Ain Shams University

This study tests a shorter, more intense radiation schedule combined with chemotherapy for cervical cancer. The goal is to see if this approach works as well or better than standard treatment, while reducing overall treatment time. About 30 adults with stage II or III cervical ca…

This study tests whether N-acetyl cysteine (NAC), a safe supplement, can reduce oxidative stress and improve eye health in people with type 2 diabetes who have mild to moderate diabetic retinopathy. About 76 adults aged 18-70 will take NAC to see if it lowers damage to blood vess…

This study compares two surgical methods to correct large-angle exotropia, a condition where one eye turns outward. Researchers will test muscle transplantation versus a Y-splitting technique in 30 people aged 6 and older. The goal is to see which method better aligns the eyes an…

This study compares two surgical techniques to repair large macular holes, a condition that blurs central vision. About 20 people with a full-thickness macular hole will receive either a Tenon capsule graft or an internal limiting membrane (ILM) flap during vitrectomy. The goal i…

This study tests if the heart drug nebivolol can protect the hearts of women with HER2-positive breast cancer who are receiving trastuzumab, a treatment that can weaken the heart. Researchers will measure heart function and quality of life in 56 participants over several months. …

This study tests a systematic approach to treat orbital lymphatic malformation in children and teens. Participants receive either injection sclerotherapy, the drug sirolimus, or both, depending on their condition. The goal is to see if sirolimus is safe and effective at shrinking…

This study compares two modern, less invasive surgeries for removing kidney stones that are 2-3 cm in size. About 120 adults will be randomly assigned to get either mini-percutaneous nephrolithotomy (Mini-PCNL) or flexible ureteroscopy with a special suction tube. The main goal i…

This study tests a new 3D printed aligner for infants born with a complete cleft lip and palate. The device aims to make nasoalveolar molding treatment more accurate and easier to use. Twenty infants under 45 days old will receive the treatment, and doctors will measure how much …

This study compares two methods to lift the sinus floor before placing dental implants in the upper jaw. Twenty adults with missing back teeth will receive either a newer rotating tool or a traditional tapping method. The goal is to see which approach gives better bone growth and…

This study tests whether a manuka honey mouthwash can improve gum disease in people with kidney failure who are on dialysis. Gum disease is very common in these patients and can lead to tooth loss and inflammation. Researchers will measure gum attachment, bleeding, and a marker o…

This study looks at whether giving vitamin K2 can prevent bone loss in children with nephrotic syndrome who are on long-term steroid treatment. Steroids can weaken bones, but vitamin K2 might help keep them strong. The study will involve 60 children under 16 who have been on ster…

This study tests whether alpha lipoic acid, a common antioxidant supplement, can prevent or reduce skin irritation caused by radiation therapy in breast cancer patients. Researchers will enroll 40 women with early-stage breast cancer who are scheduled for radiation. The goal is t…

This study compares two ultrasound-guided nerve block techniques for distal upper limb surgery to see which one numbs the arm faster. Fifty adults having arm or hand surgery will be randomly assigned to receive one of the two blocks. The goal is to improve patient comfort and spe…

This study compares two ultrasound-guided nerve blocks (M-TAPA and quadratus lumborum) for pain control after laparoscopic gallbladder removal. 52 adults undergoing this surgery will receive one of the two blocks, and researchers will measure how long it takes before they need ex…

This study tests two treatments for white spots on front teeth that often appear after braces. It involves 18 people aged 15 to 25. Each person gets both treatments—one on each side of the mouth—to see which works better at improving tooth color and reducing spot size. Results wi…

This study tests whether a lidocaine nasal spray can reduce pain and the need for strong opioid drugs during partial turbinectomy (nose) surgery. About 50 adults having this surgery will receive either the spray or a placebo. The goal is to see if the spray helps patients recover…

This study compares two pain control methods after hip surgery: a fascia iliaca block (an injection near the hip) and intrathecal nalbuphine (a painkiller given in the spine). The goal is to see which one delays the need for extra pain medicine. The trial will include 120 adults …

This study compares three different single-use flexible ureteroscopes used to remove kidney stones. Researchers will look at which scope is most cost-effective, how long surgery takes, and how many stones are completely removed. The trial involves 180 adults aged 18 to 60 with ki…

This study tests whether a 10-week resilience training program can help nursing students better manage stress. About 90 students will either take the program during the semester or wait until after. Researchers will compare stress and resilience scores using questionnaires before…

