New clotting factor could mean fewer shots for hemophilia a

NCT ID NCT05042440

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early study tested a new clotting factor called efanesoctocog alfa (BIVV001) in 13 adults with severe hemophilia A. The goal was to see how long it stays in the body compared to standard and extended half-life factors. Participants received single injections of each type in a fixed order. The study is complete and focused on safety and drug levels, not on preventing bleeds.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Efanesoctocog alfa (BIVV001), a longer-lasting clotting factor

What this could lead to

If it works, this could mean fewer injections for people with hemophilia A, making treatment easier.

What could go wrong

This is a very early, small study (13 people) only looking at how the drug moves in the body, not whether it prevents bleeding. It may not work better than existing treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hemophilia A severe hemophilia A

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Investigational Site Number :1000001

    Sofia, 1756, Bulgaria