Oral cavity cancer
Clinical trials for Oral cavity cancer explained in plain language.
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Could less radiation be better? new trial spares healthy neck tissue
Disease control OngoingThis phase 2 trial tests whether it is safe to skip radiation on one or both sides of the neck that show no signs of cancer after surgery. The goal is to reduce side effects like dry mouth and trouble swallowing without increasing the chance of cancer returning. The study include…
Matched conditions: ORAL CAVITY CANCER
Phase 2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jul 31, 2026 00:00 UTC
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New study tests safer pain relief for oral cancer patients
Symptom relief By invitation onlyThis study compares two pain management strategies for adults with oral cancer who have moderate to severe pain. One group receives the opioid tramadol, while the other gets a combination of pregabalin and naproxen sodium. Over 7 days, researchers measure pain reduction, side eff…
Matched conditions: ORAL CAVITY CANCER
Sponsor: Mayo Hospital Lahore • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Amazonian tree oil may soothe radiation mouth sores in cancer patients
Symptom relief OngoingThis early-phase study tests whether a mouthwash made from copaiba, a natural oil from the Amazon, can safely help prevent and treat painful mouth sores caused by radiation therapy in 20 adults with head and neck cancer. Researchers will find the highest safe dose and measure pai…
Matched conditions: ORAL CAVITY CANCER
Phase 1 • Sponsor: Instituto Nacional de Cancer, Brazil • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Natural mouthwash aimed to soothe radiation mouth sores, but study never started
Symptom relief CancelledThis study planned to test a mouthwash made from copaíba oil, a natural resin, to prevent and treat painful mouth sores (oral mucositis) in people with oral cancer undergoing radiation. The trial was set to include 40 patients, half using the copaíba mouthwash and half a placebo,…
Matched conditions: ORAL CAVITY CANCER
Phase 2 • Sponsor: Instituto Nacional de Cancer, Brazil • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC