Needle vs. IV: new shot for tough myeloma shows promise

NCT ID NCT04045795

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 26 times

Summary

This study tested a cancer drug called isatuximab given either as a shot under the skin or through an IV, along with two other medicines (pomalidomide and dexamethasone), in 56 adults with multiple myeloma that had returned or stopped responding to prior treatments. The main goals were to check safety, how the body processes the drug, and whether the shot form works as well as the IV form. This is a disease-control study, meaning it aims to manage the cancer rather than cure it.

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Contacts and locations

Locations

  • City of Hope Site Number : 8400002

    Duarte, California, 91010, United States

  • Gabrail Cancer Center Site Number : 8400001

    Canton, Ohio, 44718, United States

  • Investigational Site Number : 0360001

    Wollongong, New South Wales, 2500, Australia

  • Investigational Site Number : 0360002

    Blacktown, New South Wales, 2148, Australia

  • Investigational Site Number : 0360003

    Richmond, Victoria, 3121, Australia

  • Investigational Site Number : 0360004

    Fitzroy, Victoria, 3065, Australia

  • Investigational Site Number : 0560001

    Leuven, 3000, Belgium

  • Investigational Site Number : 2500001

    Nantes, 44093, France

  • Investigational Site Number : 2500002

    Toulouse, 31059, France

  • Investigational Site Number : 3920001

    Shibuya-ku, Tokyo, 150-8935, Japan

  • Investigational Site Number : 3920002

    Okayama, Okayama-ken, 701-1192, Japan

  • Investigational Site Number : 7240001

    Badalona, Catalunya [Cataluña], 08916, Spain

  • Investigational Site Number : 7240002

    Santander, Cantabria, 39008, Spain

  • ~Banner MD Anderson Cancer Center Site Number : 8400005

    Gilbert, Arizona, 85234, United States

Conditions

Explore the condition pages connected to this study.