ORAL CAVITY CANCER
Clinical trials for ORAL CAVITY CANCER explained in plain language.
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New combo aims to shrink head and neck tumors, sparing patients from radical surgery
Disease control Recruiting nowThis study tests giving chemotherapy and immunotherapy before standard surgery for head and neck cancer. The goal is to shrink tumors enough so that surgeons can do a less extensive operation, preserving speech, swallowing, and vision. About 75 adults with newly diagnosed, advanc…
Matched conditions: ORAL CAVITY CANCER
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Disease control
Last updated May 26, 2026 04:05 UTC
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New program aims to speed up cancer treatment after surgery
Disease control Recruiting nowThis study tests a program called ENDURE that helps head and neck cancer patients start radiation therapy within 6 weeks after surgery, as guidelines recommend. About 532 adults with certain types of head and neck cancer will take part. The program uses patient navigators to guid…
Matched conditions: ORAL CAVITY CANCER
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated May 26, 2026 03:56 UTC
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New drug cocktail aims to shrink Hard-to-Treat head and neck tumors
Disease control Recruiting nowThis study tests whether combining two drugs, sacituzumab govitecan and cetuximab, can shrink tumors in people with advanced head and neck cancer that has gotten worse after first-line therapy. About 40 adults with certain types of head and neck cancer will receive the drug combi…
Matched conditions: ORAL CAVITY CANCER
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 22, 2026 13:55 UTC
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New skin flap aims to reduce side effects after head and neck cancer surgery
Symptom relief Recruiting nowThis study tests a new surgical technique using a skin flap from the groin area to rebuild the mouth or throat after cancer removal. The goal is to see if this method causes fewer complications at the donor site compared to standard flaps. About 40 adults with head and neck cance…
Matched conditions: ORAL CAVITY CANCER
Phase: NA • Sponsor: Institut Claudius Regaud • Aim: Symptom relief
Last updated May 20, 2026 11:54 UTC
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Lab-Grown tumors may predict immunotherapy success in oral cancer
Knowledge-focused Recruiting nowThis study aims to see if researchers can create a personalized tumor model in the lab that predicts how a person's oral cancer will respond to immunotherapy (pembrolizumab) before surgery. About 20 adults with stage II-IVB oral cavity cancer will provide a biopsy sample and take…
Matched conditions: ORAL CAVITY CANCER
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated May 26, 2026 04:08 UTC
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Massive cancer registry aims to unlock secrets of the disease
Knowledge-focused Recruiting nowThis study is creating a huge collection of medical information and biological samples from adults with or at risk for many types of cancer, as well as healthy volunteers. The goal is to help researchers better understand cancer causes, improve early detection, and develop person…
Matched conditions: ORAL CAVITY CANCER
Sponsor: University of Nebraska • Aim: Knowledge-focused
Last updated May 22, 2026 14:02 UTC