Chef-Approved diet may help cancer patients keep muscle and strength
NCT ID NCT07466862
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether personalized cooking and food guidance can help slow muscle loss in people with advanced cancer who are on chemotherapy. About 200 adults will be split into two groups: one gets standard nutrition care plus exercise advice, and the other gets the same plus tailored meal plans based on their taste and smell changes. The goal is to see if this approach helps maintain muscle mass, strength, and quality of life during treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 200 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Ambulatory males and females, age ≥ 18 years * Performance status (PS) 0-2 * Patients with non-occlusive, metastatic malignancies of the gastrointestinal, lung, genitourinary, or breast origin (stage 4) * Receiving/about to receive chemotherapy treatment * Have an estimated life expectancy of at least 6 months * At least 4 weeks post major surgery * Mild to moderate muscle mass loss based on the SMI measure on compoCT * At risk of malnutrition according to the 'Malnutrition Universal Screening Tool' (MUST) (Score ≥2) * Able to understand and provide written informed consent * Willing and able to complete all study-specific procedures and visits * Willing and able (either personally or with the help of family members) to prepare meals according to the adjusted recipes Exclusion Criteria: * Patients suffering from gastrointestinal obstruction * Patients with severe dietary restrictions * A medical condition that impacts the ability to increase muscle mass, as per the PI decision * Uncontrolled thyroid disease * Self-reported major dietary restrictions related to the intervention, such as irritable bowel syndrome (IBS) * Patients with a history or active eating disorder * Pregnant or lactating
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Davidoff Center of Cancer, Rabin Medical Center
Petah Tikva, 49100, Israel
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Other studies related to the condition(s) this trial covers.
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