New skin flap could reduce surgery side effects for head and neck cancer patients

NCT ID NCT05757817

Recruiting now Disease control Sponsor: Institut Claudius Regaud Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests a new surgical technique using a thin skin flap from the groin area to rebuild the mouth or throat after cancer removal. The goal is to see if it causes fewer problems at the donor site compared to standard flaps. Forty adults with head and neck cancer will be followed for a year to check for complications like flap failure or infection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: External pudendal artery flap (STEPA flap) surgical procedure
What this could lead to: If successful, this could offer a safer reconstructive option for head and neck cancer patients, with fewer complications at the donor site.
What could go wrong: This is an early-phase study with only 40 patients, so results may not apply broadly. Risks include flap failure or rare infection (Fournier gangrene).

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms head and neck squamous cell carcinoma Mouth Neoplasms oral cavity cancer oral cavity squamous cell carcinoma oropharynx cancer oropharynx squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEAD AND NECK CANCER ORAL CAVITY CANCER OROPHARYNX CANCER

Contacts and locations

Locations

Centre Antoine Lacassagne
RECRUITING

Nice, France
Chu Gui de Chauliac
NOT_YET_RECRUITING

Montpellier, France
Chu Purpan
NOT_YET_RECRUITING

Toulouse, France
Institut Universitaire Du Cancer Toulouse - Oncopole (Iuct-O)
RECRUITING

Toulouse, France

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