164 adults with cirrhosis (scarred liver) who also have severe muscle loss (sarcopenia) and need a procedure called TIPS to treat complications like bleeding. Half will get TIPS alone, and half will get TIPS plus branched-chain amino acid (BCAA) supplements. T…

This study looks at whether a daily, gentler form of dialysis (low dialysate flow) combined with exercise and nutrition counseling can help kidney patients recover muscle strength and function after a serious illness. About 50 adults with end-stage kidney disease who were recentl…

This study looks at whether a virtual group exercise program combined with health education can lower fall risk and increase physical activity in older Veterans who have obesity and signs of muscle loss (sarcopenia). About 50 Veterans aged 55 and older will take part. The goal is…

This study is testing whether eating protein evenly throughout the day combined with exercise can improve nutrition, muscle mass, and physical function in 90 adults waiting for a liver transplant. Participants are randomly assigned to one of three groups: even protein distributio…

This study tests whether a drug called nandrolone decanoate, combined with physical therapy and a special diet, can help older adults with sarcopenia (age-related muscle loss) regain strength and mobility. About 168 people aged 60 to 99 will receive either the drug or a placebo, …

This study tests whether taking creatine HCl daily for 12 weeks can improve muscle strength, physical function, and brain performance in adults over 60 with sarcopenia (age-related muscle loss). Researchers will also check changes in blood markers and tissue creatine levels. The …

This study aims to improve how doctors diagnose sarcopenia—a condition where older adults lose muscle mass and strength, raising their risk of falls and disability. Researchers will test a new, non-invasive technology (HD-sEMG) that measures muscle signals in 846 people aged 75 a…

This study compares using a tape measure around the calf to a standard X-ray method for diagnosing sarcopenia (age-related muscle loss) in hospitalized patients aged 75 and older. Researchers will enroll 298 participants to see if the simple calf measurement is accurate enough to…

This study tests a 12-week program delivered through a smartphone app (Line Bot) that provides personalized exercise videos, nutrition tips, and daily reminders. Researchers want to see if this technology-based approach can help 60 older adults at risk of sarcopenia improve muscl…

This study looks at whether taking krill oil for 6 months can increase muscle strength and improve walking in healthy adults aged 65 and older. Researchers will measure grip strength, leg muscle size, and how well nerves control muscles. The goal is to find out if a simple supple…

This study looks at whether high-intensity interval training (short, intense exercise bursts) or moderate-intensity continuous training (steady, moderate exercise) better helps stroke survivors who have lost muscle mass. Researchers will measure changes in muscle thickness, stren…

This study tests whether adding electroacupuncture (a gentle electric needle therapy) to standard rehabilitation exercises can improve walking ability in older adults with sarcopenia (age-related muscle loss). About 120 people aged 60–95 will be randomly assigned to receive eithe…

This study tests a device that sends mild electrical pulses to the thigh muscles of people in the ICU. The goal is to see if it is safe and practical to use, and whether it can slow down muscle weakening. About 50 critically ill patients will either receive standard care or stand…

This small study tests whether a supervised exercise program can help children and teens (ages 5-17) with acute lymphoblastic leukemia maintain or regain muscle strength during early treatment. Researchers will monitor kids who show signs of weakness after 5 weeks of chemotherapy…

This study tests whether a 12-week supervised exercise program during dialysis can help patients over 40 with chronic kidney disease build muscle, improve sleep, and feel better overall. Half of the 58 participants will do strength and aerobic exercises during their first 90 minu…

This study tests a digital therapeutic device designed to help people with sarcopenia (age-related muscle loss) build stronger muscles. About 130 participants will either use the device or do self-exercises at home. The main goal is to see if the device improves knee strength mor…

This study tests whether a program of exercise, nutrition advice, and geriatric care before surgery can help adults aged 65+ with breast cancer maintain physical function and reduce complications. About 90 participants will follow the 8-week program, and researchers will track ch…

This study is testing whether a pulmonary rehabilitation program can help people with advanced non-small-cell lung cancer maintain muscle mass, improve lung function, and reduce inflammation. About 94 participants will take part while receiving standard cancer treatments like che…

