Safflower oil shows promise for fighting Age-Related muscle loss
NCT ID NCT06361511
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether eating a special oil (high in linoleic acid) every day can help older adults with muscle loss (sarcopenia) build stronger muscles and improve mobility. Researchers will give 66 participants either the oil or a placebo for a period, then measure changes in leg strength, muscle size, and fatigue. The goal is to find a simple dietary way to manage age-related muscle decline.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 66 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2025
- Expected to finish
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May 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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65 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Linoleic Acid Intake \<75% of the adequate intake * Probable sarcopenia Exclusion Criteria: * Gastrointestinal diseases or disorders (including pancreatic and gastric bypass surgery) where consumption of the study foods would be contraindication or where the disease or disorder could negatively affect nutrient absorption and/or would prevent participants from tolerating the study foods * Hyperthyroidism diagnosis * Food Allergy or intolerances * Any dietary restriction where consumption of the study foods or any ingredient would be contraindicated * Unstable management of heart failure, heart disease events (including stroke or heart attack) within last 3 months prior to enrollment, a plan for heart surgeries or cardiac procedures * Current or previous diagnosis of severe kidney failure, liver cirrhosis, other liver diseases/infections that cause liver damage and some pulmonary diseases or severe/uncontrolled pulmonary diseases * Severe or uncontrolled rheumatologic or orthopedic diseases * Current diagnosis of or current treatment of cancer other than non-melanoma skin cancer * Neuromuscular or neurological conditions or diseases or use of mobility assistance (wheelchair, walker etc..) that would impact movement needed to perform the muscle function tests or prevent completion of the muscle function tests * Use of mobility assistance (wheelchair, walker etc..) that would prevent completion of the muscle function tests * Current use of supplements or medications for weight loss or following a weight loss program * Use of supplements high in linoleic acid in the past 4 weeks prior to enrolling * Pregnancy and lactation * Alcohol or drug abuse * Allergy/intolerance to lidocaine or similar medication * Use of anticoagulant, antiplatelet, or other blood thinner medications * Terminal Illness * Any condition leading to muscle loss or weakness, impaired mobility or range of motion in legs (excluding normal aging)
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The places running it
1 site. The list below names each one and where it is.
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The official record
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A doctor treating you
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Contacts and locations
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Genom att skicka in godkänner du våra Användarvillkor
Study contacts
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Contact
Email: •••••@•••••
Locations
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The Ohio State University
RECRUITINGColumbus, Ohio, 43210, United States
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