HEAD AND NECK CANCER
Clinical trials for HEAD AND NECK CANCER explained in plain language.
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New drug cocktail shows promise in fighting tough head and neck cancers
Disease control Recruiting nowThis study tests a new immunotherapy drug (iparomlimab and tuvonralimab) combined with radiation and chemotherapy for people with advanced head and neck cancer that hasn't spread. The goal is to see if this combination can keep the cancer from coming back for at least one year. A…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Disease control
Last updated May 26, 2026 03:21 UTC
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Blood test may guide smarter chemo for head and neck cancer
Disease control Recruiting nowThis study tests whether a blood test that tracks tumor DNA can help doctors decide when to add short bursts of chemotherapy to standard immunotherapy for people with recurrent or metastatic head and neck cancer. About 30 adults will receive pembrolizumab (immunotherapy) plus occ…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: University of Chicago • Aim: Disease control
Last updated May 26, 2026 03:21 UTC
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New drug duo shows promise against tough head and neck cancer
Disease control Recruiting nowThis study tests a combination of the experimental drug volrustomig with standard chemotherapy (paclitaxel and carboplatin) in people with untreated, locally advanced HPV-negative head and neck cancer. After initial treatment, the next steps are tailored based on how well the tum…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: University of Chicago • Aim: Disease control
Last updated May 26, 2026 03:20 UTC
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New drug targets rare cancer mutation in 300-Patient trial
Disease control Recruiting nowThis study tests a new drug called PC14586 (rezatapopt) in people with advanced solid tumors that have a specific TP53 Y220C mutation. The goal is to see if the drug is safe and shrinks tumors. About 300 adults whose cancer has worsened after prior treatment will take the drug al…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE1, PHASE2 • Sponsor: PMV Pharmaceuticals, Inc • Aim: Disease control
Last updated May 26, 2026 03:20 UTC
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New drug ALX2004 targets Hard-to-Treat cancers in first human trial
Disease control Recruiting nowThis early-phase study tests a new drug called ALX2004 in people with advanced lung, head and neck, colorectal, or esophageal cancers that have stopped responding to standard treatments. ALX2004 is an antibody-drug conjugate designed to deliver a toxic payload directly to cancer …
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE1 • Sponsor: ALX Oncology Inc. • Aim: Disease control
Last updated May 26, 2026 03:19 UTC
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Promising new combo therapy for recurrent head and neck cancer shows hope
Disease control Recruiting nowThis study is for people whose head and neck cancer has come back after previous radiation. It tests whether giving a type of immunotherapy (pembrolizumab) along with either standard or proton radiation before surgery is safe and works better than surgery alone. About 40 adults w…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE1, PHASE2 • Sponsor: University of Cincinnati • Aim: Disease control
Last updated May 26, 2026 03:16 UTC
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Could less radiation be enough for head and neck cancer?
Disease control Recruiting nowThis study is testing a new approach for people with certain head and neck cancers: using lower doses of radiation and chemotherapy, followed by surgery to remove any remaining cancer in the neck. The goal is to see if this gentler treatment can still control the cancer while red…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 26, 2026 03:16 UTC
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Antibiotics aim to shrink hidden bacteria in oral tumors
Disease control Recruiting nowThis study tests whether a short course of antibiotics (metronidazole) and mouthwash (chlorhexidine) can lower the amount of bacteria living inside oral cancer tumors. About 30 adults scheduled for oral cancer surgery will receive the treatment before their operation. Researchers…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: Case Comprehensive Cancer Center • Aim: Disease control
Last updated May 26, 2026 03:16 UTC
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DNA-Guided cancer drug trial aims to match treatment to tumor
Disease control Recruiting nowThis study tests a drug called atezolizumab in about 200 adults with advanced solid tumors (like breast, lung, or colon cancer) whose tumor DNA suggests the drug might help. Participants get the same dose every 3 weeks, and researchers check if their cancer shrinks or stops growi…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: British Columbia Cancer Agency • Aim: Disease control
Last updated May 26, 2026 03:14 UTC
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New hope for recurrent head and neck cancer: drug combo trial launches
Disease control Recruiting nowThis study tests a new combination of drugs and radiation for people whose head and neck cancer has returned after previous treatment. The goal is to find the safest dose and see how well the treatment works. About 30 participants will receive the drugs tislelizumab and pamiparib…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE1 • Sponsor: University of Chicago • Aim: Disease control
Last updated May 26, 2026 03:14 UTC
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Could less radiation be better for head and neck cancer?
