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Scientists investigate whether tiny microbes fuel head and neck tumors

NCT ID NCT05837221

First seen Feb 27, 2026 · Last updated Jun 22, 2026 · Updated 20 times

Summary

This study looks at whether changes in the bacteria living in your mouth and gut (the microbiome) are linked to head and neck cancer. Researchers will collect stool and saliva samples from 60 people—half with cancer and half without—to compare their microbial makeup. The goal is to understand if these microbes play a role in cancer development, which could lead to new ways to diagnose or treat the disease in the future.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Colorado Cancer Center

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could reveal how bacteria in the mouth and gut influence head and neck cancer, potentially pointing to new ways to detect or treat the disease.

What could go wrong

This is an early observational study with only 60 participants. It is designed to gather information, not to test a treatment, so direct benefits for patients are not expected.

Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms lip and oral cavity carcinoma lip cancer Mouth Neoplasms oral cavity squamous cell carcinoma pharynx cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.