This study tests whether itopride, a drug that helps the stomach empty faster, can reduce the risk of food or liquid staying in the stomach after 8 hours of fasting in people taking semaglutide. About 60 diabetic patients scheduled for hysterectomy will be randomly assigned to re…

This study compares two laparoscopic surgeries for apical prolapse (when the top of the vagina or uterus drops). The standard surgery (sacrocolpopexy) works well but has risks. The newer technique (pectopexy) uses a different ligament and may be safer and quicker. Researchers wil…

This study tests whether a combination of dormicum and ketamine works better than dexmedetomidine at preventing confusion (emergence delirium) in children aged 3 to 16 after deep sedation for burn-related procedures. The study will enroll 60 children and measure confusion levels …

This study tests two different methods to re-inflate the lungs after weight-loss surgery. About 100 adults having laparoscopic bariatric surgery will receive one of two breathing techniques right before waking up from anesthesia. The goal is to see which method improves oxygen le…

This study compares how quickly people can bite and chew with lower dentures held in place by two regular-sized implants versus four smaller mini-implants. Researchers will measure the time it takes for teeth to meet and separate during chewing. The goal is to see if mini-implant…

This study tests two medicines, hydrocortisone and dexmedetomidine, to see which works better at preventing shivering after abdominal surgery with general anesthesia. About 70 adults having abdominal surgery will take part. The goal is to find a safe and effective way to reduce t…

This study looks at whether adding a medicine called dexmedetomidine to the standard numbing drug bupivacaine can give longer and better pain relief for children after open appendix removal. About 60 children will take part. The goal is to see if this combination reduces the need…

This study compares three different root canal medications placed between visits for people needing a second root canal treatment. The goal is to see which one best reduces pain, swelling, and inflammation. Sixty adults with infected lower molars will be randomly assigned to one …

This study tests whether a combination of two drugs—tamsulosin and a lower dose of tadalafil—can reduce uncomfortable symptoms caused by a ureteric stent placed after kidney stone removal. About 140 adults who have a stent after stone surgery will receive either the standard or h…

This study compares a new injection method (transgrade) with a standard one (interlaminar) for people with chronic leg pain caused by a pinched nerve in the lower back. Eighty adults who have had pain for over 6 months and haven't gotten relief from other treatments will be enrol…

This study compares two ways of giving fentanyl (a painkiller) to preterm babies undergoing painful procedures like inserting a breathing tube or a central line. One method uses a tiny spray into the nose, the other uses an IV needle. The goal is to see if the nose spray works ju…

This study tests if high-level laser therapy can reduce painful mouth sores in children undergoing bone marrow transplants. Fourteen kids with at least moderate sores will get laser treatment on their lesions, and researchers will compare their healing and pain levels to those re…

This study tests whether two natural supplements—silymarin (from milk thistle) and a hesperidin/diosmin combination (from citrus)—can reduce pain and improve quality of life in people with fibromyalgia. About 90 adults with fibromyalgia will take one of the supplements or a place…

This study tests three ways to fix black triangles—the small gaps between teeth caused by missing gum tissue. Thirty adults will receive either a surgical gum graft, a gel injection, or a tooth-colored filling. Researchers will measure how well each method closes the gap and how …

This study compares two types of nerve blocks—erector spinae plane block and serratus anterior plane block—to see which one controls pain better after video-assisted lung surgery. About 50 adults aged 25 to 70 having lung procedures like lobectomy or pleurectomy will take part. T…

This study compares two pain-relief cocktails given during back surgery to see which works better. 72 adults having lumbosacral surgery will receive either dexmedetomidine or ketamine added to the standard numbing drug bupivacaine. The goal is to extend pain relief after surgery …

This study tests if a newer ultrasound-guided nerve block can control pain after hemorrhoid surgery as well as the standard saddle block. Fifty adults aged 18 to 65 having hemorrhoid removal will be randomly assigned to one of the two methods. Researchers will track pain scores a…

This study tests if giving ketamine before laparoscopic sleeve gastrectomy (a type of weight-loss surgery) can reduce pain after the operation. Researchers will compare how long it takes for patients to need extra pain medicine. The study involves 90 adults with a BMI between 35 …

This study tests whether using ultrasound to measure the airway is better than standard age-based formulas for choosing the correct breathing tube size in children with single ventricle heart conditions. About 60 children scheduled for heart surgery or catheterization will take p…

This study tests if adding nitrates (found in vegetables like beets) to a standard pre-surgery carbohydrate drink helps women recover faster after open gynecological surgery. The goal is to see if this combination reduces hospital stay. 90 women aged 18-60 with low surgical risk …

