New asthma drug passes first safety hurdle in small trial

NCT ID NCT05366764

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-stage trial tested the safety and tolerability of a new drug called SAR443765 in 36 people, including healthy volunteers and those with mild-to-moderate asthma. Participants received either the drug or a placebo, and researchers monitored for side effects and how the drug moved through the body. The goal was to see if the drug is safe enough for further testing, not to measure its effectiveness against asthma.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SAR443765 (an injectable drug)

What this could lead to

If successful, this could point toward a new treatment option for asthma that helps control symptoms.

What could go wrong

This is a very early Phase 1 trial with only 36 participants, focused on safety, not effectiveness. The drug may not work or could have side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Investigational Site Number : 2760001

    Berlin, Germany

  • Investigational Site Number : 8260001

    Belfast, BT9 6AD, United Kingdom