Sanofi

This study tested a new vaccine designed to protect against the Omicron JN.1 variant of COVID-19. About 120 adults aged 65 and older, and teens and adults aged 12 to 64 with health conditions that increase COVID-19 risk, received one dose. Researchers checked how well the vaccine…

This study tested a single combination vaccine that aims to protect against both COVID-19 and influenza at the same time. About 980 adults aged 50 and older received either the combo shot, a flu shot alone, a COVID-19 shot alone, or both shots separately. Researchers monitored sa…

This study tested a single combination vaccine that targets both COVID-19 and influenza in adults aged 50 and older. About 980 participants received either the combo shot, the flu vaccine alone, the COVID-19 vaccine alone, or separate shots in each arm. Researchers monitored safe…

This early-stage study tested six different mRNA vaccine formulations against respiratory syncytial virus (RSV) in 240 healthy adults aged 18 to 49. The goal was to check safety and how well the vaccines trigger an immune response. Each participant received a single shot and was …

This study tested a new yellow fever vaccine (vYF) to see if it is as safe as the current licensed vaccine (YF-VAX). A total of 640 healthy adults aged 18 to 60 received a single shot of either vaccine. Researchers monitored side effects like pain, fever, and headache for about 6…

This early-stage study tested the safety and immune response of new vaccines that combine protection against flu, RSV, hMPV, and PIV3 in healthy adults aged 18 to 49. Participants received a single shot of one of several vaccine formulas. The goal was to see if these combination …

This Phase 3 trial tested a new single-dose vaccine (MenACYW) against an existing one (Menactra) in 360 healthy people aged 2 to 55. The goal was to see if the new vaccine triggers a similar or better immune response to four types of meningococcal bacteria. Results showed the new…

This study tested three new pneumococcal vaccine formulations in 750 healthy adults aged 50 to 84. The goal was to see how well they trigger an immune response and how safe they are compared to two existing vaccines. Participants received a single shot, and researchers measured a…

This study tested a new drug called amlitelimab, given as a shot under the skin, for people aged 12 and older with moderate-to-severe atopic dermatitis (eczema) that wasn't controlled by creams. The trial included 643 participants and compared amlitelimab to a placebo, while ever…

This Phase 3 study tests amlitelimab, an injected drug, in 589 people aged 12 and older with moderate-to-severe atopic dermatitis (eczema) that hasn't responded well to topical treatments. The goal is to see if amlitelimab can clear or nearly clear the skin and reduce eczema seve…

This trial is testing whether an experimental oral drug called rilzabrutinib can reduce the itching and hives in adults with chronic spontaneous urticaria (CSU) — a condition where hives appear without a clear trigger — even when standard antihistamines haven't helped. Participan…

This trial tests whether dupilumab, an injectable drug that blocks certain inflammatory signals, can reduce sinus swelling and improve symptoms like loss of smell and runny nose in adults with chronic sinusitis who do not have nasal polyps. Participants receive either dupilumab o…

This study tracks adults with relapsed or refractory multiple myeloma who are already receiving isatuximab as part of their routine care. Researchers will measure how many patients respond to treatment, how long the response lasts, and how the drug affects quality of life and sid…

This study tested a new medicine called amlitelimab, given as a shot under the skin, for people aged 12 and older with moderate-to-severe eczema that didn't get better with creams or other treatments. The goal was to see if it can clear or nearly clear the skin and reduce itching…

This study tests whether a connected smartphone app called Health2Sync helps adults with type 2 diabetes who use basal insulin achieve better blood sugar control. The app syncs blood glucose readings and shares them with doctors, who can then adjust insulin doses. Researchers com…

This phase 2 study tests whether rilzabrutinib, an oral medication, can reduce eczema severity in adults with moderate-to-severe atopic dermatitis who do not respond well to or cannot tolerate topical corticosteroids. Participants receive either rilzabrutinib or a placebo for 16 …

This study is testing whether men can safely use tadalafil 5 mg (Cialis) for erectile dysfunction without a prescription. Participants will use a digital health survey to check if the drug is right for them before buying it. The goal is to see if people follow dosing instructions…

This study tests a fixed-dose combination of insulin glargine and lixisenatide (iGlarLixi) in 105 adults with type 2 diabetes whose blood sugar is not well controlled on oral drugs or other injectables. The main goal is to check safety and side effects, while also measuring chang…