Disease control Recruiting nowThis study is for people with head and neck cancer. It compares two types of radiation therapy: one that treats only the cancer and nearby lymph nodes (INRT) and one that treats a larger area (ENI). The goal is to see if the smaller treatment area works just as well and causes fe…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: University of Texas Southwestern Medical Center • Aim: Disease control
Last updated May 26, 2026 03:14 UTC
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New antibody drug shows promise for tough cancers
Disease control Recruiting nowThis study tests an experimental drug called MCLA-129 in people with advanced solid tumors, including lung, head and neck, and colorectal cancers that have stopped responding to standard treatments. The drug is a bispecific antibody designed to target two cancer-related proteins …
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE1, PHASE2 • Sponsor: Betta Pharmaceuticals Co., Ltd. • Aim: Disease control
Last updated May 26, 2026 03:14 UTC
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New drug combo may let some head and neck cancer patients skip radiation after surgery
Disease control Recruiting nowThis study tests whether adding two immunotherapy drugs (cemiplimab and cetuximab) to standard chemotherapy before surgery is safe and effective for people with advanced head and neck cancer. The goal is to see if this combination can help patients avoid needing radiation therapy…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 26, 2026 03:14 UTC
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Proton beam offers new hope for patients with recurrent tumors
Disease control Recruiting nowThis study looks at whether proton therapy can safely treat tumors that have returned after previous radiation. Unlike standard X-ray radiation, proton beams are more targeted and may spare healthy tissue. The trial will enroll 1,800 adults with various cancers to see if this app…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: The New York Proton Center • Aim: Disease control
Last updated May 26, 2026 03:13 UTC
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Pill combo could offer new hope for rural head and neck cancer patients
Disease control Recruiting nowThis study is testing whether taking three oral drugs (methotrexate, erlotinib, and celecoxib) together is safe and practical for people with head and neck cancer that has come back or spread. The trial focuses on patients in rural Midwest areas, aiming to make treatment more acc…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 26, 2026 03:13 UTC
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Engineered immune cells take on Hard-to-Treat head and neck cancer
Disease control Recruiting nowThis early-phase study tests a new treatment for advanced head and neck cancer that has stopped responding to standard therapies. The treatment uses specially engineered natural killer (NK) cells from donated cord blood, designed to better target cancer cells and resist tumor def…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 03:12 UTC
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Oral cancer patients may avoid unnecessary neck radiation
Disease control Recruiting nowThis study tests whether it is safe to skip radiation to the lymph nodes in the neck after surgery for early-stage oral cancer. About 396 adults aged 18-70 with certain high-risk features will be randomly assigned to receive or skip this radiation. The goal is to see if skipping …
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2, PHASE3 • Sponsor: All India Institute of Medical Sciences • Aim: Disease control
Last updated May 26, 2026 03:12 UTC
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New combo aims to shrink head and neck tumors, sparing patients from radical surgery
Disease control Recruiting nowThis study tests giving chemotherapy and immunotherapy before standard surgery for head and neck cancer. The goal is to shrink tumors enough so that surgeons can do a less extensive operation, preserving speech, swallowing, and vision. About 75 adults with newly diagnosed, advanc…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Disease control
Last updated May 26, 2026 03:11 UTC
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New treatment schedule may help patients complete more chemo cycles
Disease control Recruiting nowThis study is for people with advanced lung or head & neck cancers. It tests a new way of giving chemotherapy and immunotherapy (pembrolizumab) by alternating cycles. The goal is to see if this schedule helps patients complete more treatment cycles and improves cancer control. Ab…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated May 26, 2026 03:11 UTC
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Can Six-Day radiation beat Five-Day for head and neck cancer?
Disease control Recruiting nowThis study looks at whether giving radiation therapy six days a week (instead of the usual five) can better control head and neck cancer in people who start treatment more than six weeks after surgery. About 75 adults with certain types of head and neck cancer will be randomly as…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated May 26, 2026 03:10 UTC
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Could less radiation be just as effective for HPV throat cancer?
Disease control Recruiting nowThis study is for people with HPV-related throat cancer who have had surgery. It tests whether a lower, personalized dose of radiation (and sometimes chemo) can control the cancer while causing fewer side effects and improving quality of life. About 111 adults will take part, and…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated May 26, 2026 03:10 UTC
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New drug MDX2001 tested in 285 patients with advanced cancers
Disease control Recruiting nowThis early-phase trial tests a new drug called MDX2001 in about 285 adults with advanced solid tumors (cancers that have spread). The main goals are to check the drug's safety and find the right dose. Researchers will also see if it shrinks tumors. This is not a cure, but it may …
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE1, PHASE2 • Sponsor: ModeX Therapeutics, An OPKO Health Company • Aim: Disease control
Last updated May 26, 2026 03:04 UTC
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New program aims to speed up cancer treatment after surgery
Disease control Recruiting nowThis study tests a program called ENDURE that helps head and neck cancer patients start radiation therapy within 6 weeks after surgery, as guidelines recommend. About 532 adults with certain types of head and neck cancer will take part. The program uses patient navigators to guid…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated May 26, 2026 03:04 UTC
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Sound waves may boost immunotherapy in head and neck cancer
Disease control Recruiting nowThis early-stage trial tests whether using ultrasound and microbubbles can help deliver the immunotherapy drug pembrolizumab more effectively to tumors in people with recurrent or metastatic head and neck cancer. Six participants will receive three rounds of treatment. The main g…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE1 • Sponsor: Thomas Jefferson University • Aim: Disease control
Last updated May 26, 2026 03:03 UTC
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New hope for Hard-to-Treat HER2 cancers: T-DXd under Real-World study
Disease control Recruiting nowThis study looks at how well the drug T-DXd works for people with advanced HER2-positive solid tumors who have already tried other treatments and have no good options left. About 100 adults in the US will be followed to see if their tumors shrink or stop growing. The goal is to u…
Matched conditions: HEAD AND NECK CANCER
Sponsor: AstraZeneca • Aim: Disease control
Last updated May 26, 2026 02:49 UTC
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New smart drug targets tough cancers in early trial
Disease control Recruiting nowThis early-phase study tests an experimental drug called PF-08046876 in adults with advanced solid tumors (bladder, lung, head/neck, esophagus, or pancreatic cancer) that have not responded to standard treatments. The drug is an antibody-drug conjugate designed to stick to cancer…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE1 • Sponsor: Pfizer • Aim: Disease control
Last updated May 22, 2026 13:54 UTC
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New cancer drug OCT-598 enters first human tests for advanced tumors
Disease control Recruiting nowThis early-stage study tests a new drug called OCT-598 in about 51 adults with advanced solid tumors (breast, lung, prostate, head/neck, or stomach cancer). The main goals are to check safety, find the best dose, and see how the drug works alone or with standard treatments. Parti…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE1 • Sponsor: Oscotec Inc. • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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New hope for head & neck cancer: Triple-Drug combo tested after immunotherapy fails
Disease control Recruiting nowThis study tests a combination of three drugs (carboplatin, paclitaxel, and cetuximab) in adults with head and neck cancer that has spread or returned and did not respond to first-line immunotherapy. The goal is to see if this second-line treatment can shrink tumors and control t…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: Centre Paul Strauss • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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New drug EPI-326 enters first human tests for tough cancers
