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Could muscle loss weaken the power of nerve blocks?

NCT ID NCT07757984

Knowledge-focused Sponsor: Chang Gung Memorial Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time

Summary

This study looks at whether sarcopenia—age-related muscle loss—changes how well regional nerve blocks work for people having upper limb surgery. Researchers will compare patients with and without sarcopenia, measuring how quickly the block takes effect, how well it controls pain, and how much pain medication is needed after surgery. The goal is to understand if muscle loss affects anesthesia and recovery, which could help tailor pain management for older adults.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Regional nerve block combined with general anesthesia
What this could lead to
If muscle loss affects nerve block performance, this could lead to tailored anesthesia plans that improve pain control and recovery for older adults with sarcopenia.
What could go wrong
This is an observational study, so it cannot prove cause and effect. Results may not apply to all patients or surgeries, and individual responses to nerve blocks vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 150 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Aug 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population comprises patients aged 50 years and older with an American Society of Anesthesiologists (ASA) physical status of I to III, who are scheduled to undergo upper extremity surgery under general anesthesia. Eligible participants must be capable of cooperating with postoperative pain and functional assessments.

Ages

50 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age\>=50 years old * ASA I-III * Receiving upper limb surgery under general anesthesia Exclusion Criteria: * Severe cognitive impairment or inability to cooperate with pain and motor assessment * Pre-existing neuropathy of the musculocutaneous, median, radial or ulnar nerve * (for nerve block group) Contraindications to regional nerve blockade

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Conditions

The condition(s) this trial relates to.

Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Nerve block Sarcopenia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • ChangGung Memorial Hospital

    Taoyuan, Taiwan

More trials for these conditions

Other studies related to the condition(s) this trial covers.