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Vitamin d boost may speed Post-Surgery muscle recovery

NCT ID NCT06708741

Disease control Sponsor: Sengkang General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This phase 3 trial tests whether high-dose vitamin D (50,000 IU once a month) can improve muscle health in adults aged 21-65 who have low vitamin D levels after surgery. The study will measure vitamin D levels at 3, 6, and 12 months. If successful, it could point to a simple way to support recovery and quality of life after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Vitamin D (high-dose oral supplement, 50,000 IU once per month)
What this could lead to
If it works, this could show that high-dose vitamin D helps maintain muscle health and speed recovery after surgery.
What could go wrong
This is a small, early-phase trial with only 100 participants, so results may not apply to everyone. High-dose vitamin D can cause side effects like kidney stones or high calcium levels.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Serum 25-hydroxyvitamin D levels between 30-50ng/ml at 4-6 weeks after operation * aged 21-65 years * ability to provide informed consent * accepts to take vitamin D supplements post-operatively and * have their serum vitamin D levels checked periodically. Exclusion Criteria: * They have undergone minor procedures (Table code \<4a) * have a history of chronic kidney disease/end staged renal failure * have previous history of ureteric/kidney stones * known hyperparathyroidism * are non-ambulatory independently * have had known allergies to the commercially available high dose vitamin D formulations. * Vulnerable personnel would be excluded from the study

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Conditions

The condition(s) this trial relates to.

Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Sarcopenia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sengkang General Hospital

    RECRUITING

    Singapore, Singapore, 544886, Singapore

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