This study tested the safety and effectiveness of eliglustat, an oral medication, in 57 children aged 2 to 17 with Gaucher disease types 1 and 3. Some children also received the standard enzyme therapy imiglucerase. Researchers measured how the drug moves through the body, side e…

This study followed 105 teenagers with severe uncontrolled asthma who were starting treatment with dupilumab (Dupixent). Researchers tracked their asthma control, flare-ups, and safety over one year. The goal was to see if this medication helps teens manage their condition better…

This study tested the drug belumosudil in Chinese teenagers aged 12 to 18 with chronic graft-versus-host disease (cGVHD), a complication after stem cell transplant. The goal was to see how well the drug works and how safe it is for those who didn't respond to steroids. Six partic…

This study followed 305 Canadian adults and children (ages 6+) with moderate-to-severe eczema who were prescribed Dupixent as part of their routine care. Researchers measured how many patients achieved at least a 75% reduction in eczema severity after 6, 12, and 18 months. The go…

This study tests a drug called lunsekimig in adults with chronic sinusitis and nasal polyps that persist despite using steroid sprays. The drug is given as a shot under the skin every few weeks. Researchers will measure changes in polyp size and nasal congestion over 24 weeks. Th…

This study tested a drug called itepekimab in over 1,200 people with moderate-to-severe COPD who were either former or current smokers. The goal was to see if it could reduce the number of serious flare-ups and improve lung function compared to a placebo. The drug works by blocki…

This study tested a new antibody drug called itepekimab in over 1,100 former smokers with moderate-to-severe COPD. The goal was to see if it could reduce the number of sudden worsening episodes (exacerbations) and improve breathing. Participants received either the drug or a plac…

This study followed 3 people with acid sphingomyelinase deficiency (ASMD) who had already completed earlier trials of olipudase alfa. The goal was to monitor safety and side effects while they continued receiving the enzyme replacement therapy every two weeks until the drug was o…

This Phase 2 trial tested amlitelimab, an injectable drug, in 437 adults with moderate-to-severe asthma. Participants received either amlitelimab or a placebo alongside their usual asthma medications. The study measured how well the drug reduced severe asthma attacks and improved…

This Phase 2b study tested lunsekimig, an injectable drug, in 685 adults with moderate-to-severe asthma. Participants received either lunsekimig or a placebo alongside their usual asthma medications. The goal was to see if lunsekimig could reduce asthma attacks and improve breath…

This study tested a drug called itepekimab in 312 adults with bronchiectasis (a lung condition causing chronic cough and infections). The goal was to see if it could reduce the number of moderate or severe lung flare-ups compared to a placebo. Participants received either the dru…

This early-stage trial tested an inhaled drug called MRT5005 in 42 adults with cystic fibrosis. The goal was to check safety and see if it could improve lung function. Participants received either the drug or a placebo by nebulizer. The study is completed, and results will help d…

This study tested whether adding the drug isatuximab to a standard two-drug regimen (carfilzomib and dexamethasone) helps people with multiple myeloma that has returned or stopped responding to prior treatments. 302 adults who had already received 1 to 3 prior therapies took part…

This phase 2 study tested a new drug called SAR442970 in 86 adults with moderate to severe hidradenitis suppurativa, a chronic skin condition causing painful lumps. The drug is a Nanobody that targets two inflammatory proteins. Researchers compared it to a placebo to see if it co…

This Phase 3 trial tested whether the oral drug tolebrutinib can delay disability progression in people with primary progressive multiple sclerosis (PPMS). 767 adults with PPMS received either tolebrutinib or a placebo. The study measured time to confirmed disability worsening ov…

This study tested whether a drug called caplacizumab, combined with immune-suppressing medicines, could treat a rare blood clotting disorder called immune-mediated thrombotic thrombocytopenic purpura (iTTP) without the usual plasma exchange procedure. Fifty-one adults aged 18 to …

This study tested the drug dupilumab in 62 people with allergic fungal rhinosinusitis, a condition where fungus causes severe sinus inflammation. Participants received either dupilumab or a placebo injection for 52 weeks. The main goal was to see if dupilumab could reduce sinus b…

This study tested the drug dupilumab (Dupixent) in 15 children aged 2 to 12 who have chronic spontaneous urticaria (CSU), also known as long-lasting hives, that didn't get better with antihistamines. The main goals were to check how the drug behaves in the body and to see if it's…

This study followed 378 children with asthma who had already taken dupilumab in an earlier trial. Researchers wanted to see if the drug is safe and tolerable over a full year. They also measured how well it controls asthma symptoms. The goal was to make sure long-term use is safe…

