Home workouts via video calls could ease cancer side effects
NCT ID NCT07059884
First seen Jun 27, 2026 · Last updated Aug 06, 2026 · Updated 5 times
Summary
This study tests whether cancer patients can complete a supervised exercise program from home using video calls. The program includes resistance training with dumbbells and aerobic exercise. Researchers want to see if this approach is practical and helps patients maintain function and reduce disability during chemotherapy.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- exercise program (supervised resistance and unsupervised aerobic exercise via telehealth)
- What this could lead to
- If it works, this could offer a convenient way for cancer patients to exercise at home during treatment, potentially reducing fatigue and preserving strength.
- What could go wrong
- This is an early feasibility study with only 104 participants, so it may not prove that the program improves health outcomes. Results may not apply to all cancer types or treatments.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 104 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2026
- Expected to finish
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Aug 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * REGISTRATION ELIGIBILITY CRITERIA (STEP 1): Participants must have histologically confirmed diagnosis of one of the following cancers: anus, bladder, breast, cervix, colon/rectum, endometrium, esophagus, gallbladder, head/neck, kidney, liver, lung, ovary, pancreas, prostate, sarcoma, stomach * REGISTRATION ELIGIBILITY CRITERIA (STEP 1): Participants must be initiating outpatient cytotoxic chemotherapy for curative intent of at least 10 weeks duration (with or without concurrent radiation, immunotherapy, or other targeted therapy). Patients must be enrolled and baseline measures collected on or before administration of their second cycle of cytotoxic therapy. Patients receiving outpatient cytotoxic chemotherapy for curative intent in the neoadjuvant or adjuvant setting are eligible. Patients receiving definitive chemoradiation for the tumors listed above, are also eligible. Regimens of immunotherapy or monoclonal antibodies ONLY are not eligible * REGISTRATION ELIGIBILITY CRITERIA (STEP 1): Age 18-64 years * REGISTRATION ELIGIBILITY CRITERIA (STEP 1): Patients cannot have metastatic cancer * REGISTRATION ELIGIBILITY CRITERIA (STEP 1): Patients cannot have documentation in the medical record of severe cardiovascular, respiratory or musculoskeletal disease or joint problems that preclude moderate physical activity. Examples would include unstable angina, recent myocardial infarction, oxygen-dependent pulmonary disease, and osteoarthritis requiring imminent joint replacement. Moderate arthritis that does not preclude physical activity is not a reason for ineligibility * REGISTRATION ELIGIBILITY CRITERIA (STEP 1): Patients cannot be pregnant, because this study involves remotely delivered exercise, and cannot be breast-feeding as patients must be receiving cytotoxic chemotherapy, during which breast-feeding is contraindicated * REGISTRATION ELIGIBILITY CRITERIA (STEP 1): Patients cannot have documentation in the medical record of current alcohol, substance abuse, or dementia * REGISTRATION ELIGIBILITY CRITERIA (STEP 1): Engaged in full time gainful employment of at least 30 hours per week at the time of cancer diagnosis * REGISTRATION ELIGIBILITY CRITERIA (STEP 1): Currently no self-report of engagement in competitive sports (e.g. not training for running races, triathlons, etc.) AND no self-report of twice weekly progressive resistance exercise training for at least 3 consecutive months within the past year * REGISTRATION ELIGIBILITY CRITERIA (STEP 1): Self-reported ability to walk for 6 minutes (use of assistive devices will be allowed) * REGISTRATION ELIGIBILITY CRITERIA (STEP 1): Not participating in another weight loss, physical activity, or dietary intervention clinical trial * REGISTRATION ELIGIBILITY CRITERIA (STEP 1): Predicted 6MWT distance of 550 meters or less * REGISTRATION ELIGIBILITY CRITERIA (STEP 1): Concurrent enrollment in treatment or supportive care trials (other than those focused on weight loss or exercise) is allowed with the permission of the Alliance Executive Officer and both studies' study chairs * REGISTRATION ELIGIBILITY CRITERIA (STEP 1): Eligibility is restricted to individuals who can comprehend and read English given that participation in the study will require the ability to read intervention materials and work with a coach through telehealth sessions * REGISTRATION ELIGIBILITY CRITERIA (STEP 1): The trial is unable to accommodate the needs of deaf or blind participants as the study relies on language and visualization of exercise through telehealth sessions * CLINICAL STAKEHOLDER ELIGIBILITY CRITERIA: Clinicians and research staff from enrolling sites who meet following criterion will be deemed eligible to participate as a clinical stakeholder: \* Providing clinical care for participating patients on this study * CLINICAL STAKEHOLDER ELIGIBILITY CRITERIA: Ability to speak and understand English Exclusion Criteria: \-
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The places running it
18 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Show contact details
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Genom att skicka in godkänner du våra Användarvillkor
Study contacts
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Contact
Email: •••••@•••••
Locations
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
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IRMC Cancer Center
RECRUITINGIndiana, Pennsylvania, 15701, United States
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Kaiser Permanente Dublin
RECRUITINGDublin, California, 94568, United States
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Kaiser Permanente Fresno Orchard Plaza
RECRUITINGFresno, California, 93720, United States
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Kaiser Permanente-Fremont
RECRUITINGFremont, California, 94538, United States
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Kaiser Permanente-Modesto
RECRUITINGModesto, California, 95356, United States
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Kaiser Permanente-Oakland
RECRUITINGOakland, California, 94611, United States
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Kaiser Permanente-Santa Teresa-San Jose
RECRUITINGSan Jose, California, 95119, United States
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Kaiser Permanente-South Sacramento
RECRUITINGSacramento, California, 95823, United States
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Kaiser Permanente-Vallejo
RECRUITINGVallejo, California, 94589, United States
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Kaiser San Rafael-Gallinas
RECRUITINGSan Rafael, California, 94903, United States
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Novant Health Cancer Institute - Kernersville
RECRUITINGKernersville, North Carolina, 27284, United States
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Novant Health Cancer Institute - Mount Airy
RECRUITINGMount Airy, North Carolina, 27030, United States
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Novant Health Forsyth Medical Center
RECRUITINGWinston-Salem, North Carolina, 27103, United States
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UPMC Cancer Center at UPMC Northwest
RECRUITINGSeneca, Pennsylvania, 16346, United States
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UPMC Hillman Cancer Center
RECRUITINGPittsburgh, Pennsylvania, 15232, United States
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UPMC Hillman Cancer Center - New Castle
RECRUITINGNew Castle, Pennsylvania, 16105, United States
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UPMC Hillman Cancer Center at Butler Health System
RECRUITINGButler, Pennsylvania, 16001, United States
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