Ain Shams University

This study tests a less invasive way to treat receding gums using a collagen membrane instead of a tissue graft. Eighteen healthy adults with localized gum recession will receive one of two treatments. The goal is to see if the collagen membrane works as well as the standard graf…

This study compares three different medicines for treating infected baby molars in children aged 4 to 8. The goal is to see which works best to stop pain, swelling, and infection, and to test their ability to kill bacteria. The study involves 108 healthy children and aims to find…

This study tests whether a sedative called dexmedetomidine can lower the risk of acute kidney injury in adults undergoing ascending aortic surgery with a heart-lung machine. About 78 participants will receive either the drug or a placebo. The goal is to see if the drug's calming …

This study looked at whether giving N-acetyl cysteine (NAC) and vitamin D, along with standard care, can help children who swallowed a corrosive substance. The main goal was to see if these treatments could prevent narrowing of the food pipe (strictures) and speed up recovery. Ei…

This study looks at two different antibiotic treatments for burn patients who develop sepsis, a serious infection. Researchers want to see if one type (carbapenems) helps more patients survive compared to another type (noncarbapenem beta-lactams). The study involves 400 adults ag…

This study tests whether adding a small bone-drilling procedure (microfracture) to standard meniscus repair helps the knee heal better. Thirty adults aged 18-50 with isolated meniscus tears will be randomly assigned to get repair alone or repair plus microfracture. Researchers wi…

This study tests two different varnishes to see which works better at reversing white spot lesions—early signs of tooth decay—in people aged 15 to 25. Each participant gets one varnish on one side of their mouth and the other varnish on the opposite side. The goal is to measure c…

This study looks at whether giving extra sodium (salt) to premature babies starting at least one week after birth helps them gain weight and grow better. The trial includes 74 preterm infants with low birth weight. Researchers will track their weight for six weeks and check for s…

This study tests whether a daily dose of alpha lipoic acid, an antioxidant supplement, can reduce heart problems in children receiving hemodialysis. About 50 children will either take the supplement or a placebo pill. Researchers will track heart events like stroke and angina, an…

This study tests three special materials used to treat deep cavities in children's permanent molars that are still growing. The goal is to keep the tooth alive and allow the root to finish forming normally. Sixty-nine children aged 7 to 10 will receive one of the three materials …

This study compares two procedures to relieve chronic tailbone pain (coccydynia) that is not related to cancer. About 74 adults aged 20-70 who have not responded to standard medical treatment will be split into two groups. One group will receive conventional radiofrequency ablati…

This study tests whether adding dexamethasone or dexmedetomidine to a standard numbing medicine (bupivacaine) can provide longer pain relief after rhinoplasty (nose job). 90 adults having nose surgery will receive one of these combinations as a nerve block. The main goal is to se…

This study tests whether adding ketamine to dexmedetomidine sedation improves comfort and brain signal quality during awake deep brain stimulation surgery for movement disorders like Parkinson's disease. 24 adults will be randomly assigned to receive either the combination or dex…

This study looks at whether sugammadex, a drug used to reverse muscle relaxants, can lower the chance of agitation when adults wake up from nasal surgery. About 486 adults aged 18 to 60 having procedures like septoplasty or sinus surgery will be observed. The goal is to see if th…

This study compares two types of nerve blocks (RISS and QL) to see which provides better pain relief after open kidney removal. Fifty adults aged 40-70 having open nephrectomy will receive one of the two blocks. The main goal is to see how long it takes before they need additiona…

This study tests whether a special oxygen gel applied to stitches after oral surgery can improve wound healing and reduce bacteria. About 44 healthy adults who need dental surgery will receive either the oxygen gel or standard care. Researchers will check healing at 1 and 2 weeks…

This study tests whether a smartphone-based AI tool can help doctors give a pain-blocking injection to babies having cleft lip repair. The goal is to reduce pain during surgery and the need for extra pain medicine. The study includes 120 infants aged 5-18 months and compares the …

