New pneumonia vaccine shows promise in older adults

NCT ID NCT04583618

Completed ⭐️ VACCINE ⭐️ Sponsor: Sanofi Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested three new pneumococcal vaccine formulations in 750 healthy adults aged 50 to 84. The goal was to see how well they trigger an immune response and how safe they are compared to two existing vaccines. Participants received a single shot, and researchers measured antibody levels and tracked side effects for one month.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Pneumococcal conjugate vaccine (SP0202 formulations)
What this could lead to: If successful, this could lead to a new vaccine option that protects older adults against pneumococcal disease, potentially offering broader or stronger immunity than current vaccines.
What could go wrong: This is a Phase 2 trial, so results are preliminary. The new vaccine may not prove more effective or safer than existing ones in larger Phase 3 studies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

pneumococcal infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PNEUMOCOCCAL IMMUNIZATION

Contacts and locations

Locations

Advanced Clinical Research - Magic View Site Number : 8400003

Meridian, Idaho, 83642, United States
Aventiv Research Columbus Site Number : 8400007

Columbus, Ohio, 43213, United States
Be Well Clinical Studies Site Number : 8400018

Lincoln, Nebraska, 68516, United States
Biotrial Inc Site Number : 8400006

Newark, New Jersey, 07103, United States
Coastal Carolina Research Center - N Charleston Site Number : 8400004

North Charleston, South Carolina, 29405, United States
Emmaus Research Center, Inc Site Number : 8400014

Anaheim, California, 92804, United States
JBR Clinical Research Site Number : 8400008

Salt Lake City, Utah, 84107, United States
Jacksonville Center for Clinical Research Site Number : 8400016

Jacksonville, Florida, 32216, United States
Paradigm Clinical Research Center Wheat Ridge Site Number : 8400002

Wheat Ridge, Colorado, 80033, United States
Peninsula Research Associates Site Number : 8400012

Rolling Hills Estates, California, 90274, United States
Plains Clinical Research Center, LLC Site Number : 8400011

Fargo, North Dakota, 58104, United States
Preferred Primary Care Physicians Site Number : 8400009

Pittsburgh, Pennsylvania, 15236, United States
Suncoast Research Associates, LLC Site Number : 8400017

Miami, Florida, 33173, United States
Velocity Clinical Research Site Number : 8400005

Metairie, Louisiana, 70006, United States
Velocity Clinical Research Valparaiso Site Number : 8400001

Valparaiso, Indiana, 46383, United States
Velocity Clinical Research, Medford Site Number : 8400010

Medford, Oregon, 97504, United States
WR-CRCN, LLC Site Number : 8400013

Las Vegas, Nevada, 89106, United States

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