FAMILIAL ADENOMATOUS POLYPOSIS
Clinical trials for FAMILIAL ADENOMATOUS POLYPOSIS explained in plain language.
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New drug aims to tame polyp growth in rare genetic condition
Disease control Recruiting nowThis study tests an experimental drug called REC-4881 in 67 adults with familial adenomatous polyposis (FAP), a genetic condition that causes many polyps in the gut and raises cancer risk. The goal is to see if the drug can safely reduce the number and size of polyps. Participant…
Matched conditions: FAMILIAL ADENOMATOUS POLYPOSIS
Phase: PHASE1, PHASE2 • Sponsor: Recursion Pharmaceuticals Inc. • Aim: Disease control
Last updated May 26, 2026 04:47 UTC
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New personalized plan aims to stop cancer in FAP patients after surgery
Disease control Recruiting nowThis study tests a personalized monitoring and treatment plan for 1,000 adults with familial adenomatous polyposis (FAP) who have had their colon removed. The goal is to see if tailored check-ups and early removal of polyps can keep the rate of advanced growths or cancer below 5%…
Matched conditions: FAMILIAL ADENOMATOUS POLYPOSIS
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Disease control
Last updated May 26, 2026 04:35 UTC
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Tailored surveillance aims to prevent cancer in FAP patients
Disease control Recruiting nowThis study tests a personalized plan for monitoring and treating polyps in the stomach and duodenum of people with Familial Adenomatous Polyposis (FAP). The goal is to see if a customized approach can reduce the risk of advanced growths or cancer. About 1,000 adults with FAP will…
Matched conditions: FAMILIAL ADENOMATOUS POLYPOSIS
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Disease control
Last updated May 26, 2026 04:33 UTC
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New drug aims to cut polyp burden in inherited colon cancer condition
Disease control Recruiting nowThis study tests a drug called TPST-1495 in 38 people with familial adenomatous polyposis (FAP), an inherited condition that causes many polyps in the colon and small bowel and raises colon cancer risk. The drug works by blocking certain signals that help polyps grow. The main go…
Matched conditions: FAMILIAL ADENOMATOUS POLYPOSIS
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 20, 2026 11:57 UTC
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Can treadmill workouts stop polyps from coming back?
Prevention Recruiting nowThis study looks at whether different amounts of home treadmill exercise can help prevent colorectal polyps from returning in people with Familial Adenomatous Polyposis (FAP). About 32 participants will follow a personalized exercise plan for 26 weeks. Small tissue samples, blood…
Matched conditions: FAMILIAL ADENOMATOUS POLYPOSIS
Phase: NA • Sponsor: University of Michigan Rogel Cancer Center • Aim: Prevention
Last updated May 26, 2026 04:48 UTC
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Could a Cancer-Killing pill stop colon cancer before it starts?
Prevention Recruiting nowThis early-stage trial tests the safety of a drug called ONC201 (dordaviprone) in 36 adults at high risk for colorectal cancer due to familial adenomatous polyposis (FAP) or a history of many polyps. The drug aims to kill precancerous cells without harming healthy ones. If succes…
Matched conditions: FAMILIAL ADENOMATOUS POLYPOSIS
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Prevention
Last updated May 26, 2026 04:38 UTC
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Supplement could slash colonoscopies for rare genetic condition
Prevention Recruiting nowThis study tests whether taking a beta-hydroxybutyrate (BHB) supplement can safely slow or stop the growth of intestinal polyps in people with Familial Adenomatous Polyposis (FAP), a genetic condition that often leads to colon cancer. About 20 adults with FAP will take BHB daily …
Matched conditions: FAMILIAL ADENOMATOUS POLYPOSIS
Phase: NA • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Prevention
Last updated May 22, 2026 14:02 UTC
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New tool aims to spot cancer risk earlier in rare genetic condition
Knowledge-focused Recruiting nowThis study aims to create a more accurate way to predict duodenal cancer in people with familial adenomatous polyposis (FAP), a genetic condition that raises colon and duodenal cancer risk. Researchers will analyze endoscopy images from 300 participants to build and test two risk…
Matched conditions: FAMILIAL ADENOMATOUS POLYPOSIS
Sponsor: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano • Aim: Knowledge-focused
Last updated May 26, 2026 04:42 UTC
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Massive cancer registry aims to unlock secrets of the disease
Knowledge-focused Recruiting nowThis study is creating a huge collection of medical information and biological samples from adults with or at risk for many types of cancer, as well as healthy volunteers. The goal is to help researchers better understand cancer causes, improve early detection, and develop person…
Matched conditions: FAMILIAL ADENOMATOUS POLYPOSIS
Sponsor: University of Nebraska • Aim: Knowledge-focused
Last updated May 22, 2026 14:02 UTC
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Hunt for hidden cancer genes in families
Knowledge-focused Recruiting nowThis research study aims to discover new genes that may increase the risk of childhood cancer. Researchers will collect blood samples and health information from 1,500 people in families where cancer clusters. The goal is to build a registry and sample bank to help future diagnos…
Matched conditions: FAMILIAL ADENOMATOUS POLYPOSIS
Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated May 19, 2026 12:00 UTC