Last-Resort drug opens for advanced cancer patients with specific gene mutations
NCT ID NCT04566393
First seen Jan 31, 2026 · Last updated Apr 30, 2026 · Updated 12 times
Summary
This program offers ulixertinib, an experimental drug, to adults with advanced solid tumors that have specific gene changes (MAPK pathway mutations) and who have not responded to or exhausted other treatments. The goal is to provide compassionate access to possibly control the cancer when no standard options remain. Participants may take ulixertinib alone or with other tolerable drugs.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Atlantic Health System/Overlook Medical Center
AVAILABLESummit, New Jersey, 07901, United States
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Cancer Partners of Nebraska
AVAILABLELincoln, Nebraska, 68510, United States
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Clearview Cancer Institute
AVAILABLEHuntsville, Alabama, 35805, United States
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Hirschfeld Oncology
AVAILABLEBrooklyn, New York, 11206, United States
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Hoag Memorial Hospital Presbyterian
AVAILABLENewport Beach, California, 92663, United States
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Hunterdon Hematology Oncology
AVAILABLEFlemington, New Jersey, 08822, United States
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Infirmary Cancer Care
AVAILABLEMobile, Alabama, 36604, United States
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Lake Region Healthcare
AVAILABLEFergus Falls, Minnesota, 56537, United States
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Lehigh Valley Health Network
AVAILABLEAllentown, Pennsylvania, 18103, United States
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MD Anderson
AVAILABLEHouston, Texas, 77030, United States
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Mary Bird Perkins Cancer Center
AVAILABLEBaton Rouge, Louisiana, 70809, United States
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MedStar Georgetown University Hospital
AVAILABLEWashington D.C., District of Columbia, 20007, United States
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Mercy Medical Center
AVAILABLECedar Rapids, Iowa, 52403, United States
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Monmouth Medical Center
AVAILABLELong Branch, New Jersey, 07740, United States
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Nebraska Hematology Oncology
AVAILABLELincoln, Nebraska, 68506, United States
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Oakland Macomb Cancer Specialists
AVAILABLESterling Heights, Michigan, 48314, United States
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Orlando Health
AVAILABLEOrlando, Florida, 32806, United States
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Our Lady of the Lake Hospital
AVAILABLEBaton Rouge, Louisiana, 70808, United States
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PCR Oncology
AVAILABLEArroyo Grande, California, 93420, United States
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Providence Saint John's Health Center
AVAILABLESanta Monica, California, 90404, United States
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Stony Brook Cancer Center
AVAILABLEStony Brook, New York, 11794, United States
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The Christ Hospital
AVAILABLECincinnati, Ohio, 45219, United States
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The Minniti Center for Medical Oncology and Hematology
AVAILABLEMickleton, New Jersey, 08056, United States
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UTHealth - Tyler
AVAILABLETyler, Texas, 75701, United States
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UTHealth Houston
AVAILABLEHouston, Texas, 77030, United States
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Unity Point Health - St. Lukes Hospital
AVAILABLECedar Rapids, Iowa, 52403, United States
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xCures Inc.
AVAILABLESan Francisco, California, 94105, United States
Conditions
Explore the condition pages connected to this study.