This study tested a new oral medication, SAR441566, in 221 adults with moderate to severe plaque psoriasis. Participants received either the drug or a placebo for 12 weeks. The main goal was to see if the drug could reduce psoriasis severity by at least 75%. Results will help det…

This study tested the long-term safety of the drug SAR442168 in 125 people with relapsing multiple sclerosis who had already completed a previous study. Researchers monitored side effects and checked brain scans for disease activity over about 4.5 years. The goal was to see if th…

This study tested whether giving Fabrazyme, a lifelong enzyme replacement therapy for Fabry disease, at a faster infusion rate is safe and tolerable. Eight patients who had been on Fabrazyme without recent reactions participated. The goal was to see if shortening infusion time co…

This completed phase 4 trial directly compared two injectable drugs, dupilumab (Dupixent) and omalizumab (Xolair), in 360 adults with severe chronic rhinosinusitis with nasal polyps and asthma. The main goals were to see which drug better reduced polyp size and improved sense of …

This Phase 2 study tested an experimental drug called SAR441344 in 84 adults with primary Sjögren's syndrome, a condition causing dry eyes, dry mouth, and fatigue. Participants received either the drug or a placebo by injection over 12 weeks. The goal was to see if the drug could…

This study tested two daily doses (150mg vs 300mg) of the drug vandetanib in 81 adults with advanced medullary thyroid cancer that had spread or caused symptoms. The goal was to see which dose better shrinks tumors and how side effects compare. Patients took the drug for up to 24…

This study tested the drug dupilumab in 63 Chinese adults with chronic sinusitis and nasal polyps. Participants received either dupilumab injections or a placebo, plus a standard nasal steroid spray, for 24 weeks. The main goal was to see if dupilumab could shrink nasal polyps an…

This study tested a new drug called SAR444245 combined with other cancer treatments in 138 adults with advanced gastrointestinal cancers, including esophageal, stomach, liver, and colorectal cancer. The goal was to see if the combination could shrink tumors. The study is complete…

This phase 3 study tested the drug sarilumab (Kevzara®) in 420 adults hospitalized with severe or critical COVID-19. Participants received either sarilumab or a placebo by IV. The main goal was to see if sarilumab speeds up clinical improvement. The trial also tracked survival, n…

This study tested two injectable diabetes drugs in 582 Chinese adults whose blood sugar was not well controlled with oral medications. One group received iGlarLixi (a mix of insulin and another drug), and the other received IDegAsp (a different insulin mix). The main goal was to …

This study looked at how a common gene mutation (ABCG2) affects the levels and side effects of the MS drug teriflunomide in 82 Chinese patients. Participants took teriflunomide 14 mg daily for 24 weeks. The goal was to see if the mutation changes drug exposure and safety, which c…

This study tested a long-acting insulin called insulin glargine U300 in 570 Chinese adults with type 2 diabetes whose blood sugar was not well controlled. Some participants had never used insulin before, while others switched from another basal insulin. The main goal was to see h…

This study tested a combination of two drugs, plerixafor and G-CSF, to help collect stem cells from the blood of 53 people with multiple myeloma. The goal was to see if this approach could gather enough healthy stem cells for a transplant in fewer sessions. Results showed the com…

This Phase 3 trial tested whether a single pill combining ezetimibe and rosuvastatin works better than rosuvastatin alone for lowering LDL (bad) cholesterol. The study included 305 Chinese adults whose cholesterol was not well controlled on statin therapy. Participants took eithe…

This study tested a drug called caplacizumab in 21 Japanese adults with acquired thrombotic thrombocytopenic purpura (aTTP), a rare condition causing dangerous blood clots. Participants received caplacizumab alongside standard treatments like plasma exchange and steroids. The goa…

This early-stage trial tested an oral drug called SAR443122 in 68 hospitalized adults with severe COVID-19. The goal was to see if the drug could safely reduce harmful inflammation, measured by a blood marker called CRP. Participants were randomly assigned to receive the drug or …

This study tested a long-acting insulin called glargine (brand name Toujeo) in 228 adults with type 2 diabetes whose blood sugar was still too high despite taking oral diabetes medications. The main goal was to see how safe the insulin was, including any low blood sugar episodes.…

This study tested whether dupilumab, an injected drug for eczema, improves skin barrier function in 52 people with moderate to severe atopic dermatitis. Researchers measured water loss from the skin after tape stripping to assess barrier repair over 16 weeks. The goal was to see …

