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Can a Muscle-Zapping device help cirrhosis patients get stronger?

NCT ID NCT07162636

Symptom relief Sponsor: Hospital Universitário Professor Edgard Santos Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 2 times

Summary

This study tests whether adding neuromuscular electrical stimulation (NMES) to resistance exercises can improve muscle strength and physical performance in hospitalized patients with alcoholic liver cirrhosis who have muscle loss (sarcopenia). About 112 participants aged 47–70 will be randomly assigned to receive either NMES plus exercise or exercise alone, six times per week during their hospital stay. Researchers will measure handgrip strength and sit-to-stand tests at admission and discharge to see if the combination therapy works better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
neuromuscular electrical stimulation (NMES) combined with resistance exercise
What this could lead to
If it works, this could provide a better rehabilitation method to help hospitalized patients with alcoholic liver cirrhosis regain muscle strength and reduce hospital readmissions.
What could go wrong
This is a small early-stage trial with only 112 participants, so results may not apply broadly. The intervention is physical therapy, not a drug, so benefits may be modest and depend on patient adherence.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 112 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2025

An estimate. Start dates often move.

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

47 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Hospitalized participants with alcoholic cirrhosis. Exclusion Criteria: * Five times sit-to-stand test (5xSTS) below the reference value according to the equation 5xSTS = 3.89 + (0.10 x age). * Handgrip strength test (HGS) below 27Kgf for men and 16Kgf for women.

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Conditions

The condition(s) this trial relates to.

alcoholic liver cirrhosis cirrhosis of liver Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Liver cirrhosis Sarcopenia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

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Other studies related to the condition(s) this trial covers.