SARCOPENIA

This study tests a 12-week resistance exercise program designed to help older adults with sarcopenia (age-related muscle loss) improve muscle mass, strength, and physical function. About 90 participants will be randomly assigned to start the program right away or wait 3 months be…

This study tests whether a volunteer-led lifestyle program, supported by a digital tool, can improve muscle mass, strength, and mobility in older adults (60+) who have or are at risk for sarcopenia (age-related muscle loss). The program includes exercise and nutrition guidance de…

This study looks at whether taking magnesium supplements can improve muscle strength, muscle mass, and physical performance in older adults with sarcopenia (age-related muscle loss). Researchers will enroll 352 people aged 70 and older from Portugal. Participants with low magnesi…

This study tests a combination of high-protein supplements, mobility-based physical therapy, and neuromuscular electric stimulation in older adults (60+) who have been in the ICU for at least two weeks and now have muscle weakness. The goal is to see if this approach can improve …

This study tests whether a traditional Chinese medicine formula, Huangjing Yangji, combined with resistance band exercises, can improve physical function and muscle strength in older adults with sarcopenia (age-related muscle loss). About 106 participants will take either the her…

This study tests personalized diet and exercise plans to help adults aged 50-75 with obesity lose weight while keeping muscle. Participants will follow different protein and exercise routines over 52 weeks. The goal is to find the best approach for healthy weight loss in older ad…

This study tests whether specially designed, shelf-stable meals can improve muscle health, thinking skills, and nutrition in low-income older adults in Malaysia. About 70 people aged 60-84 who are at risk of food insecurity will receive these meals for 12 weeks. Researchers will …

This study looks at whether roxadustat, a drug used to treat anemia in kidney disease, can also help reduce muscle loss (sarcopenia) in people on hemodialysis. About 60 adults with end-stage kidney disease and anemia will receive either roxadustat or a standard treatment. Researc…

This study tests whether walking in a robotic exoskeleton combined with mild electrical stimulation of the spinal cord can improve muscle and bone health in people with chronic spinal cord injury. Twenty-four participants will be randomly assigned to receive either real or sham s…

This study aims to create a smart AI tool that can diagnose sarcopenia—age-related muscle loss—by combining muscle function tests and imaging data. Researchers will also see if a rehabilitation exercise program can help slow or reverse muscle aging. The study involves 75 adults a…

This study tests whether adding neuromuscular electrical stimulation (NMES) to resistance exercises can improve muscle strength and physical function in hospitalized adults aged 47–70 with alcoholic liver cirrhosis and sarcopenia (muscle loss). Participants will be randomly assig…

This study looks at whether a special exercise program (phase I cardiac rehabilitation) can improve muscle strength and reduce inflammation in elderly people who have both heart disease and muscle loss (sarcopenia). About 100 participants will either get the rehab program plus st…

This study tests whether personalized cooking and food guidance can help slow muscle loss and improve quality of life in adults with advanced cancer who are on chemotherapy. About 200 participants will be split into two groups: one gets standard nutrition care plus exercise advic…

This study tests whether a 32-week multicomponent exercise program can improve muscle quality, strength, and physical function in women over 60 with sarcopenia (age-related muscle loss). Researchers will use ultrasound to measure changes in muscle structure and body composition. …

This study tests whether a supervised exercise program can improve muscle strength, muscle mass, and physical performance in women with cancer-related sarcopenia (muscle loss). Researchers will enroll 78 women who have completed primary cancer treatment and have low muscle streng…

This study tests whether a supplement made from apple pomace (a byproduct of apple processing) can improve muscle strength and physical performance in older adults with mild sarcopenia, a condition that causes age-related muscle loss. About 105 people aged 65-80 will take either …

This study tests whether a digital prehabilitation app (HEAL-ME) combined with creatine and whey protein supplements can help maintain muscle health and reduce frailty in 100 adults with cirrhosis. Participants will use the app and take supplements for at least 3 months. The goal…

This study looks at whether using a health app for symptom tracking plus doing resistance exercises can improve quality of life and reduce muscle loss in people who had surgery for esophageal cancer. About 90 adults who have fully recovered from surgery will take part. The goal i…

This study tests a 6-week program that combines group reading discussions with simple mouth exercises for adults aged 55 and older. The goal is to see if this non-drug approach can reduce depression, improve physical and oral health, and boost mental toughness. 60 participants wi…

This study tests whether two types of amino acid supplements can safely improve muscle mass and strength in people with advanced chronic kidney disease who also have muscle loss (sarcopenia). About 20 adults aged 45–75 will take the supplements for 6 weeks each. The goal is to fi…