This study tested the drug dupilumab in 151 adults with prurigo nodularis, a condition causing intense itching and raised skin bumps. Participants had severe itch that creams could not control. They received either dupilumab injections or a placebo for 24 weeks. The main goal was…

This phase 2b trial tested an experimental oral drug called SAR442168 in 130 adults with relapsing multiple sclerosis. The goal was to find the best dose to reduce new active brain lesions seen on MRI scans. Participants took the drug or a placebo for 12 to 16 weeks, and research…

This early study tested a new clotting factor called efanesoctocog alfa (BIVV001) in 13 adults with severe hemophilia A. The goal was to see how long it stays in the body compared to standard and extended half-life factors. Participants received single injections of each type in …

This early-stage study tested a new oral drug called SAR441566 in 10 healthy Japanese men to see how safe it is and how the body processes it. The drug is being developed for rheumatoid arthritis, an autoimmune disease that causes joint pain and swelling. The study only looked at…

This study tested the drug dupilumab in 160 adults with prurigo nodularis, a skin condition causing intense itching and bumps. Participants received either dupilumab injections or a placebo for up to 24 weeks. The main goal was to see if dupilumab could reduce itch by at least 4 …

This study looked at how dupilumab, an injectable biologic drug, affects the skin barrier in 41 children aged 6 to 12 with moderate to severe atopic dermatitis (eczema). Researchers measured water loss through the skin after removing thin layers with tape to assess barrier functi…

This study gave sutimlimab to 7 adults in Japan with cold agglutinin disease (CAD) who had already completed earlier trials and still needed treatment. The goal was to monitor safety and side effects over time until the drug became commercially available. It is a small, open-labe…

This study tested the enzyme replacement drug imiglucerase (Cerezyme) in 12 Chinese patients with Gaucher disease type 3, a rare genetic disorder that affects the brain and body. Participants received the highest approved dose (60 units per kilogram) every two weeks for one year.…

This study tested the drug dupilumab (Dupixent) in 44 Chinese patients aged 12 to 65 with moderate to severe atopic dermatitis (eczema). The goal was to see if the drug improves skin barrier function by measuring water loss through the skin over 16 weeks. Participants received du…

This early-stage trial tested an experimental drug called SAR442085 in 37 people with multiple myeloma that had returned or stopped responding to prior treatments. The main goals were to find a safe dose and check for any signs that the drug shrinks tumors. Participants received …

This study tested a drug combination (isatuximab, pomalidomide, and dexamethasone) in 56 patients with multiple myeloma that had returned or stopped responding to prior treatments. The main goal was to see if giving isatuximab as a shot under the skin works as well as giving it t…

This study tested the drug dupilumab in 25 adults with chronic sinusitis and nasal polyps that weren't helped by other treatments. Participants received injections for up to 52 weeks. The main goal was to see if polyp size decreased by at least 1 point on a standard scale after 2…

This study tested dupilumab, an injectable drug, in 82 people with cold urticaria (hives triggered by cold) who still had symptoms despite taking antihistamines. The goal was to see if dupilumab could prevent hives after an ice cube test and improve quality of life. Participants …

This study tested the drug dupilumab (given as a shot) plus steroid creams in 62 Japanese children aged 6 months to 18 years with moderate-to-severe eczema that wasn't controlled by other treatments. The goal was to see if dupilumab could improve skin symptoms and itching over 16…

This large Phase 3 trial tested whether adding aflibercept (a drug that blocks blood vessel growth) to standard chemotherapy (docetaxel) could help people with advanced non-small cell lung cancer live longer. Over 900 participants who had already tried one platinum-based treatmen…

This completed Phase 4 study tested Soliqua 100/33, a once-daily injectable combining insulin and a GLP-1 drug, in 124 adults with very uncontrolled type 2 diabetes (HbA1c ≥9%) who were not yet on insulin. The goal was to see if the drug increased the time their blood sugar staye…

This study tested dupilumab (Dupixent) in 109 adults with uncontrolled moderate-to-severe asthma. Researchers used lung scans and breathing tests to see if the drug reduces airway inflammation and mucus plugging. Participants received either dupilumab or a placebo for 24 weeks. T…

This study tested an experimental drug called lunsekimig in 150 adults with moderate-to-severe atopic dermatitis (eczema). Participants received one of three doses of the drug or a placebo as a shot under the skin for 24 weeks. The main goal was to see if the drug reduces eczema …

