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Study seeks to unlock exercise secrets for seniors

NCT ID NCT06507189

Knowledge-focused Sponsor: Florida Institute for Human and Machine Cognition Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Aug 11, 2026 · Updated 5 times

Summary

This study looks at why older adults respond differently to the same exercise program. Researchers will have 250 healthy adults aged 60+ do a mix of cycling and strength training three times a week. The goal is to understand what makes exercise more effective for some, so future programs can be personalized.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
combined endurance and resistance training
What this could lead to
If successful, this could help tailor exercise programs to individual older adults, maximizing health benefits like fitness and balance.
What could go wrong
This is an observational study, not testing a new treatment. Results may not apply to all older adults, especially those with chronic diseases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 250 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2025

Expected to finish

Aug 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Male or female aged 60 or above 2. Free of chronic disease 3. No structured exercise program (2 or more bouts/wk) within previous 12 months 4. Cognitively capable of providing informed consent Exclusion Criteria: 1. Neuromuscular or musculoskeletal disorder that would limit ability to perform the exercise and/or testing bouts 2. Cardiopulmonary disorders or reduced breathing capacity 3. Metabolic diseases including markers of liver disease (ALT \> 52 U/l) and type 2 diabetes (HbA1C = or \> 6.5, fasting blood glucose = or \> 126 mg/dl) 4. Any other disease or disorder that would influence exercise response (e.g., chronic kidney disease, dementia, current cancer diagnosis or within 2 yr remission, cerebrovascular disease) 5. Any current infectious disease 6. Life expectancy \< 1 year 7. Insulin sensitizing/blood glucose lowering agents such as metformin or metabolic weight loss agents (e.g. GLP-1 agonists) 8. High dose statin (dose equivalent of 40 mg/d or higher simvastatin) 9. Lidocaine allergy 10. Regular tobacco use and/or vaping 11. Excessive alcohol consumption (3 drinks/d or 7 drinks/wk for females; 4 drinks/d or 14 drinks/wk for males) 12. BMI 35.0 kg/m2 or higher 13. Unable to commit to \~6 months required to complete the study

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Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aging Aging well Sarcopenia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Florida Institute for Human and Machine Cognition

    RECRUITING

    Pensacola, Florida, 32502, United States

  • Oklahoma Medical Research Foundation

    RECRUITING

    Oklahoma City, Oklahoma, 73104, United States

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