Tailored plan aims to prevent cancer in inherited polyposis patients

NCT ID NCT04677998

Recruiting now Disease control Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Source: ClinicalTrials.gov ↗

First seen Feb 20, 2026 · Last updated Jun 18, 2026 · Updated 21 times

Summary

This study tests a personalized approach to monitor and treat polyps in the stomach and duodenum of people with familial adenomatous polyposis (FAP), a genetic condition that raises cancer risk. Researchers will enroll 1,000 adults with FAP to see if tailored surveillance and endoscopic removal can reduce advanced growths and cancer. The goal is to improve long-term outcomes without requiring lifelong medication.

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Contacts and locations

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Locations

Academic Medical Centre
RECRUITING

Amsterdam, North Holland, 1105AZ, Netherlands

Contact

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MD Anderson
RECRUITING

Houston, Texas, 77030, United States

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Contact

Conditions

The condition(s) this trial relates to.

Adenomatous Polyposis Coli classic familial adenomatous polyposis carcinoma of duodenum prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FAMILIAL ADENOMATOUS POLYPOSIS