New shot could shrink nasal polyps and ease breathing
NCT ID NCT06454240
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a drug called lunsekimig in adults with chronic sinusitis and nasal polyps that persist despite using steroid sprays. The drug is given as a shot under the skin every few weeks. Researchers will measure changes in polyp size and nasal congestion over 24 weeks. The trial includes 79 participants and is already completed.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
lunsekimig (a drug given as a shot under the skin)
What this could lead to
If it works, this could lead to a new treatment option for people with nasal polyps that are not well controlled with standard sprays.
What could go wrong
This is an early Phase 2 study with only 79 participants, so results may not apply to everyone. The drug may not work better than placebo, and side effects are still being studied.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Advanced Research Institute - Odgen- Site Number : 8400022
Ogden, Utah, 84405, United States
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Alamo ENT Associates Site Number : 8400001
San Antonio, Texas, 78258, United States
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Allergy & Rheumatology- Site Number : 8400005
La Jolla, California, 92037, United States
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Berkson Medical - McKinney- Site Number : 8400014
McKinney, Texas, 75070, United States
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Eastern Virginia Medical School (EVMS) Medical Group- Site Number : 8400008
Norfolk, Virginia, 23510, United States
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Emory University Hospital Midtown- Site Number : 8400012
Atlanta, Georgia, 30308, United States
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Essential Medical Research- Site Number : 8400020
Tulsa, Oklahoma, 74137, United States
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Gary Gross Pharmaceutical Research & Consulting, Inc. Site Number : 8400004
Dallas, Texas, 75231, United States
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Harvard Medical School - Brigham and Women's Hospital Site Number : 8400016
Boston, Massachusetts, 02115, United States
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Investigational Site Number : 0320001
Buenos Aires, 1121, Argentina
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Investigational Site Number : 0320002
Rosario, Santa Fe Province, 2000, Argentina
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Investigational Site Number : 0320003
Mendoza, 5500, Argentina
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Investigational Site Number : 0560001
Leuven, 3000, Belgium
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Investigational Site Number : 0560002
Ghent, 9000, Belgium
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Investigational Site Number : 1000001
Sofia, 1612, Bulgaria
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Investigational Site Number : 6160001
Warsaw, Masovian Voivodeship, 00-909, Poland
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Investigational Site Number : 6160002
Krakow, Lesser Poland Voivodeship, 31-033, Poland
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Investigational Site Number : 6160003
Katowice, Silesian Voivodeship, 40-611, Poland
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Investigational Site Number : 6160004
Poznan, 60-693, Poland
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Investigational Site Number : 6160005
Warsaw, Masovian Voivodeship, 02-507, Poland
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Investigational Site Number : 6160007
Wroclaw, 53-034, Poland
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Investigational Site Number : 8260001
Newcastle upon Tyne, NE7 7DN, United Kingdom
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Investigational Site Number : 8260003
Manchester, M13 9WL, United Kingdom
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Investigational Site Number : 8260004
Gloucester, Gloucestershire, GL1 3NN, United Kingdom
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James A Haley Veterans' Hospital- Site Number : 8400015
Tampa, Florida, 33612, United States
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McGovern Medical School - UT Physicians Dermatology - Bellaire Station- Site Number : 8400017
Bellaire, Texas, 77401, United States
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Sacramento Ear Nose & Throat - Roseville- Site Number : 8400003
Roseville, California, 95661, United States
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Senta Clinic- Site Number : 8400025
San Diego, California, 92018, United States
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The Allergy Group - Asthma & Allergy Boise- Site Number : 8400002
Boise, Idaho, 83706, United States