Disease control Recruiting nowThis early-phase study tests a new drug called EPI-326 in about 110 people with advanced lung cancer (with a specific EGFR gene change) or head/neck cancer. The main goal is to check safety and find the best dose. Participants receive the drug and are monitored for side effects a…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE1 • Sponsor: EpiBiologics • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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Triple therapy aims to reignite immune attack on hard-to-treat head and neck cancer
Disease control Recruiting nowThis study tests whether combining three treatments—modified natural killer cells (PD-L1 t-haNK), an immune-boosting protein (Anktiva), and a targeted antibody (cetuximab)—can shrink tumors in people with advanced head and neck cancer that has come back or spread. About 25 adults…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: Glenn J. Hanna • Aim: Disease control
Last updated May 22, 2026 13:50 UTC
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Targeted radiation zaps Hard-to-Treat cancers in early trial
Disease control Recruiting nowThis early-stage study tests a new drug that delivers radiation directly to cancer cells. It is for people with advanced solid tumors like bladder, breast, lung, or cervical cancer that have not responded to prior treatments. The main goals are to find the safest dose and see if …
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE1 • Sponsor: Aktis Oncology, Inc. • Aim: Disease control
Last updated May 20, 2026 11:56 UTC
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Engineered immune cells take on returning head and neck cancer
Disease control Recruiting nowThis study is for people with head and neck cancer that has returned after standard treatments. It tests a new therapy where a patient's own immune cells are modified in a lab to better recognize and attack cancer cells. The main goals are to see if the treatment is safe and to f…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE1, PHASE2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated May 19, 2026 12:00 UTC
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New injection combo shows promise against head and neck cancer
Disease control Recruiting nowThis early-phase study tests a new drug, VLPONC-01, injected directly into head and neck tumors to see if it's safe and can shrink tumors. About 41 adults with advanced head and neck cancer will receive the injection alone or with an immunotherapy drug (pembrolizumab). The goal i…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE1 • Sponsor: VLP Therapeutics • Aim: Disease control
Last updated May 18, 2026 12:10 UTC
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New drug targets hard-to-treat cancers in massive trial
Disease control Recruiting nowThis study tests an experimental drug called patritumab deruxtecan in people with advanced solid tumors that have spread or cannot be removed. The drug targets a protein called HER3 found on some cancer cells. About 740 adults with various cancers like lung, breast, or melanoma w…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: Daiichi Sankyo • Aim: Disease control
Last updated May 18, 2026 12:04 UTC
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Smart radiation: MRI-Guided boost aims to cut side effects in head and neck cancer
Disease control Recruiting nowThis study tests whether MRI scans can help doctors adjust radiation therapy for head and neck cancer patients to better target tumors while sparing healthy tissues. About 35 adults with squamous cell carcinoma will receive a personalized radiation boost based on MRI response. Th…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated May 18, 2026 12:01 UTC
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New Alpha-Particle therapy targets Hard-to-Treat cancers
Disease control Recruiting nowThis study is testing a new treatment that uses a radioactive substance to target and destroy cancer cells in people with advanced solid tumors (like pancreatic, stomach, or ovarian cancer) that have not responded to standard treatments. The therapy works by attaching to a protei…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE1, PHASE2 • Sponsor: Perspective Therapeutics • Aim: Disease control
Last updated May 18, 2026 12:01 UTC
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Last-Resort drug made available for patients with tough cancers
Disease control AVAILABLEThis program provides ulixertinib, an experimental drug, to adults with advanced solid tumors that have specific genetic changes (MAPK pathway mutations) and who have run out of standard treatments. The goal is to control the cancer, not cure it. Participants may take ulixertinib…
Matched conditions: HEAD AND NECK CANCER
Sponsor: xCures • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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New immune therapy aims to keep head and neck cancer at bay
Disease control Recruiting nowThis study tests whether ongoing immune therapy can help prevent head and neck cancer from coming back in patients who already had a strong response to initial treatment. About 268 adults aged 18 to 80 with locally advanced head and neck cancer will receive immune maintenance the…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: Tianjin Medical University Cancer Institute and Hospital • Aim: Disease control
Last updated May 13, 2026 16:01 UTC
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New MRI scan could predict jaw bone damage in cancer patients
Diagnosis Recruiting nowThis study is testing whether a special type of MRI (DCE-MRI) can predict a serious side effect called osteoradionecrosis (jaw bone damage) in people with head and neck cancer who are receiving radiation therapy. Researchers will scan 1,400 participants before, during, and after …
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Diagnosis
Last updated May 26, 2026 03:18 UTC
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New PET scan could spot cancers more accurately
Diagnosis Recruiting nowThis study is testing a new type of PET scan that targets a protein called Trop2, found on many solid tumors. The goal is to see if this scan can find and stage cancers like bladder, lung, liver, and ovarian cancer better than current methods. About 400 adults with confirmed or s…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2, PHASE3 • Sponsor: RenJi Hospital • Aim: Diagnosis
Last updated May 26, 2026 03:15 UTC
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Glow-in-the-Dark dye could help surgeons find hidden cancers
Diagnosis Recruiting nowThis study tests a special dye called pegsitacianine that makes cancer cells glow during surgery. The goal is to help surgeons see and remove all cancer tissue in people with head and neck cancer, especially when the original tumor location is unknown. About 120 adults will recei…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: University of Texas Southwestern Medical Center • Aim: Diagnosis
Last updated May 26, 2026 03:13 UTC
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Glow-in-the-Dark dye could help surgeons spot hidden cancer
Diagnosis Recruiting nowThis study tests whether a dye called panitumumab-IRDye800 can make head and neck cancer cells glow during surgery, helping surgeons see and remove them more accurately. About 25 adults with head and neck cancer who are already scheduled for surgery will receive the dye beforehan…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: University of Alabama at Birmingham • Aim: Diagnosis
Last updated May 26, 2026 03:11 UTC
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New blood test aims to catch 20 cancers before symptoms start
Diagnosis Recruiting nowThis study is testing a blood test that looks for DNA signals from 20 different cancers, including lung, breast, and colon cancer. Researchers will see if the test can find cancer early and tell which type it is. In people with lung cancer, the test will also check for any cancer…
Matched conditions: HEAD AND NECK CANCER
Sponsor: Adela, Inc • Aim: Diagnosis
Last updated May 18, 2026 12:03 UTC
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New imaging agent could sharpen cancer detection
Diagnosis Recruiting nowThis study is testing a new type of PET/CT scan that uses a special tracer called 18F-T2 to find cancers that have high levels of a protein called CAIX. About 200 adults with cancers like kidney, bladder, lung, or breast cancer will get this scan to see if it works better than th…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Peking University First Hospital • Aim: Diagnosis
Last updated May 18, 2026 12:00 UTC
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Glow-in-the-dark dye helps surgeons see hidden cancer during head and neck operations
Diagnosis Recruiting nowThis study tests whether a near-infrared camera and a dye called indocyanine green can help surgeons spot tiny bits of cancer left behind during head and neck cancer surgery. About 65 adults with mouth or throat cancer will receive the dye before surgery, and the camera will scan…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: Gustave Roussy, Cancer Campus, Grand Paris • Aim: Diagnosis
Last updated May 13, 2026 16:03 UTC
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New laser camera could spot mouth cancer without a knife
Diagnosis Recruiting nowThis study is testing a special camera that uses a laser to take detailed pictures of mouth sores before surgery. The goal is to see if these pictures can help doctors find oral cancer cells without needing a biopsy. About 140 people with mouth cancer will have their sores photog…
Matched conditions: HEAD AND NECK CANCER
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Diagnosis
Last updated May 07, 2026 18:41 UTC
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Pill vs. shot: which is better for preventing clots after cancer surgery?