This completed phase 3 trial tested whether a patient outreach program—regular phone calls every two weeks—could help people with advanced medullary thyroid cancer spend less time experiencing moderate-to-severe side effects from the drug vandetanib. The study enrolled 205 adults…

This study tested the safety and effectiveness of Allegra D (fexofenadine plus pseudoephedrine) in 203 people aged 12 and older with allergic rhinitis. Participants took the medication for up to 13 days, and researchers tracked side effects and symptom improvement using nasal and…

This early-stage study tested a single injection of a new drug (SAR446959) into the knee joint of 32 adults aged 45-65 with knee osteoarthritis. The main goal was to check safety and how the drug moves in the body, not to prove it works. Participants were monitored for about 6 mo…

This study followed 112 adults with severe asthma who were starting treatment with dupilumab (Dupixent). Researchers measured changes in quality of life using a standard questionnaire at 12, 24, and 52 weeks. The goal was to see if the drug helps people feel better and breathe ea…

This early-stage trial tested a new oral drug called SAR441566 in 38 adults with mild to moderate psoriasis. Participants took the drug or a placebo twice daily for 4 weeks. The main goal was to check safety and tolerability, while also looking at changes in skin lesion severity.…

This study tested whether dupilumab, an injectable drug that reduces inflammation, can improve sleep quality in adults with moderate-to-severe atopic dermatitis (eczema). 188 participants received either dupilumab or a placebo. The main goal was to measure changes in sleep qualit…

This early-stage trial tested the safety and tolerability of a new drug called SAR443765 in 36 people, including healthy volunteers and those with mild-to-moderate asthma. Participants received either the drug or a placebo, and researchers monitored for side effects and how the d…

This study tested a special patch that gives off infrared heat to treat mild to moderate acute low back pain. 221 adults with back pain for less than a month wore the patch. Researchers measured how many people felt at least 30% less pain after 5 days without needing extra painki…

This study will observe how many eligible infants in Czechia receive nirsevimab, a monoclonal antibody that helps prevent RSV, during their first RSV season. Researchers will survey parents of about 250 infants born between April 2025 and March 2027 to understand immunization rat…

This study looked at how well vaccines work in adults with moderate-to-severe eczema who are taking amlitelimab, an experimental drug. About 224 participants received either amlitelimab or a placebo along with tetanus and pneumonia vaccines. The goal was to see if the drug change…

This study follows 376 people aged 12 and older who are starting Dupixent for asthma in real-world clinics. Researchers will track their medical history, how they use the drug, and whether it improves lung function and reduces attacks. No new treatment is given—the goal is to lea…

This study looks at two medicines, alirocumab and inclisiran, that help lower bad cholesterol (LDL-C) in people with heart disease. Researchers will use real-world data from about 124 patients to see which drug reduces cholesterol more over time. The goal is to understand how the…

This study looks at children with eczema (atopic dermatitis) that is not well controlled by prescription creams or for whom such creams are not advised. Researchers are collecting blood and cheek swab samples to find biological markers (biomarkers) that may be linked to how the d…

This completed Phase 1 study tested whether a single dose of balinatunfib affects the heart's electrical activity in 48 healthy adults aged 18 to 55. Participants received balinatunfib, a placebo, and an active control (moxifloxacin) in a crossover design. The main goal was to me…

This completed study observed over 4,500 adults with atherosclerotic cardiovascular disease who had never had a heart attack or stroke. Researchers compared those taking alirocumab (a cholesterol-lowering drug) to those not on similar therapy, using real-world data to see if the …

This study looked at whether healthcare professionals in Saudi Arabia are aware of and follow safety measures for the drug leflunomide, used for rheumatoid and psoriatic arthritis. Researchers surveyed 302 doctors and pharmacists to see if they received and read safety materials,…

This study looked at health insurance records of over 81,000 people aged 14 to 44 in Germany to see how often chlamydia leads to serious health problems like infertility or pelvic disease, and how much it costs the healthcare system. Researchers tracked infections, complications,…

This completed study looked at whether healthcare professionals in Saudi Arabia received and understood safety materials about the epilepsy drug Depakine (sodium valproate). Researchers surveyed 455 doctors, pharmacists, and gynecologists to measure their knowledge and behavior. …

This study looked at how a new drug called amlitelimab affects the way the body processes other medications in adults with moderate-to-severe atopic dermatitis (eczema). 23 participants received amlitelimab and a cocktail of common drugs to measure changes in drug levels. The goa…

This early-stage study tested two different injection devices for delivering the drug amlitelimab under the skin. It involved 212 healthy adults aged 18 to 55. The goal was to see if the devices deliver the same amount of drug and are safe, not to treat any disease.

