PLASMA CELL MYELOMA

This study tests whether a combination of three drugs—belantamab, pomalidomide, and dexamethasone—can help control high-risk myeloma after a stem cell transplant. About 34 participants who have already had a transplant and achieved at least a partial response will receive this th…

This study compares a four-drug combination (daratumumab, bortezomib, lenalidomide, and dexamethasone) against a three-drug combination (daratumumab, lenalidomide, and dexamethasone) in people newly diagnosed with multiple myeloma who are not eligible for early stem cell transpla…

This early-stage study tests a new radioactive tracer called [89Zr]DFO-YS5 for PET scans to find multiple myeloma cells that have a specific protein (CD46). About 20 adults with confirmed multiple myeloma will receive the tracer and have a PET scan. The goal is to see if this met…

This study tests whether loratadine, a common allergy medicine, can reduce bone pain caused by the drug G-CSF in people with multiple myeloma. About 70 participants will receive loratadine or a placebo during stem cell collection. The goal is to see if this simple, low-cost appro…

This study looks at whether non-chemo approaches like physical activity, intermittent fasting, or the beta-blocker propranolol can improve immune function and quality of life in people with multiple myeloma or related blood disorders. Researchers will measure changes in immune ce…

This study tracks memory and thinking changes in 100 adults with blood cancers who receive whole brain radiation. Researchers will test cognitive skills like recall and attention over time. The goal is to better understand the mental side effects of this treatment, not to change …