This study tests whether a daily powder made from silkworm pupae can improve nutrition, muscle strength, and quality of life in people with Alzheimer's disease. Two hundred participants will take either the powder or a placebo for three months, with regular checkups. The goal is …

This study tests whether taking essential amino acids and doing exercise can improve muscle strength and function in people on dialysis who have muscle loss (sarcopenia). About 40 participants will be randomly assigned to receive the supplement plus exercise or standard care. The…

This study tests whether a 6-week supervised pool exercise program can improve muscle strength, muscle mass, physical performance, and quality of life in adults aged 65 and older with sarcopenia (age-related muscle loss). Participants will exercise in water, which is easier on jo…

This study looks at whether a supervised exercise program with resistance training and relaxation can improve muscle mass and quality of life in women who have finished breast cancer treatment. About 66 participants will either join a therapist-led program at a facility or do exe…

This study tests whether eating 12 grams of a special oil (high in linoleic acid) every day can help older adults with muscle loss (sarcopenia) improve their strength, muscle size, and mobility. Researchers will compare the oil to a placebo over time. The goal is to find a simple…

This study explores whether taking a daily polyphenol supplement (natural compounds found in plants) alongside a 12-week exercise program can help older adults build strength and physical function better than exercise alone. Researchers will recruit 40 people over 60 to test if t…

This study looks at whether whole body vibration therapy, when added to usual care, can improve muscle mass, strength, and function in older adults. Forty people aged 65 and older with mild frailty will be randomly assigned to receive vibration therapy plus usual care or usual ca…

This study looks at why older adults respond differently to the same exercise program. Researchers will measure fitness, muscle strength, and balance in 250 healthy adults aged 60 and older who have not been exercising regularly. The goal is to understand these differences and ev…

This study looks at why people with chronic kidney disease (CKD) often lose muscle mass and strength, a condition called sarcopenia. Researchers will follow 1,000 adults with CKD to find risk factors for sarcopenia and see how it relates to worse health outcomes like disease prog…

This study watches how sarcopenia (muscle loss) and frailty affect the way a muscle relaxant called rocuronium works in older patients having planned surgery. About 100 people aged 65 and older will take part. The goal is to learn if these conditions change how fast the drug work…

This study looks at how nutrition and body composition (like muscle and fat) impact the health of people with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. Researchers will follow 300 participants starting new medical treatments or having sur…

This study aims to find out how many adults visiting hospital clinics in Turkey are at risk for malnutrition and sarcopenia (muscle loss). Researchers will use a simple questionnaire and measure things like weight, calf size, and hand grip strength. No treatment is given—this is …

This study tracks 60 people with liver cirrhosis to see how common muscle loss (sarcopenia) is and how it changes over time. Researchers use ultrasound to measure muscle size and a grip test to check strength. They also look at nutrition's role. The goal is to better understand m…

This study looks at whether easy-to-do tests for muscle strength and frailty can help predict complications after major abdominal surgery in people aged 65 and older. About 100 participants will complete brief assessments during a routine pre-surgery visit, and researchers will c…

This study looks at how a person's muscle and fat levels affect the side effects of chemotherapy for advanced lung cancer. Researchers want to see if adjusting the chemo dose based on body composition can reduce toxicity. About 132 patients will be followed to track side effects …

This study is following 10,000 adults aged 18 and older to learn how muscle loss (sarcopenia), metabolic diseases, and aging are connected. Researchers will collect health data, lifestyle info, and biosamples over time. The goal is to understand how these factors together affect …

This study looks at the gut bacteria of older adults with sarcopenia (age-related muscle loss) and compares them to healthy older and young adults. The goal is to find differences that could help create probiotics to treat sarcopenia. 150 people aged 65-90 with sarcopenia will pa…

This study looks at whether a 2-week exercise and nutrition program before head and neck cancer surgery is safe and doable. About 20 adults with a new head and neck cancer diagnosis will take part. The goal is to see if patients can complete the program and if they find it accept…