This study looked at how adults aged 18 and older experienced a trivalent recombinant influenza vaccine. Over 1,000 participants completed a short online survey about their injection experience, side effects, and willingness to get vaccinated again. The goal was to better underst…

This study looked at how itepekimab, an experimental drug, affects airway inflammation in 49 adults aged 40-70 with COPD who smoke or used to smoke. Participants stayed on their usual COPD medications while receiving itepekimab for 12 weeks. The goal was to understand the drug's …

This study looked at how chronic immune thrombocytopenia (ITP) affects thinking skills and fatigue in adults. Researchers measured brain function and inflammation using blood tests and questionnaires in 97 patients. The goal was to better understand these connections, not to test…

This early-stage study gave a single dose of a radioactive-labeled version of the experimental breast cancer drug amcenestrant to 6 healthy postmenopausal women. The goal was to track how the drug is absorbed, broken down, and eliminated from the body. The results will help guide…

This study compares two versions of insulin lispro—one standard strength and one double-strength—to see if they work the same in the body. About 90 adults with type 1 diabetes will receive a single dose of each in random order. The goal is to check if the stronger formula is bioe…

This early-stage study gave a single oral dose of a radioactive form of the experimental drug SAR442168 to 6 healthy men. Researchers measured how much of the drug was excreted in urine and stool, and how it moved through the bloodstream. The goal was to understand the drug's met…

This early-stage trial tested a single dose of a new drug called SAR441255 in 48 healthy, lean to overweight adults. The main goal was to check safety and how the body processes the drug. Researchers also looked at effects on blood sugar and insulin levels. This is a first step t…

This study examined 60 children under 18 with an unexplained enlarged spleen to see how often rare diseases like Gaucher disease were the cause. Researchers ruled out common reasons first, then tested for specific enzyme deficiencies. The goal was to better understand what hidden…

This early-stage study tested two different versions of the experimental drug amlitelimab in 32 healthy adults. The goal was to see how the body absorbs and processes each version and to check for any safety issues. Participants received a single injection and were monitored for …

This completed Phase 1 study tested whether a new version of the drug dupilumab works the same in the body as the current version. 182 healthy adults aged 18-65 received a single injection of either the new or current product. The goal was to compare how the drug is absorbed, not…

This study looked at how the drug fexinidazole, used for sleeping sickness, is processed by the body in people with mild or moderate liver impairment compared to those with normal liver function. Twenty-one adults took a single 1200 mg tablet, and researchers measured drug levels…

This completed Phase 1 study tested how two common drugs—gemfibrozil (for cholesterol) and rifampicin (an antibiotic)—affect the levels of tolebrutinib, an experimental oral drug for multiple sclerosis. Thirty healthy men aged 18 to 45 took tolebrutinib alone and then with each o…

This study looked at how dupilumab, an injectable eczema drug, changes nerve fibers in the skin of 54 adults with moderate-to-severe atopic dermatitis and chronic itching. Researchers took skin biopsies to measure nerve density and branching before and after treatment. The goal w…

This early-stage trial tested the safety and tolerability of a new drug called SAR441344 in 56 healthy adults. Participants received either the drug or a placebo by injection or infusion. The study did not aim to treat any disease, but to gather initial safety data.

This study tested whether the experimental drug SAR441566, being developed for rheumatoid arthritis, makes skin more sensitive to ultraviolet (UV) light. Sixty healthy adults aged 18 to 55 received either the drug, a placebo, or ciprofloxacin (a known sun-sensitizer). Researchers…

This early-phase study tested a new investigational drug called SAR444336 in 76 healthy adults to see if it is safe and how the body processes it. Participants received either the drug or a placebo as a single or repeated injection. The goal was to gather safety data before movin…

This early-stage study looked at how a single dose of venglustat is processed in people with mild, moderate, or severe liver problems compared to healthy adults. Twenty-six participants received one tablet and were monitored for about three weeks. The goal was to see if liver fun…

This early-stage study tested two different tablet forms of the drug rilzabrutinib in 28 healthy adults. The goal was to see how well each form is absorbed by the body, both with and without food. Participants took a single dose of each tablet in a random order, with a day off be…