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New skin flap could reduce surgery side effects for head and neck cancer patients

NCT ID NCT05757817

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 34 times

Summary

This study tests a new surgical technique called the external pudendal flap (STEPA flap) for rebuilding the mouth or throat after cancer removal. The goal is to see if it causes fewer complications at the area where the flap is taken from. About 40 patients will be followed for a year to check safety and healing.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre Antoine Lacassagne

    RECRUITING

    Nice, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chu Gui de Chauliac

    NOT_YET_RECRUITING

    Montpellier, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chu Purpan

    NOT_YET_RECRUITING

    Toulouse, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Universitaire Du Cancer Toulouse - Oncopole (Iuct-O)

    RECRUITING

    Toulouse, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

External pudendal artery flap (STEPA flap) surgical procedure

What this could lead to

If successful, this new surgical technique could offer a safer reconstruction option for head and neck cancer patients, with fewer complications at the donor site.

What could go wrong

This is an early-phase study with only 40 patients, so results may not apply broadly. There is a risk of flap failure or serious infection like Fournier gangrene.

Conditions

The condition(s) this trial relates to.

Head and Neck Neoplasms Mouth Neoplasms oropharynx cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.