Prevention Recruiting nowThis study tests whether a pill (apixaban) is a safe and more convenient alternative to a daily shot (enoxaparin) for preventing blood clots after head and neck cancer surgery. About 76 adults will take one of the two medicines for 10 days after surgery and complete surveys about…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE4 • Sponsor: Kiranya Arnold • Aim: Prevention
Last updated May 22, 2026 13:52 UTC
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Nerve transfer offers new hope for facial paralysis in cancer patients
Symptom relief Recruiting nowThis study looks at whether nerve transfer surgery can improve facial movement and quality of life for cancer patients who have facial paralysis after treatment. About 40 adults who are scheduled for this surgery will take part. Researchers will track side effects and measure cha…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated May 26, 2026 03:21 UTC
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Light therapy offers hope for cancer survivors with persistent swelling
Symptom relief Recruiting nowThis study tests a light-based treatment (photobiomodulation) to reduce chronic swelling in the head and neck area in people who have finished cancer treatment. About 150 survivors will receive either real or placebo light therapy to see if it eases their lymphedema. The goal is …
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Symptom relief
Last updated May 26, 2026 03:21 UTC
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Hearing shield: new drug may protect ears during cancer treatment
Symptom relief Recruiting nowThis study tests if a drug called Pedmark (sodium thiosulfate) can reduce hearing loss in adults receiving cisplatin chemotherapy for cancers like testicular, head and neck, or thoracic cancer. About 25 participants will receive Pedmark alongside their standard chemo. The goal is…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE1, PHASE2 • Sponsor: University of Arizona • Aim: Symptom relief
Last updated May 26, 2026 03:19 UTC
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Jaw-Saving therapy tested for cancer patients
Symptom relief Recruiting nowThis study looks at whether closely watching jaw movement and starting physical therapy early can help prevent or reduce jaw tightness (trismus) in people with head and neck cancer who are getting radiation. About 30 participants will be tracked weekly during treatment and given …
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated May 26, 2026 03:17 UTC
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New diet plan aims to stop weight loss after cancer surgery
Symptom relief Recruiting nowThis study tests whether extra nutrition support before and after surgery helps head and neck cancer patients maintain their weight. 60 adults having surgery will either get standard care or enhanced care with diet advice, follow-up calls, and monthly check-ins for 6 months. The …
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated May 26, 2026 03:17 UTC
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Tongue workout after cancer surgery may boost speech and swallowing
Symptom relief Recruiting nowThis study tests whether starting a tongue strengthening exercise program soon after tongue cancer surgery can improve speech and swallowing. About 40 adults who have part of their tongue removed will use a biofeedback device called the Tongueometer to do the exercises. The goal …
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Case Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 26, 2026 03:16 UTC
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Heavy lifting may boost recovery for head and neck cancer survivors
Symptom relief Recruiting nowThis study tests whether a heavy lifting strength training program can help head and neck cancer survivors regain muscle strength, reduce fatigue, and improve quality of life. About 60 adults who finished cancer treatment at least one year ago will be randomly assigned to either …
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: University of Alberta • Aim: Symptom relief
Last updated May 26, 2026 03:15 UTC
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Prehabilitation program aims to boost strength and mood in head and neck cancer patients
Symptom relief Recruiting nowThis study tests whether a personalized program of exercise, nutrition advice, and counseling—started about 4 weeks before cancer treatment and continued through therapy—can help head and neck cancer patients maintain physical function, reduce malnutrition risk, and improve quali…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Laura Deborah Locati • Aim: Symptom relief
Last updated May 26, 2026 03:14 UTC
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Virtual yoga and meditation may ease cancer fatigue, new study hopes to prove
Symptom relief Recruiting nowThis study tests whether a virtual mind-body program called IM@Home can reduce fatigue and improve quality of life for adults with head and neck, thoracic, gynecologic, or other cancers who are receiving treatments like chemotherapy or radiation. About 480 participants will be en…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Symptom relief
Last updated May 26, 2026 03:13 UTC
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Light therapy may soothe radiation damage in head and neck cancer patients
Symptom relief Recruiting nowThis study tests whether a special light treatment (photobiomodulation) can reduce swelling and tissue hardening caused by radiation therapy in head and neck cancer survivors. About 60 participants who completed radiation at least 3 months ago will receive either the light treatm…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: NYU Langone Health • Aim: Symptom relief
Last updated May 26, 2026 03:12 UTC
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Video games could ease cancer fatigue: new study tests nintendo switch for head & neck survivors
Symptom relief Recruiting nowThis study tests whether a personalized exercise program using motion-controlled video games (like Nintendo Switch) can help head and neck cancer survivors reduce fatigue and pain after treatment. 150 participants who have finished radiation or chemotherapy will be assigned to ei…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated May 26, 2026 03:11 UTC
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New gel may ease radiation mouth pain for cancer patients
Symptom relief Recruiting nowThis study tests a special gel and mouthwash (XCM-OM118) in 63 head and neck cancer patients getting radiation, with or without chemo. The goal is to see if it lowers the chance of severe mouth sores and improves quality of life. Patients use the product during radiation and late…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Mucosa Innovations, S.L. • Aim: Symptom relief
Last updated May 26, 2026 03:09 UTC
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Diet and workout program aims to ease chemo side effects for cancer patients
Symptom relief Recruiting nowThis study tests whether a program of nutrition counseling, guided exercise, and wellness education can help head and neck cancer patients undergoing chemoradiation feel better and stay stronger. Researchers will enroll 30 adults to see if the program is practical and helpful dur…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Renown Health • Aim: Symptom relief
Last updated May 26, 2026 03:06 UTC
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Can a psoriasis drug tame Immunotherapy's harsh side effects?
