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New study explores why cancer patients lose their appetite

NCT ID NCT06600295

Knowledge-focused Sponsor: Centre Hospitalier Universitaire Dijon Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how cancer and its treatments change a person's sense of taste and smell, and how that affects their eating and nutrition. Researchers will follow 306 people newly diagnosed with cancer of the mouth, throat, colon, or liver. They will use questionnaires, taste tests, and strength measurements to understand these changes and find ways to prevent malnutrition.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better understand why cancer patients lose their appetite and develop ways to prevent malnutrition.
What could go wrong
This is an observational study, not a treatment trial. It will not directly test any new drug or therapy, so it cannot lead to a cure or immediate symptom relief.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 306 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2024

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Eligible patients will be identified : * at the department\'s multidisciplinary consultation meetings * during consultations with their referring doctor (ENT or gastroenterologist)

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Patient : * With newly diagnosed cancer of the oropharynx, oral cavity, colon or liver (at any stage). * For whom first-line treatment has been decided including radiotherapy, chemotherapy, immunotherapy and/or surgery. * Able to follow all study procedures in accordance with the protocol. * Have given their oral, free and informed consent to participate in the study. Exclusion Criteria: * Person not affiliated with national health insurance system * Person subject to a legal protection measure (curatorship, guardianship) * Pregnant women, women in labour or breastfeeding mothers * Adults who is unable to give consent * Minors * Person unable to read, speak, write and understand French * Patients with neuro-cognitive disorders (post-stroke, dyslexia, dyspraxia) or neuro-psychiatric disorders (dementia, autism) that make it impossible to assess taste sensoriality. * Patients with olfactory or gustatory disorders documented prior to the disease * Patient with another cancer currently being treated * Patients with a systemic disease or physical trauma affecting taste perception * Patients with kidney failure * Patients with sinonasal polyposis * Patients undergoing immunosuppressive treatment * Patients with an estimated life expectancy of less than 3 months

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Conditions

The condition(s) this trial relates to.

colon carcinoma liver cancer oral cavity cancer oropharyngeal carcinoma oropharynx cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Newly diagnosed cancer of the oropharynx, oral cavity, colon or liver

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Chu Dijon Bourgogne

    RECRUITING

    Dijon, 21000, France

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