SARCOPENIA

This study involved 60 adults with advanced esophageal cancer who were scheduled for chemotherapy and surgery. Some received a feeding tube early, at the time of diagnosis, while others got it later during surgery. The goal was to see if early tube feeding helps prevent muscle lo…

This study tests whether taking branched-chain amino acids (BCAAs) for 24 weeks can help people with liver cirrhosis who have low muscle mass regain muscle and improve strength. About 86 adults aged 18-85 will receive either BCAA supplements or a placebo, along with diet and exer…

This study looks at whether taking creatine and HMB supplements, combined with a supervised exercise program, can improve physical function, muscle mass, thinking skills, and quality of life in older adults living in nursing homes who are frail or have muscle loss. Fifty people a…

This study looks at whether eating biscuits made with pea protein and taking vitamin D can slow down sarcopenia, the loss of muscle mass and strength that often happens as we age. Researchers will recruit 74 adults aged 65-80 with sarcopenia. For 12 weeks, some will eat the speci…

This program provides expanded access to an experimental treatment (IMM01-STEM) for people with sarcopenic obesity—a condition where muscle loss and excess body fat occur together. It is designed for patients who cannot join other clinical trials due to location, eligibility, or …

This study looks at whether giving extra nutrition through a vein during dialysis (called IDPN) helps kidney patients maintain muscle mass and improve their quality of life. About 166 adults on long-term dialysis will receive IDPN or standard care. The main goal is to see if it p…

This study tests whether 12 months of high-intensity strength training can reduce falls in people aged 80 and older who have sarcopenia (age-related muscle loss). About 241 participants will either do progressive resistance exercises or be in a control group. The goal is to see i…

This study looks at whether a daily supplement called nicotinamide riboside (a form of vitamin B3) can improve muscle strength, walking speed, and endurance in older veterans aged 65 to 85. The researchers will measure changes in fitness and muscle health over time. The goal is t…

This study looks at whether a group exercise program using videos is safe and practical for people receiving hemodialysis. 45 adults on dialysis will try the program during their sessions. The goal is to see if it helps prevent muscle loss and improve physical function, without c…

This study tests whether a 12-week exercise program during dialysis can improve muscle health and dialysis effectiveness in people with advanced kidney disease and muscle loss. About 40 participants will either exercise three times a week during dialysis or receive standard care.…

This study looks at whether a 12-week program of functional task training (like standing up from a chair, climbing stairs, and carrying objects) can improve muscle mass, strength, and daily function in older adults with sarcopenia. 30 people aged 60 and older will be randomly ass…

This study looks at whether online exercise programs supervised by physical therapists can help people with chronic kidney disease improve muscle strength and function. Researchers will also check if the tools used to measure strength are reliable. About 50 adults with CKD (on di…

This study tests whether artificial intelligence (AI) can better predict who is at risk for sarcopenia—age-related muscle loss that can lead to frailty and disability. Researchers will first analyze data from 3,500 adults to build a risk model, then test a personalized 12-week ex…

This study is looking at whether having low muscle mass (sarcopenia) before lung cancer surgery affects how well patients recover. Researchers are following 400 older adults to see if muscle loss is linked to survival and cancer return. The goal is to find out if checking muscle …

This study looks at why many people with heart failure also lose muscle mass and strength, a condition called sarcopenia. Researchers will measure muscle mass, walking speed, and grip strength, and analyze blood samples from 80 participants aged 50 and older. The goal is to find …

This study looks at muscle and fat in people with chronic kidney disease (CKD) compared to healthy volunteers. The goal is to understand how and when muscle loss happens in CKD, which could help design future treatments to improve quality of life. About 80 adults with CKD stages …

This study measures how much force the leg joints (hip, knee, ankle) can produce and how muscles use oxygen in people with stroke or sarcopenia (age-related muscle loss). Researchers compare these measurements to healthy adults to understand what kind of help patients need when w…

This study looks at 200 adults with solid tumors who are getting chemotherapy. Researchers will compare four different checklists (PG-SGA, MUST, Nutriscore, and GLIM criteria) to see which one best identifies malnutrition and muscle loss. The goal is to find the most reliable too…

This study aims to establish normal muscle mass values for the Turkish population using a special X-ray scan. Sarcopenia is a condition where people lose muscle and strength, raising the risk of falls and disability. By measuring muscle in healthy young and older adults, research…

This study re-examines 317 adults with type 2 diabetes who were first checked between 2019 and 2023. Researchers use advanced scans and blood tests to see how many have fatty liver disease (MASLD) and whether it has gotten better or worse over time. The goal is to learn what fact…

This study looks at whether medications for osteoporosis also improve muscle health in adults aged 65 and older who have both bone loss and muscle loss (sarcopenia). Researchers will measure changes in muscle mass, strength, walking speed, and bone density over time. The goal is …

This study looks at whether breast cancer patients lose muscle outside the radiation area and if that loss is linked to fatigue. Twenty women will complete fatigue questionnaires and get CT scans before, during, and after radiotherapy. The goal is to understand how radiation affe…

This study aimed to see if a 6-month nutrition plan could improve weight and strength in malnourished older adults compared to standard hospital care. It was designed for people aged 65 and older in Italian hospitals. However, the study was withdrawn before enrolling any particip…

This study looks at how many adults in the intensive care unit (ICU) who need a breathing machine for more than 48 hours have muscle loss (sarcopenia). Researchers will use simple tests like questionnaires, body composition scans, and ultrasound to measure muscle. They will also …

This study looks at whether watching short, educational videos (nano-learning) can help older adults with sarcopenia (age-related muscle loss) stick to diet and exercise advice and improve their mood. Researchers are testing this approach with 180 people aged 60 and older in a ru…