Symptom relief Recruiting nowThis pilot study tests if brodalumab, a drug approved for autoimmune diseases, can safely reduce severe side effects caused by cancer immunotherapy. About 11 adults with various solid tumors who have immune-related side effects will receive brodalumab. The goal is to see if it lo…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE1 • Sponsor: Brian Henick, MD • Aim: Symptom relief
Last updated May 26, 2026 03:03 UTC
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Shock relief: electrical therapy may ease dry mouth for cancer survivors
Symptom relief Recruiting nowThis study looks at whether a non-invasive, acupuncture-like electrical treatment (ALTENS) can reduce dry mouth in people who had radiation for head and neck cancer. About 75 adults who completed radiation at least 3 months ago and still have dry mouth will receive weekly session…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: University of Rochester • Aim: Symptom relief
Last updated May 22, 2026 13:54 UTC
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New radiation technique aims to cut severe mouth sores in head and neck cancer
Symptom relief Recruiting nowThis study compares standard radiation therapy to a new 'dose-painting' method for people with head and neck cancer. The new approach gives higher radiation doses to the most active parts of the tumor while aiming to reduce severe side effects like mouth ulcers. About 100 partici…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Oslo University Hospital • Aim: Symptom relief
Last updated May 22, 2026 13:52 UTC
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Light therapy offers hope for cancer survivors battling chronic dry mouth
Symptom relief Recruiting nowThis study tests whether a special light therapy (photobiomodulation) can improve dry mouth, swallowing, and overall quality of life in 60 head and neck cancer survivors who have completed radiation. Participants use a mobile health tool to track symptoms. The goal is to ease lon…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Universidad de Granada • Aim: Symptom relief
Last updated May 22, 2026 13:51 UTC
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Common statin may shield ears from chemo damage
Symptom relief Recruiting nowThis study tests if atorvastatin, a common cholesterol drug, can reduce hearing loss caused by cisplatin chemotherapy in people with head and neck cancer. About 224 adults will either take atorvastatin or a placebo daily during and for 3 months after chemo. Hearing tests and bloo…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: National Institute on Deafness and Other Communication Disorders (NIDCD) • Aim: Symptom relief
Last updated May 22, 2026 13:50 UTC
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Spa treatment may ease radiation skin damage in cancer survivors
Symptom relief Recruiting nowThis study tests whether a special spa therapy can improve skin-related quality of life in people who have skin hardening (fibrosis) after radiation for breast or head/neck cancer. About 110 adults who finished radiation at least 6 months ago will be randomly assigned to get spa …
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Association Francaise pour la Recherche Thermale • Aim: Symptom relief
Last updated May 20, 2026 11:57 UTC
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Moving more, sitting less: new study aims to boost health in head and neck cancer patients
Symptom relief Recruiting nowThis study tests whether a structured physical activity program can help people with upper aerodigestive tract (head and neck) cancer reduce their sedentary time and increase physical activity over 18 months. About 96 adults with newly diagnosed, non-spreading cancer will be rand…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Centre Hospitalier de Valence • Aim: Symptom relief
Last updated May 20, 2026 11:56 UTC
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New study aims to shrink radiation zones, spare healthy tissue in head and neck cancer
Symptom relief Recruiting nowThis study tests whether giving radiation only to high-risk areas after head and neck cancer surgery can reduce side effects without raising the chance of cancer coming back. About 50 adults with certain head and neck cancers will receive a personalized radiation plan. The goal i…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: Olgun Elicin • Aim: Symptom relief
Last updated May 20, 2026 11:55 UTC
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New skin flap aims to reduce side effects after head and neck cancer surgery
Symptom relief Recruiting nowThis study tests a new surgical technique using a skin flap from the groin area to rebuild the mouth or throat after cancer removal. The goal is to see if this method causes fewer complications at the donor site compared to standard flaps. About 40 adults with head and neck cance…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Institut Claudius Regaud • Aim: Symptom relief
Last updated May 20, 2026 11:54 UTC
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Miracle fruit may restore taste for cancer patients
Symptom relief Recruiting nowThis study tests whether a special fruit cube (miracle fruit) can improve taste problems in people with head and neck cancer who are getting radiation therapy. About 40 participants will receive either the fruit cube or a placebo to see if it helps them taste food better and eat …
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE3 • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated May 20, 2026 11:54 UTC
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New hope for chemo brain: drug may shield memory during cancer treatment
Symptom relief Recruiting nowThis study tests whether the drug riluzole can prevent memory and thinking problems (often called 'chemo brain') in people receiving chemotherapy for various cancers. About 24 adults with breast, lung, or other cancers will receive either riluzole or a placebo during their chemo.…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: University of California, Irvine • Aim: Symptom relief
Last updated May 18, 2026 12:13 UTC
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New MRI technique aims to prevent dry mouth after cancer radiation
Symptom relief Recruiting nowThis study tests a new way to give radiation for head and neck cancer that may reduce dry mouth, a common and severe side effect. About 98 adults with oropharynx cancer will be randomly assigned to standard radiation or a technique guided by MRI that spares the saliva ducts. The …
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 18, 2026 12:11 UTC
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Nurse-Led care may keep head and neck cancer patients on track during radiation
Symptom relief Recruiting nowThis study tests a nurse-led program that helps head and neck cancer patients manage symptoms early during radiation therapy. The goal is to see if this approach reduces treatment interruptions compared to standard care. About 170 adults with head and neck cancer will take part. …
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE3 • Sponsor: West China Hospital • Aim: Symptom relief
Last updated May 18, 2026 12:02 UTC
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AI nurse chatbot aims to ease cancer Patients' radiotherapy stress
Symptom relief Recruiting nowThis study tests a chatbot called Digi-Coach to see if it can lower physical and emotional distress in people receiving radiation for head and neck cancer. About 138 adults will either use the chatbot plus standard care or just standard care. The chatbot lets patients ask questio…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: The University of Hong Kong • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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New video therapy aims to ease body image struggles after head and neck cancer
Symptom relief Recruiting nowThis study tests a short video-based therapy called BRIGHT to help head and neck cancer survivors who feel distressed about changes in their appearance. About 180 survivors will be randomly assigned to BRIGHT or a supportive talk session. The goal is to see if BRIGHT reduces body…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated May 15, 2026 11:55 UTC
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Can caregiver training ease the burden after head and neck cancer surgery?