This study looks at whether pregnant women with gestational diabetes also have sarcopenia (loss of muscle mass and strength). Researchers will check 200 women for muscle health and follow their pregnancy outcomes. The goal is to understand how common this muscle problem is and if…

This small pilot study looks at whether whole-body electrical muscle stimulation (WB-EMS) combined with exercise can improve how nerves activate muscles in healthy older adults. Twelve participants will undergo testing before and after four weeks of twice-weekly WB-EMS sessions. …

This study is for older adults with advanced colorectal cancer who are about to start chemotherapy. It aims to find out if having low muscle mass at the start of treatment leads to more severe side effects. Researchers will track side effects and survival over at least one year. …

This study looks at whether age-related muscle loss, called sarcopenia, is linked to the type and location of rotator cuff tears in the shoulder. Researchers will measure muscle strength and thigh thickness in 104 adults aged 40-75 with shoulder problems. They will then compare s…

This study aims to better understand sarcopenia (muscle loss) in people with heart failure. Researchers will use special MRI scans to measure muscle properties in 70 participants—some with heart failure and sarcopenia, some without. No treatments or drugs are tested; the goal is …

This study is enrolling 20,000 adults in Taining County, China, to better understand chronic diseases like high blood pressure, diabetes, and frailty. Researchers will collect health data and samples over three years to find patterns and risk factors. The goal is to create a bett…

This study aims to make sure lab tests, equipment, and procedures used in research on obesity, diabetes, heart disease, and bone disorders are accurate and give consistent results. It will involve up to 100 healthy volunteers and people with these conditions, aged 18 to 100. The …

This study looks at how two types of anesthesia (total intravenous vs. inhaled) affect muscle loss in 40 adults undergoing colorectal cancer surgery. Researchers will measure muscle mass and strength before and after surgery using ultrasound, grip strength tests, and body composi…

This study looks at whether giving older adults with sarcopenia (age-related muscle loss) real-time feedback on how fast they move during leg presses can improve muscle activation and motivation. Sixty participants aged 60-95 will visit the lab once a week for three weeks to do l…

This study will follow 5,000 middle-aged and older Tzu Chi volunteers in Taiwan to see how vegetarian and plant-based diets affect healthy aging. Researchers will measure thinking skills, muscle mass, grip strength, and signs of frailty. The goal is to learn which eating patterns…

This study looks at muscle loss (sarcopenia) and cognitive problems (chemobrain) in people who have finished cancer treatment. Researchers will collect data from 100 adults aged 18-74 with certain cancers to see how common these issues are. The goal is to better understand and ma…

This study follows 100 women with early-stage breast cancer for two years after surgery and other treatments. Researchers will measure changes in muscle mass and body fat to understand how the body recovers. The goal is to learn more about long-term health and quality of life aft…

This study checks how many people with gastrointestinal cancer are at risk for sarcopenia—a condition where muscles weaken and shrink. Researchers will use a simple questionnaire (SARC-F) before and during cancer treatment. The goal is to find those at risk early so they can get …

This study follows 142 adults having lung cancer surgery to see if measuring nutrition and muscle loss can predict complications like infections or long hospital stays. Participants get blood tests, CT scans, and ultrasound before surgery. The goal is to create a risk score to he…

This study looks at why a procedure called TIPS, which helps lower blood pressure in the liver, may also improve muscle loss (sarcopenia) in people with advanced liver disease. Researchers will measure a protein called FGF21 and muscle mass in 132 adults with cirrhosis before and…

This study looks at how diet and gut bacteria are linked to sarcopenia, the age-related loss of muscle mass and strength. Researchers will analyze the eating habits and gut microbes of 1,220 adults aged 60 and older. The goal is to understand if certain diets that cause inflammat…

This study looks at how well a new type of whey protein, called 'super-whey', helps older adults build muscle. Researchers will give 30 participants different doses of the protein and measure muscle growth at rest and after exercise. The goal is to find the best dose to fight age…

This study follows 250 adults in the intensive care unit (ICU) to learn why some become frail and lose muscle. Researchers will track hospital stays, falls, and readmissions to find factors that can be changed. The goal is to identify targets for future treatments to help patient…