New hope for kids with stubborn hives: dupilumab studied

NCT ID NCT05526521

First seen Nov 19, 2025 · Last updated May 13, 2026 · Updated 27 times

Summary

This study tested the safety and drug levels of dupilumab in 15 children aged 2 to 12 with chronic spontaneous urticaria (CSU), also known as long-lasting hives, that did not get better with standard antihistamines. The children received dupilumab for 24 weeks and were monitored for side effects and how the drug moved through their bodies. The goal was to see if this treatment could help control their symptoms.

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Contacts and locations

Locations

  • Boston Childrens Health Physicians Site Number : 8400017

    Hawthorne, New York, 10532, United States

  • Childrens Hospital Medical Center of Akron- Site Number : 8400020

    Akron, Ohio, 44308, United States

  • Cincinnati Children's Hospital Medical Center - PIN- Site Number : 8400001

    Cincinnati, Ohio, 45229-3026, United States

  • Columbia University Irving Medical Center Site Number : 8400003

    New York, New York, 10032, United States

  • Investigational Site Number : 1240001

    Montreal, Quebec, H4A 3J1, Canada

  • Investigational Site Number : 1240007

    Hamilton, Ontario, L8S1G5, Canada

  • Investigational Site Number : 1240009

    Calgary, Alberta, T2W 4X9, Canada

  • Investigational Site Number : 1240010

    Edmonton, Alberta, T5J 3S9, Canada

  • Investigational Site Number : 3920001

    Yokohama, Kanagawa, 232-8555, Japan

  • Investigational Site Number : 3920002

    Tsu, Mie-ken, 514-0125, Japan

  • Monroe Carell Jr. Childrens Hospital at Vanderbilt- Site Number : 8400005

    Nashville, Tennessee, 37232, United States

  • Pediatric Dermatology of Miami Site Number : 8400015

    Coral Gables, Florida, 33146, United States

  • Treasure Valley Medical Research Site Number : 8400019

    Boise, Idaho, 83706, United States

  • Vital Prospects Clinical Research Institute, P.C.- Site Number : 8400002

    Tulsa, Oklahoma, 74136, United States

  • Washington University School of Medicine- Site Number : 8400004

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.