Symptom relief Recruiting nowThis study looks at whether special training for caregivers of head and neck cancer patients can make a difference. After surgery, patients often have trouble breathing, eating, and speaking. The training teaches caregivers how to help with these needs so the patient can safely r…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Symptom relief
Last updated May 13, 2026 16:04 UTC
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Chill out: cooling device may save your taste buds during cancer radiation
Symptom relief Recruiting nowThis study tests a special cooling mouthpiece used during radiation therapy for larynx cancer. The goal is to see if cooling the mouth can prevent or reduce taste loss, a common side effect of radiation. About 15 adults with advanced larynx cancer will try the device and report c…
Matched conditions: HEAD AND NECK CANCER
Phase: EARLY_PHASE1 • Sponsor: Henry Ford Health System • Aim: Symptom relief
Last updated May 13, 2026 15:58 UTC
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New study offers simple fluoride treatment to protect teeth after cancer radiation
Symptom relief Recruiting nowThis study looks at whether giving fluoride varnish during regular cancer follow-up visits can help improve oral health for head and neck cancer patients who have had radiation and lack easy access to dental care. About 120 uninsured or underinsured adults will take part. Researc…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated May 12, 2026 13:49 UTC
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Blood clues may foretell chemo nerve pain
Knowledge-focused Recruiting nowThis study aims to find out if tiny particles in the blood, called extracellular vesicles, can predict nerve damage caused by chemotherapy. About 120 adults with certain cancers will give blood samples and answer questionnaires before, during, and after treatment. The goal is to …
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico • Aim: Knowledge-focused
Last updated May 26, 2026 03:21 UTC
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Scientists launch massive study to spy on immune cells in tumors
Knowledge-focused Recruiting nowThis study looks at immune cells (T cells) in tumor samples from 1,100 people with cancers like head and neck, ovarian, cervical, lung, and brain cancer. Researchers want to understand how these cells behave, especially a protein called PD-1. No new treatments are tested—only sam…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Institut Claudius Regaud • Aim: Knowledge-focused
Last updated May 26, 2026 03:20 UTC
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Pre-Surgery fitness program tested for head and neck cancer patients
Knowledge-focused Recruiting nowThis study looks at whether a 2-week exercise and nutrition program before head and neck cancer surgery is safe and doable. About 20 adults with a new head and neck cancer diagnosis will take part. The goal is to see if patients can complete the program and if they find it accept…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated May 26, 2026 03:20 UTC
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Rural cancer care boost: new study tests support program
Knowledge-focused Recruiting nowThis study is testing a program called CARES that provides advocacy, resources, education, and support to rural cancer patients. The goal is to see if it helps them start treatment sooner and finish it on time. About 320 adults with solid tumors like lung, breast, or colon cancer…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated May 26, 2026 03:20 UTC
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Bacteria in your mouth could help fight cancer: new study explores link
Knowledge-focused Recruiting nowThis study looks at how the natural bacteria in your mouth might affect how well radiation therapy works for head and neck cancer. Researchers will collect saliva samples from 100 patients before, during, and after treatment to see if certain bacteria help control tumors or reduc…
Matched conditions: HEAD AND NECK CANCER
Sponsor: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano • Aim: Knowledge-focused
Last updated May 26, 2026 03:20 UTC
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Can nutrition and exercise before cancer treatment improve outcomes? new study seeks answers
Knowledge-focused Recruiting nowThis study looks at how to help head and neck cancer patients get nutritional counseling and exercise programs before and during radiation therapy. Researchers want to understand what helps or prevents patients from using these services. The goal is to make prehabilitation progra…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: University of Miami • Aim: Knowledge-focused
Last updated May 26, 2026 03:19 UTC
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Can a simple throat injection restore speech and swallowing for cancer survivors?
Knowledge-focused Recruiting nowSome head and neck cancer survivors develop a condition called velopharyngeal dysfunction (VPD), where the soft palate doesn't close properly, causing nasal-sounding speech and trouble swallowing. This study with 20 adults will first measure how common and severe VPD is, then tes…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Vanessa Torrecillas • Aim: Knowledge-focused
Last updated May 26, 2026 03:19 UTC
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Lab-Grown tumor clones could personalize head and neck cancer care
Knowledge-focused Recruiting nowThis study takes tumor samples from 120 people with head and neck cancer and grows them in the lab as mini tumors called organoids. Researchers will test different treatments on these organoids to see which ones work best, with the goal of choosing the most effective therapy for …
Matched conditions: HEAD AND NECK CANCER
Sponsor: Centre Francois Baclesse • Aim: Knowledge-focused
Last updated May 26, 2026 03:18 UTC
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Simple blood test could spot cancer return sooner
Knowledge-focused Recruiting nowThis study is testing whether a blood test that looks for tiny bits of tumor DNA (ctDNA) can find cancer early after treatment. Researchers will follow about 100 people with different solid tumors, plus healthy volunteers, to see if the test helps predict when cancer comes back. …
Matched conditions: HEAD AND NECK CANCER
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated May 26, 2026 03:16 UTC
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New scanner could help surgeons see cancer details right after removal
Knowledge-focused Recruiting nowThis study is testing a special PET-CT scanner that takes detailed pictures of cancer tissue right after it is removed during surgery. Researchers want to see if these images match the standard lab analysis and if they help doctors make better decisions. About 850 people with pro…
Matched conditions: HEAD AND NECK CANCER
Sponsor: XEOS Medical • Aim: Knowledge-focused
Last updated May 26, 2026 03:16 UTC
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New study aims to unlock secrets of head and neck cancer in korean patients
Knowledge-focused Recruiting nowThis study is collecting medical information and tissue samples from 350 adults with head and neck cancer at Samsung Medical Center. Researchers want to understand why some patients respond better to treatment than others. The goal is to find biological markers that can help doct…
Matched conditions: HEAD AND NECK CANCER
Sponsor: Samsung Medical Center • Aim: Knowledge-focused
Last updated May 26, 2026 03:16 UTC
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Blood test may spare oral cancer patients unnecessary chemo
Knowledge-focused Recruiting nowThis study looks at whether a simple blood test that finds leftover cancer cells (circulating tumor cells) can help doctors decide if oral cancer patients need extra chemotherapy after their usual treatment. About 100 people who have finished surgery and chemoradiation for oral c…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Chang Gung Memorial Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 03:15 UTC
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New study tracks survival after second surgery for head and neck cancer
Knowledge-focused Recruiting nowThis study looks at how well people do after a second surgery (salvage surgery) for head and neck cancer that has come back or remained after initial treatment. Researchers will track survival and quality of life in 400 adults. They will also study tumor genetics to understand wh…
Matched conditions: HEAD AND NECK CANCER
Sponsor: Royal Marsden NHS Foundation Trust • Aim: Knowledge-focused
Last updated May 26, 2026 03:14 UTC
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Live tumor biopsies could unlock secrets of immunotherapy success
Knowledge-focused Recruiting nowThis study collects tumor samples from 2,000 people with various cancers to learn how to predict who will respond to immunotherapy. Participants donate tissue during a routine biopsy. The goal is to understand tumor biology and improve future treatment decisions, not to test a ne…
Matched conditions: HEAD AND NECK CANCER
Sponsor: Elephas • Aim: Knowledge-focused
Last updated May 26, 2026 03:14 UTC
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Thousands of cancer patients needed for groundbreaking sample collection study
Knowledge-focused Recruiting nowThis study collects blood and leftover tissue samples from 9,600 adults with different types of cancer. Researchers will use these samples to develop and improve tests that detect cancer DNA in the blood, which may help monitor for cancer return or how well treatment is working. …
Matched conditions: HEAD AND NECK CANCER
Sponsor: Natera, Inc. • Aim: Knowledge-focused
Last updated May 26, 2026 03:13 UTC
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New MRI scans could reveal hidden secrets of head and neck cancers
Knowledge-focused Recruiting nowThis study is testing new MRI techniques to get more detailed information about head and neck and thyroid tumors. Researchers will compare these new scans with standard follow-up data to see if they can better predict how a tumor responds to treatment. The study involves 200 adul…
Matched conditions: HEAD AND NECK CANCER
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated May 26, 2026 03:12 UTC
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Nerve mapping study could unlock new sleep apnea therapy
Knowledge-focused Recruiting nowThis study looks at a nerve in the neck called the ansa cervicalis, which controls some throat muscles. Researchers want to measure its size and shape in 50 adults having neck surgery for head and neck cancer. They will also stimulate the nerve to see how much it moves the voice …
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated May 26, 2026 03:11 UTC
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Scientists investigate why head and neck cancer returns after radiation
Knowledge-focused Recruiting nowThis study looks at why head and neck cancer sometimes comes back after radiation treatment. Researchers will collect tissue and blood samples from 20 people who need robotic surgery for their cancer. By comparing the original tumor with the one that returned, they hope to learn …
Matched conditions: HEAD AND NECK CANCER
Sponsor: Royal Marsden NHS Foundation Trust • Aim: Knowledge-focused
Last updated May 26, 2026 03:11 UTC
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Scientists launch massive head and neck cancer tissue collection
Knowledge-focused Recruiting nowThis study collects tissue, saliva, and blood samples from up to 8,000 people with head and neck cancer and healthy volunteers. The samples and medical information are stored in a repository to help researchers better understand the disease and improve future treatments. No direc…
Matched conditions: HEAD AND NECK CANCER
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated May 26, 2026 03:11 UTC
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700-Patient study seeks early cancer clues in sputum and tissue
Knowledge-focused Recruiting nowThis study collects sputum and tissue samples from 700 people with precancerous lung changes or certain cancers (lung, head and neck, esophageal). Researchers look for genetic markers that might help detect cancer earlier. The goal is to build a tissue bank for future research, n…
Matched conditions: HEAD AND NECK CANCER
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated May 26, 2026 03:11 UTC
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Stanford launches quest to uncover head and neck Cancer's genetic secrets
Knowledge-focused Recruiting nowThis study aims to identify new genes and proteins involved in head and neck cancer. By analyzing tissue from 500 patients undergoing surgery at Stanford, researchers hope to understand how the disease develops and progresses. The ultimate goal is to pave the way for better diagn…
Matched conditions: HEAD AND NECK CANCER
Sponsor: Stanford University • Aim: Knowledge-focused
Last updated May 26, 2026 03:10 UTC
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AI tracks tumors in Real-Time, no markers needed
Knowledge-focused Recruiting nowThis study is developing an AI method to track the movement of tumors and nearby organs during radiation therapy without using physical markers. Researchers will use data from 300 patients receiving radiation for various cancers or heart arrhythmias to train and test the system. …
Matched conditions: HEAD AND NECK CANCER
Sponsor: University of Sydney • Aim: Knowledge-focused
Last updated May 26, 2026 03:10 UTC
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Blood samples collected to unlock cancer secrets
Knowledge-focused Recruiting nowThis study aims to collect blood samples (liquid biopsies) from 2,500 people with cancer or at high risk for cancer. The samples will be stored and used in future research to better understand how cancers grow and respond to treatment. No new treatments are being tested; the goal…
Matched conditions: HEAD AND NECK CANCER
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 26, 2026 03:04 UTC
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Scientists launch massive tissue bank to unlock secrets of cancer immunotherapy
Knowledge-focused Recruiting nowThis study collects blood, tumor, and other tissue samples from up to 1,250 people with head and neck, lung, or gastrointestinal cancers. The goal is to learn how the immune system changes during cancer treatments that affect immunity. Participants donate samples and fill out que…
Matched conditions: HEAD AND NECK CANCER
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Knowledge-focused
Last updated May 26, 2026 03:04 UTC
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Blood test may spare throat cancer patients from unnecessary radiation
Knowledge-focused Recruiting nowThis study looks at whether a simple blood test can tell which throat cancer patients can safely skip radiation after surgery. About 61 people with HPV-related throat cancer will have their blood tested before and after surgery. If the test is negative after surgery, they won't g…
Matched conditions: HEAD AND NECK CANCER
Phase: PHASE2 • Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated May 26, 2026 03:04 UTC
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7,000-Person cancer hunt: can DNA detect hidden disease before it returns?
