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Supplement could slash colonoscopies for rare genetic condition

NCT ID NCT06578637

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 30 times

Summary

This study tests whether taking a beta-hydroxybutyrate (BHB) supplement can safely slow or stop the growth of intestinal polyps in people with Familial Adenomatous Polyposis (FAP), a genetic condition that often leads to colon cancer. About 20 adults with FAP will take BHB daily for several months. Researchers will check if it is well-tolerated and if it raises BHB levels in the blood, which may help prevent polyps and reduce the need for frequent colonoscopies or surgery.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Abramson Cancer Center of the University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.