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Massive cancer database aims to unlock secrets of the disease

NCT ID NCT02012699

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times

Summary

This study is building a huge registry of information and biological samples from adults with or at risk for many types of cancer, as well as healthy volunteers. Researchers will use this resource to study what causes cancer and how to better prevent, detect, and treat it. The registry is open to English and Spanish speakers aged 19 and older.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this registry could help researchers better understand cancer risks, improve early detection, and develop personalized treatments.
What could go wrong
This is an observational registry, not a treatment trial. It does not test any intervention, so direct patient benefits are not guaranteed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 999,999 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2013

Expected to finish

Dec 2099

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Any individual who meets the eligibility criteria will be invited to participate in iCaRe2.

Ages

19 to 110 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * Diagnosis/history of cancer * Risk for developing cancer or suspicious clinical findings * No history of cancer (normal control registry) * Able to provide informed consent * 19 years of age or older * English or Spanish speaking individuals Exclusion Criteria * Unable to provide informed consent because of cognitive impairment * Non-English or non-Spanish speaking individuals

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Anal cancer are added.

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Conditions

The condition(s) this trial relates to.

Adenomatous Polyposis Coli anal carcinoma anus neoplasm bile duct cancer bile duct neoplasm breast cancer breast neoplasm cancer of unknown primary site carcinoma of duodenum central nervous system cancer classic familial adenomatous polyposis colon carcinoma colonic neoplasm Colorectal Neoplasms, Hereditary Nonpolyposis duodenum cancer endometrial cancer endometrium neoplasm esophageal cancer Esophageal Neoplasms gallbladder cancer gallbladder neoplasm gastric cancer gastric neoplasm gastrointestinal stromal tumor hypopharyngeal carcinoma hypopharynx cancer kidney cancer laryngeal carcinoma laryngeal neoplasm leukemia lip cancer liver cancer Liver Neoplasms lung cancer lung neoplasm Lynch syndrome malignant pancreatic neoplasm melanoma mesothelioma monoclonal gammopathy Mouth Neoplasms nasal cavity cancer nasopharyngeal carcinoma, susceptibility to, 1 nasopharyngeal neoplasm Neoplasms, Unknown Primary neuroendocrine neoplasm oral cavity cancer oropharyngeal carcinoma oropharynx cancer ovarian cancer pancreatic neoplasm paranasal sinus cancer Paranasal Sinus Neoplasms penile cancer penile neoplasm peritoneal neoplasm plasma cell myeloma plasma cell neoplasm prostate cancer rectal cancer rectal neoplasm salivary gland cancer sarcoma skin cancer skin neoplasm small intestine cancer testicular cancer thymus cancer Thymus Neoplasms thyroid cancer Thyroid Neoplasms Thyroid Nodule ureter cancer urethra cancer Urethral Neoplasms urinary bladder carcinoma Urinary Bladder Neoplasms vaginal cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    42 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Advent Health

    RECRUITING

    Greenwood Village, Colorado, 80111, United States

  • Aultman Alliance Community Hospital

    RECRUITING

    Alliance, Ohio, 44601, United States

  • Aultman Hospital

    RECRUITING

    Canton, Ohio, 44710, United States

  • Bellin Memorial Hospital

    RECRUITING

    Green Bay, Wisconsin, 54305, United States

  • Bozeman Health Deaconess Hospital

    RECRUITING

    Bozeman, Montana, 59715, United States

  • C.R. Wood Cancer Center, Glens Falls Hospital

    RECRUITING

    Glens Falls, New York, 12801, United States

  • Cape Fear Valley Health System

    RECRUITING

    Fayetteville, North Carolina, 28304, United States

  • Covenant Medical Center, Inc

    RECRUITING

    Waterloo, Iowa, 50702, United States

  • Essentia Health

    RECRUITING

    Fargo, North Dakota, 58103, United States

  • Essentia Health - Duluth Clinic

    RECRUITING

    Duluth, Minnesota, 55805, United States

  • Essentia Health-St. Joseph's Medical Center

    RECRUITING

    Brainerd, Minnesota, 56401, United States

  • Faith Regional Health Services, Carson Cancer Center

    RECRUITING

    Norfolk, Nebraska, 68701, United States

  • Faxton St. Luke's Healthcare, Mohawk Valley

    RECRUITING

    Utica, New York, 13501, United States

  • Florida Hospital DeLand

    RECRUITING

    DeLand, Florida, 32720, United States

  • Florida Hospital FISH

    RECRUITING

    Orange City, Florida, 32763, United States

  • Florida Hospital Flagler

    RECRUITING

    Palm Coast, Florida, 32164, United States

  • Florida Hospital Memorial Medical Center

    RECRUITING

    Daytona Beach, Florida, 32117, United States

  • Great Plains Regional Medical Center

    RECRUITING

    North Platte, Nebraska, 69101, United States

  • Hartford HealthCare Cancer Institute at Manchester Medical Hospital

    RECRUITING

    Manchester, Connecticut, 06040, United States

  • Heartland Regional Medical Center dba Mosaic Life Care

    RECRUITING

    Saint Joseph, Missouri, 64507, United States

  • Holyoke Medical Center

    RECRUITING

    Holyoke, Massachusetts, 01040, United States

  • Lake Region Healthcare

    RECRUITING

    Fergus Falls, Minnesota, 56537, United States

  • Mary Lanning Healthcare, Morrison Cancer Center

    RECRUITING

    Hastings, Nebraska, 68901, United States

  • Methodist Estabrook Cancer Center

    RECRUITING

    Omaha, Nebraska, 68114, United States

  • Methodist Jennie Edmundson Hospital

    RECRUITING

    Council Bluffs, Iowa, 51503, United States

  • Nebraska Methodist Health System

    RECRUITING

    Omaha, Nebraska, 68114, United States

  • North Kansas City Hospital

    RECRUITING

    North Kansas City, Missouri, 64116, United States

  • Northwest Hospital

    RECRUITING

    Randallstown, Maryland, 21133, United States

  • Parkview Research Center

    RECRUITING

    Fort Wayne, Indiana, 46845, United States

  • Riverwood Healthcare Center

    RECRUITING

    Aitkin, Minnesota, 56431, United States

  • Rush-Copley Cancer Care Center

    RECRUITING

    Aurora, Illinois, 60504, United States

  • Rush-Copley Healthcare Center

    RECRUITING

    Yorkville, Illinois, 60560, United States

  • Saint Luke's Cancer Instititute - South

    RECRUITING

    Overland Park, Kansas, 66213, United States

  • Saint Luke's Cancer Institute

    RECRUITING

    Kansas City, Missouri, 64111, United States

  • Saint Luke's Cancer Institute, East

    RECRUITING

    Kansas City, Missouri, 64086, United States

  • Saint Luke's Cancer Institute, Kansas City North

    RECRUITING

    Kansas City, Missouri, 64118, United States

  • Saint Luke's Cancer Institute, Liberty

    RECRUITING

    Liberty, Missouri, 64068, United States

  • St. Luke's Hospital of Duluth

    RECRUITING

    Duluth, Minnesota, 55805, United States

  • Tallahassee Memorial Hospital

    RECRUITING

    Tallahassee, Florida, 32308, United States

  • Trinity Hospital Cancer Care Center

    RECRUITING

    Minot, North Dakota, 58701, United States

  • University of Nebraska Medical Center

    RECRUITING

    Omaha, Nebraska, 68198, United States

  • William E. Kahlert Regional Cancer Center

    RECRUITING

    Westminster, Maryland, 21157, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.