This study compares two procedures—water vapor therapy (Rezum) and prostatic artery embolization—to see which better relieves moderate-to-severe urinary symptoms caused by an enlarged prostate. About 30 men aged 50 and older who haven't responded to medication will be followed fo…

This study looks at 40 adults with septic shock to see which ultrasound method—heart or neck artery—better predicts whether fluids will help. Doctors often give fluids to raise blood pressure, but only half of patients respond. The goal is to find a more accurate way to decide wh…

This study looks at two types of dental expanders used to widen the upper jaw in teenagers aged 12 to 17. One is a standard metal expander, and the other is custom-made using 3D printing. The goal is to see which one works better and more precisely by using 3D X-rays and digital …

This study checks if a simple blood test (D-dimer) can help predict how serious pneumonia is and how well patients recover. Researchers will measure D-dimer levels in 50 adults admitted with pneumonia and compare them to a standard severity score. The goal is to see if high D-dim…

This study compares two ways to place dental implants: one uses a custom-made guide to drill the hole, while the other uses a screen that shows the dentist where to drill in real time. Researchers will measure how accurate each method is and how satisfied patients feel. The study…

This study looks at whether two simple blood test results can help doctors predict which children with severe burns will develop a serious lung condition called ARDS. Researchers will follow 60 children aged 1 to 12 with burns covering 20-40% of their body. No new treatments are …

This study looks at whether ultrasound can measure breathing muscle strength in critically ill patients on ventilators. The goal is to find a better way to predict who is ready to breathe without the machine. Researchers will scan the diaphragm and chest muscles of 77 adults in t…

This study uses bedside ultrasound to measure muscle loss, fat changes, and fluid buildup in critically ill pregnant and gynecological patients. Researchers will track 121 women in the ICU to see if these body changes relate to serious outcomes like death, need for a breathing ma…

This study follows 398 older adults after they leave the hospital to see if taking psychotropic medications (drugs that affect mood or thinking) is linked to a higher chance of falling. Researchers will also track whether falls lead to broken bones. The goal is to better understa…

This study tests whether a step-by-step feeding plan helps critically ill children in the pediatric ICU reach their nutrition goals faster and with fewer interruptions. About 80 children aged 1 month to 16 years will take part. The goal is to see if the plan reduces time to full …

This study looks at whether certain blood markers can help predict how well sepsis patients in the ICU will recover. Researchers will compare three different blood tests in 290 adults with sepsis. The goal is to find which test best predicts survival at 28 days. No new treatments…

This study looks at whether a simple ultrasound test before surgery can predict if a patient will have dangerously low blood pressure after receiving anesthesia for brain surgery. Researchers will measure the size and flexibility of a major vein and artery using ultrasound in 36 …

This study looks at how lung ultrasound can help find lung issues early in women who are critically ill due to pregnancy complications or gynecologic cancer. Researchers will check for different lung ultrasound patterns and see if they relate to patient outcomes like death or nee…

This study looks at how two common inhaled anesthetics, isoflurane and sevoflurane, affect oxidative stress (a type of cell damage) in 80 adults having gallbladder removal surgery. Participants will be randomly assigned to receive one of the two anesthetics, and researchers will …

This study is testing whether a simple ultrasound of the carotid artery in the neck can predict dangerous drops in blood pressure when people with chronic liver disease go under general anesthesia. About 35 adults will have their carotid artery measured before and during anesthes…

This study looks at whether a quick breathing measurement, called the Rapid Shallow Breathing Index, can help doctors decide when it's safe to remove a breathing tube from patients in the intensive care unit. About 70 adults on ventilators will be monitored after tube removal to …

This study looks at whether measuring how much a vein near the armpit collapses with breathing can predict if a sepsis patient needs more fluids. It involves 40 spontaneously breathing adults with sepsis and signs of poor circulation. The goal is to find a simple, non-invasive wa…

This study looks at whether levels of a natural chemical called prostaglandin E2 can predict which premature babies will develop a serious heart condition called patent ductus arteriosus (PDA). Researchers will measure this chemical in 34 preterm infants born at 32 weeks or earli…

This study looks at three different scoring systems to see which best predicts the risk of death in patients with severe tetanus in the intensive care unit. Researchers will follow 115 adults diagnosed with tetanus for up to 90 days. The goal is to find a more accurate way to ide…

This study looks at whether using a blood test (anti-Xa) to adjust the dose of a blood thinner (enoxaparin) works better than dosing based on weight alone for preventing dangerous blood clots in burn patients. About 25 adults with serious burns will be enrolled. The goal is to se…