FAP
Clinical trials for FAP explained in plain language.
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New drug combo targets tough tumors in early trial
Disease control Recruiting nowThis early-phase study tests a new drug, [177Lu]Lu-OncoFAP-23, alone or with another drug (L19-IL2), in people with advanced solid tumors that have a protein called FAP. The main goal is to check safety and find the best dose. About 56 adults whose cancer has worsened after stand…
Matched conditions: FAP
Phase: PHASE1 • Sponsor: Philogen S.p.A. • Aim: Disease control
Last updated May 26, 2026 02:22 UTC
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New drug FOG-001 targets Hard-to-Treat cancers in early trial
Disease control Recruiting nowThis study tests a new drug, FOG-001, in about 595 people with advanced solid tumors that have not responded to other treatments. The goal is to see if FOG-001 is safe and can shrink tumors or slow their growth. The trial focuses on several cancer types, including colorectal, pro…
Matched conditions: FAP
Phase: PHASE1, PHASE2 • Sponsor: Parabilis Medicines, Inc. • Aim: Disease control
Last updated May 11, 2026 20:46 UTC
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Supplement could slash colonoscopies for rare genetic condition
Prevention Recruiting nowThis study tests whether taking a beta-hydroxybutyrate (BHB) supplement can safely slow or stop the growth of intestinal polyps in people with Familial Adenomatous Polyposis (FAP), a genetic condition that often leads to colon cancer. About 20 adults with FAP will take BHB daily …
Matched conditions: FAP
Phase: NA • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Prevention
Last updated May 22, 2026 14:02 UTC
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New tool aims to spot cancer risk earlier in rare genetic condition
Knowledge-focused Recruiting nowThis study aims to create a more accurate way to predict duodenal cancer in people with familial adenomatous polyposis (FAP), a genetic condition that raises colon and duodenal cancer risk. Researchers will analyze endoscopy images from 300 participants to build and test two risk…
Matched conditions: FAP
Sponsor: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano • Aim: Knowledge-focused
Last updated May 26, 2026 02:24 UTC