New hope for Hard-to-Treat multiple myeloma: first human trial of SAR442085
NCT ID NCT04000282
First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 27 times
Summary
This early-stage study tested a new drug called SAR442085 in 37 adults with multiple myeloma that had returned or stopped responding to prior treatments. The main goals were to find the safest dose and check for any signs that the drug shrinks tumors. Researchers also monitored side effects and how the drug moves through the body.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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City of Hope Site Number : 8400002
Duarte, California, 91010, United States
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Dana Farber Cancer Institute Site Number : 8400003
Boston, Massachusetts, 02115, United States
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Froedtert Hospital & Medical College of Wisconsin Site Number : 8400004
Milwaukee, Wisconsin, 53226, United States
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Investigational Site Number : 1580001
Taipei, 10002, Taiwan
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Investigational Site Number : 2030001
Prague, 12808, Czechia
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Investigational Site Number : 2030002
Brno, 62500, Czechia
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Investigational Site Number : 2030003
Ostrava - Poruba, 70852, Czechia
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Investigational Site Number : 2500001
Toulouse, 31059, France
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Investigational Site Number : 3000001
Athens, 11528, Greece
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Investigational Site Number : 7240001
Salamanca, Salamanca, 37007, Spain
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Mayo Clinic of Rochester Site Number : 8400005
Rochester, Minnesota, 55905, United States
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UNC Chapel Hill Site Number : 8400006
Chapel Hill, North Carolina, 27599, United States
Conditions
Explore the condition pages connected to this study.