New drug shows promise for nasal polyps in chinese patients

NCT ID NCT05878093

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested the drug dupilumab in 63 Chinese adults with chronic sinusitis and nasal polyps. Participants received either dupilumab injections or a placebo, plus a standard nasal steroid spray, for 24 weeks. The main goal was to see if dupilumab could shrink nasal polyps and improve congestion.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Dupilumab (injectable drug) plus budesonide nasal spray

What this could lead to

If successful, this could provide a new treatment option for Chinese adults with nasal polyps that reduces polyp size and eases congestion.

What could go wrong

This is a small Phase 3 trial (63 participants) and results may not apply to all patients. Dupilumab can cause injection site reactions and allergic reactions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Investigational Site Number : 1560001

    Beijing, 100730, China

  • Investigational Site Number : 1560004

    Hangzhou, 310003, China

  • Investigational Site Number : 1560005

    Beijing, 100044, China

  • Investigational Site Number : 1560006

    Hefei, 230001, China

  • Investigational Site Number : 1560007

    Wuhan, 430022, China

  • Investigational Site Number : 1560009

    Yantai, 264000, China

  • Investigational Site Number : 1560010

    Chengdu, 610041, China

  • Investigational Site Number : 1560011

    Guangzhou, China

  • Investigational Site Number : 1560012

    Guangzhou, 510163, China

  • Investigational Site Number : 1560013

    Qingdao, China

  • Investigational Site Number : 1560014

    Chongqing, 400016, China

  • Investigational Site Number : 1560016

    Jinan, 250102, China

  • Investigational Site Number : 1560017

    Shanghai, 200065, China

  • Investigational Site Number : 1560018

    Taiyuan, 030001, China

  • Investigational Site Number : 1560020

    Zibo, 255036, China

  • Investigational Site Number : 1560021

    Wuhan, 430060, China

  • Investigational Site Number : 1560022

    Fuzhou, 350005, China

  • Investigational Site Number : 1560025

    Jingzhou, 434020, China