Liver function may change how venglustat works in the body
NCT ID NCT05718258
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This early-stage study looked at how a single dose of venglustat is processed in people with mild, moderate, or severe liver problems compared to healthy adults. Twenty-six participants received one tablet and were monitored for about three weeks. The goal was to see if liver function affects drug levels and safety, not to treat any disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
venglustat
What this could lead to
If successful, this study could help doctors understand how to safely dose venglustat in patients with liver problems.
What could go wrong
This is an early, small study focused on drug processing, not treatment effects. Results may not apply to long-term use or other populations.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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American Research Corporation Site Number : 8400005
San Antonio, Texas, 78215, United States
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Clinical Pharmacology of Miami Site Number : 8400002
Miami, Florida, 33014, United States
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Inland Empire Liver Foundation Site Number : 8400004
Rialto, California, 92377, United States
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Investigational Site Number : 2760001
Kiel, 24105, Germany
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Nucleus Network Site Number : 8400001
Saint Paul, Minnesota, 55114, United States
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Volunteer Research Group-NOCCR Site Number : 8400003
Knoxville, Tennessee, 37920, United States