This study will test whether interactive, game-based exercises (exergames) can improve foot muscle function, balance, and mobility in older adults. Forty healthy seniors aged 65-80 will be randomly assigned to either exergame training or standard balance exercises for 8 weeks. Re…

This study looks at whether a 12-week strengthening exercise program, done either in person or at home, can improve muscle strength, muscle mass, and thinking abilities in adults with compensated liver cirrhosis. Twenty participants aged 40-65 will be randomly assigned to one of …

This study tests whether an 8-week tele-rehabilitation program can improve muscle mass, reduce frailty, and enhance quality of life in adults with cystic fibrosis. Participants will do supervised exercise sessions at home via video calls three times a week. The goal is to see if …

This study tests a 12-week home-based exercise program for adults aged 60+ with type 2 diabetes and early muscle weakness (probable sarcopenia). Participants will do short bouts of aerobic and resistance exercises to see if it improves their physical activity levels and muscle st…

This study tests a home strengthening program for adults aged 65 and older who have sarcopenia (muscle loss) or frailty. Participants use a Bluetooth-connected resistance band and app that gives real-time feedback, while a doctor monitors progress remotely. The goal is to see if …

This study looks at whether two different exercise programs can improve physical function, balance, and mental well-being in older adults aged 60 and over living in Angola. A total of 350 participants will be randomly assigned to either a multicomponent exercise program or a simp…

This study looks at whether a CT scan already done for routine care can predict which patients with leg artery disease will improve with supervised exercise. About 40% of patients don't get enough benefit from exercise and need a procedure to open blocked arteries. Researchers wi…

This study looks at 100 elderly patients with hip fractures to see if quick, easy tests like ultrasound muscle measurements, handgrip strength, and routine blood work can predict frailty. Frailty affects recovery after surgery, so finding a fast way to measure it could help docto…

This study looks at how muscle loss (sarcopenia) affects recovery in people aged 80 and older hospitalized for acute heart failure. Researchers will use ultrasound, strength tests, and blood markers to better predict outcomes like rehospitalization or death. The goal is to improv…

This study checks if a computer program called Soma can correctly measure muscle and fat from CT scans. Researchers will compare Soma's results to measurements made by three expert radiologists using 200 CT scans from public databases. The goal is to see if the software is accura…

This study looks at how muscle loss (sarcopenia) is related to tiredness and dizziness when standing up in people aged 65 and older. Researchers will compare two groups: those with sarcopenia and those without. The goal is to better understand these connections to improve care fo…

This study looks at whether combining simple tests—like handgrip strength, body composition analysis, and thigh ultrasound—can help doctors spot rapid muscle loss (acute sarcopenia) in older adults admitted to the hospital. Researchers will follow 280 patients aged 65 and older t…

This study looks at whether a new, painless ultrasound method can measure fat inside the muscles of older adults (75+) who are in a rehabilitation program after a hospital stay. The goal is to see if having more fat in the muscles makes it harder to regain physical strength and m…

This study looks at how many people with knee osteoarthritis also have sarcopenia, a condition where muscles become weak and shrink. Researchers will check muscle mass, strength, and physical performance in 224 adults aged 40 and older in Upper Egypt. The goal is to better unders…

This study looks at whether a blood test measuring the ratio of two substances (IGF-1 and albumin) can help identify muscle loss severity in people with end-stage kidney disease on dialysis. About 110 adults will have their blood tested and compared to standard muscle assessments…

This study explores why childhood cancer survivors often lose muscle mass and strength earlier than normal, which can lead to health problems. Researchers will use advanced scans and muscle tests to identify different types of muscle decline in 533 adult survivors and compare the…

This study aims to find out how common muscle loss (sarcopenia) is in people aged 60 and older who have had type 2 diabetes for at least 5 years. Researchers will use ultrasound and grip strength tests to measure muscle health and a questionnaire to see how muscle loss affects qu…

This study looks at how HIV might speed up aging. Researchers will compare frailty, muscle loss, nutrition, thinking, and physical function in 80 adults aged 40 and older—half with HIV and half without. The goal is to understand if people with HIV face these age-related problems …

This study observes 30 adults in Mexico who are already taking tirzepatide for conditions like diabetes or obesity. Researchers will use MRI scans, heart CT scans, and body composition tests to see how the drug affects knee cartilage, heart fat, and overall body health over one y…

This study looks at whether older adults (70+) with low muscle mass have a higher risk of bleeding while taking common blood thinners. Researchers will compare muscle mass, sarcopenia, and nutrition between 110 patients who had a bleeding event and those who did not. The goal is …

This is a randomized, double-blind, placebo-controlled, parallel-group, prospective, multi-center clinical trial, to evaluate the efficacy of silkworm pupa tablets in improving nutritional status and sarcopenia in patients with malignancies who have completed comprehensive treatm…