Knowledge-focused Recruiting nowThis study is collecting blood, tissue, urine, and saliva from 7,000 people with many types of cancer to look for tiny bits of cancer DNA left after treatment. The goal is to find out if this DNA test can spot remaining cancer early and help doctors decide on next treatments. Par…
Matched conditions: HEAD AND NECK CANCER
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 26, 2026 03:04 UTC
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New study aims to unlock why immunotherapy fails most head and neck cancer patients
Knowledge-focused Recruiting nowThis study looks at why immunotherapy only helps about 15% of people with advanced head and neck cancer. Researchers will collect tissue and blood samples before and after treatment to find clues that predict who will benefit. The goal is to develop better, personalized treatment…
Matched conditions: HEAD AND NECK CANCER
Sponsor: Samsung Medical Center • Aim: Knowledge-focused
Last updated May 22, 2026 14:05 UTC
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Do hispanic cancer survivors know about lung screening? new study aims to find out.
Knowledge-focused Recruiting nowThis study looks at how much Hispanic/Latinx head and neck cancer survivors know about lung cancer screening and what stops them from getting screened. Researchers will use surveys and interviews with about 44 people. The goal is to find ways to improve screening rates in this gr…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: University of Miami • Aim: Knowledge-focused
Last updated May 22, 2026 14:03 UTC
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Mini device implanted in tumors could personalize cancer treatment
Knowledge-focused Recruiting nowThis early-phase study tests a small implantable device that delivers tiny amounts of different drugs directly into head and neck tumors. The goal is to see which drug works best for each person before full surgery. About 30 adults with certain head and neck cancers will take par…
Matched conditions: HEAD AND NECK CANCER
Phase: EARLY_PHASE1 • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated May 22, 2026 14:03 UTC
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Cancer biobank study aims to unlock secrets of tumors and immune system
Knowledge-focused Recruiting nowThis study is collecting tumor, blood, and plasma samples from over 1,000 people with certain cancers (ovarian, breast, head and neck, cervical, vulva, and sarcoma). The goal is to find new markers that link tumor genetics and immune response to how the disease behaves. Participa…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Institut Curie • Aim: Knowledge-focused
Last updated May 22, 2026 14:03 UTC
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New tool aims to predict cancer treatment toxicity in seniors
Knowledge-focused Recruiting nowThis study is testing a new tool to predict side effects from cancer treatment in elderly patients (70+) with advanced head and neck cancer. The goal is to see if the tool can help doctors choose safer treatments and improve outcomes. About 3 participants will be enrolled to vali…
Matched conditions: HEAD AND NECK CANCER
Sponsor: European Institute of Oncology • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC
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New study aims to catch malnutrition early in head and neck cancer patients
Knowledge-focused Recruiting nowThis study monitors the nutritional health of 57 head and neck cancer patients during radiotherapy. Researchers regularly check body composition, muscle strength, food intake, and quality of life to spot early signs of malnutrition. The goal is to understand nutrition-related cha…
Matched conditions: HEAD AND NECK CANCER
Sponsor: Marmara University • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC
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Massive european registry launched to crack the code on rare head and neck cancers
Knowledge-focused Recruiting nowThis study is building a large registry of people with rare head and neck cancers across Europe. Researchers will collect information from existing databases and doctors to understand how these cancers behave, what affects outcomes, and how well current treatments work. No new tr…
Matched conditions: HEAD AND NECK CANCER
Sponsor: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano • Aim: Knowledge-focused
Last updated May 22, 2026 13:50 UTC
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8,000-Patient study aims to sharpen cancer radiation with Real-Time MRI
Knowledge-focused Recruiting nowThis study is a large registry that will follow 8,000 cancer patients who receive radiation therapy guided by an MR-Linac, a machine that combines an MRI scanner with a radiation beam. The goal is to see if this technology helps people live longer, controls tumors better, and imp…
Matched conditions: HEAD AND NECK CANCER
Sponsor: UMC Utrecht • Aim: Knowledge-focused
Last updated May 20, 2026 11:55 UTC
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New study aims to boost cancer survivor Follow-Up care
Knowledge-focused Recruiting nowThis study tests whether giving head and neck cancer survivors a personalized survivorship care plan, along with a counseling session, helps them get better follow-up care. About 176 survivors will be randomly assigned to receive either the care plan or usual care. The goal is to…
Matched conditions: HEAD AND NECK CANCER
Phase: NA • Sponsor: Western University, Canada • Aim: Knowledge-focused
Last updated May 18, 2026 12:08 UTC
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Scientists investigate if microbiome imbalance fuels head and neck cancer
Knowledge-focused Recruiting nowThis study looks at whether an imbalance in the natural bacteria in your mouth and gut (called dysbiosis) plays a role in head and neck cancer. Researchers will collect stool and saliva samples from 60 adults—some with cancer and some without—to compare their microbiomes. The goa…
Matched conditions: HEAD AND NECK CANCER
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated May 18, 2026 12:00 UTC
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Scientists track fatigue in cancer patients to uncover hidden clues
Knowledge-focused Recruiting nowThis study looks at why cancer patients feel very tired during chemotherapy and radiation. Researchers will collect blood and stool samples from 125 adults with different cancers before, during, and after treatment. They aim to find links between fatigue and changes in genes and …
Matched conditions: HEAD AND NECK CANCER
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 14, 2026 12:02 UTC