This study compares two types of nerve blocks (ESPB and QLB) for pain control after lower back surgery. Forty adults aged 18-65 will receive one of the two blocks, and researchers will measure pain levels using a simple 0-10 scale. The goal is to find which block provides better …

This study compares two dental treatments for a painful tooth condition called irreversible pulpitis. 34 adults will receive either vital pulp therapy or a standard root canal. The goal is to see which treatment causes less pain after the procedure and which leads to better heali…

This study compares two anesthesia methods—total intravenous anesthesia (TIVA) and balanced anesthesia (using inhaled gas)—in 60 diabetic adults undergoing video-assisted thoracoscopy (a minimally invasive chest surgery). The goal is to see which method better controls blood suga…

This study tests whether making small holes in the jawbone (micro-osteoperforations) helps clear aligners straighten crowded lower front teeth faster. Twenty adults with mild crowding will be treated with aligners, with half also getting the bone procedure. Researchers will compa…

This study looks at how common irregular periods are in teen girls with type 1 diabetes and tests whether a glucagon-like peptide-1 receptor agonist (a type of diabetes drug) can improve them. About 50 girls aged 12 to 18 with poor blood sugar control will take the drug for 3 mon…

This study looks at whether a numbing injection near the neck (superficial cervical plexus block) can reduce pain after ear surgery. About 46 adults aged 20-40 will either get the block plus general anesthesia or just general anesthesia. The goal is to see if the block lowers pai…

This study looks at whether using a second sperm sample from the same man can lead to better fertilization and embryo development during ICSI (a type of IVF). It involves 108 couples where the male partner has abnormal sperm. The goal is to see if the second sample has more healt…

This study looks at how kangaroo mother care (skin-to-skin contact) affects energy use in preterm babies born at 32-36 weeks. Researchers will measure urine markers of energy and stress, along with heart rate, breathing, and temperature. The goal is to understand if this simple, …

This study looks at how two different types of anesthesia affect inflammation after inguinal hernia repair. Forty adults having hernia surgery will be randomly assigned to receive either total intravenous anesthesia (TIVA) or inhaled anesthesia. Researchers will measure inflammat…

This study looks at 37 children with acute respiratory distress syndrome (ARDS) who are on breathing machines. Researchers want to see if measuring certain inflammation markers in saliva works as well as measuring them in fluid from the lungs. If saliva works, it could lead to a …

This study looks at how many screws are best for holding a full set of replacement teeth on dental implants. Researchers compared using 3 screws versus 4 screws in 14 men who have no natural teeth left. The goal is to see which method causes less bone loss around the implants ove…

This study looks at how head and neck position (sniffing vs. ramped) and the type of blade used on a video laryngoscope affect how quickly a breathing tube can be placed in 140 severely obese patients (BMI 40 or higher) undergoing elective surgery. The goal is to find the best co…

This study looks at whether changes in a blood protein called albumin can predict how sepsis patients in the ICU will do, compared to the usual test for lactic acid. Researchers will track 40 non-surgical ICU patients with sepsis to see which measurement better forecasts recovery…

This study compares two ways to predict if placing a breathing tube in a child will be difficult: an ultrasound of the airway versus a standard physical exam. Researchers will watch 130 children having planned surgery to see which method works better. The goal is to improve safet…

This study follows 100 head and neck cancer patients receiving standard radiotherapy to see how their teeth, gums, and saliva change over time. Researchers measure gum health, tooth condition, and quality of life before and after treatment. The goal is to better understand long-t…

This study looks at how two types of occlusal veneers (thin covers for back teeth) hold up under different biting forces. Researchers will use computer simulations and check the veneers in 8 adults aged 25-35 with certain cavities. The goal is to see which veneer type resists wea…

This study compares two modern ways to make dental onlays (tooth restorations): 3D-printing versus milling from a solid block. Thirty adults with cavities, broken teeth, or old fillings will receive either type of onlay. Researchers will check how well the onlays fit and perform …